Serum leptin and adiponectin levels and risk of renal cell carcinoma

L. Liao,K. Schwartz,M. Pollak,B. Graubard,Zhen Li,J. Ruterbusch,N. Rothman,F. Davis,S. Wacholder,J. Colt,W. Chow,M. Purdue

Published 2012 in Obesity

ABSTRACT

The incidence of renal cell carcinoma (RCC) has increased rapidly in the U.S., particularly among African Americans. Despite a well‐established link between obesity and RCC, the mechanism through which obesity increases cancer risk has yet to be established. Adipokines, such as leptin and adiponectin, may link obesity and cancer, with different quantitative effects by race.

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