Resistance of Helicobacter pylori to antibiotics from 2000 to 2009 in Shanghai.

AIM To investigate the resistance of Helicobacter pylori (H. pylori) to 6 commonly used antibiotics from 2000 to 2009 in Shanghai. METHODS A total of 293 H. pylori strains were collected from 2000 to 2009 in Shanghai and tested for their susceptibility to metronidazole, clarithromycin, amoxicillin, furazolidone, levofloxacin and tetracycline using agar dilution. RESULTS The resistant rates of H. pylori to clarithromycin (8.6%, 9.0% and 20.7%) and levofloxacin (10.3%, 24.0% and 32.5%) increased from 2000 to 2009 in Shanghai. The resistant rate of H. pylori to metronidazole remained stable (40%-50%). Only one strain of H. pylori isolated in 2005 was resistant to tetracycline. All strains were sensitive to amoxicillin and furazolidone. The resistant rate of H. pylori to antibiotics was not related with the sex, age and clinical outcome of patients. CONCLUSION Resistance of H. pylori to antibiotics plays an important role in making treatment strategies against H. pylori-associated diseases.

• Publication year

  2010

• Venue

  World Journal of Gastroenterology

• Publication date

  2010-10-28

• Fields of study

  Medicine

• Identifiers
  DOI 10.3748/WJG.V16.I40.5118PMID 20976850PMCID PMC2965290
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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