The association between inadequate sleep and accelerated brain ageing

Jivesh Ramduny,M. Bastiani,Robin Huedepohl,S. Sotiropoulos,M. Chechlacz

Published 2022 in Neurobiology of Aging

ABSTRACT

Highlights • Inadequate sleep accelerates brain ageing (deviation above the chronological age).• Brain age delta is a highly sensitive marker linking poor sleep to brain ageing.• Multimodal analyses of brain ageing outperform unimodal approaches.• Bias correction (removal of age-related bias) improves estimates of brain age delta.

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