ER-bound steps in the biosynthesis of G protein-coupled receptors.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Sub-cellular biochemistry

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/978-94-007-4765-4_1PMID 23161130
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Functional significance of cleavable signal peptides of G protein-coupled receptors.

  2012cited by this paper
• Diversity and modularity of G protein-coupled receptor structures.

  2012cited by this paper
• Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein

  2011cited by this paper
• The cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutants.

  2011cited by this paper
• Evolution of three human GPCRs for higher expression and stability.

  2011cited by this paper
• Robust post-translocational N-glycosylation at the extreme C-terminus of membrane and secreted proteins in Xenopus laevis oocytes and HEK293 cells.

  2011cited by this paper
• Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems.

  2011cited by this paper
• Two distinct conformations of helix 6 observed in antagonist-bound structures of a β1-adrenergic receptor

  2011cited by this paper
• Pharmacochaperoning of the A1 Adenosine Receptor Is Contingent on the Endoplasmic Reticulum

  2010cited by this paper
• A Comprehensive Comparison of Transmembrane Domains Reveals Organelle-Specific Properties

  2010cited by this paper
• The Pseudo Signal Peptide of the Corticotropin-releasing Factor Receptor Type 2a Decreases Receptor Expression and Prevents Gi-mediated Inhibition of Adenylyl Cyclase Activity*

  2010cited by this paper
• Regulation of G‐Protein Coupled Receptor Traffic by an Evolutionary Conserved Hydrophobic Signal

  2010cited by this paper
• Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP.

  2010cited by this paper
• Human β1-Adrenergic Receptor Is Subject to Constitutive and Regulated N-terminal Cleavage*

  2010cited by this paper
• Transmembrane helical domain of the cannabinoid CB1 receptor.

  2009cited by this paper
• Topology of Class A G Protein-Coupled Receptors: Insights Gained from Crystal Structures of Rhodopsins, Adrenergic and Adenosine Receptors

  2009cited by this paper
• Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase.

  2009cited by this paper
• The structure and function of G-protein-coupled receptors

  2009cited by this paper
• Intrinsic conformational determinants signal protein misfolding to the Hrd1/Htm1 endoplasmic reticulum-associated degradation system.

  2009cited by this paper
• Calnexin Improves the Folding Efficiency of Mutant Rhodopsin in the Presence of Pharmacological Chaperone 11-cis-Retinal*

  2009cited by this paper
• Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein

  2009cited by this paper
• Anterograde Trafficking of G Protein-Coupled Receptors: Function of the C-Terminal F(X)6LL Motif in Export from the Endoplasmic Reticulum

  2009cited by this paper
• The ER‐resident ubiquitin‐specific protease 19 participates in the UPR and rescues ERAD substrates

  2009cited by this paper
• The length of cargo-protein transmembrane segments drives secretory transport by facilitating cargo concentration in export domains

  2009cited by this paper
• The Mammalian Hsp40 ERdj3 Requires Its Hsp70 Interaction and Substrate-binding Properties to Complement Various Yeast Hsp40-dependent Functions*

  2009cited by this paper
• Transmembrane domain–dependent partitioning of membrane proteins within the endoplasmic reticulum

  2008cited by this paper
• Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum

  2008cited by this paper
• Peptide-based interactions with calnexin target misassembled membrane proteins into endoplasmic reticulum-derived multilamellar bodies.

  2008cited by this paper
• Specific transmembrane segments are selectively delayed at the ER translocon during opsin biogenesis.

  2008cited by this paper
• One step at a time: endoplasmic reticulum-associated degradation

  2008cited by this paper
• N-Glycosylation of the human kappa opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway.

  2007cited by this paper
• Opioid Receptor Pharmacological Chaperones Act by Binding and Stabilizing Newly Synthesized Receptors in the Endoplasmic Reticulum*

  2007cited by this paper
• In and out of the ER: protein folding, quality control, degradation, and related human diseases.

  2007cited by this paper
• The endoplasmic reticulum Ca2+-pump SERCA2b interacts with G protein-coupled receptors and enhances their expression at the cell surface.

  2007cited by this paper
• Role of group-conserved residues in the helical core of β2-adrenergic receptor

  2007cited by this paper
• Regulation of G protein-coupled receptor export trafficking.

  2007cited by this paper
• The Highly Conserved DRY Motif of Class A G Protein-Coupled Receptors: Beyond the Ground State

  2007cited by this paper
• The Ubiquitin-Specific Protease Usp4 Regulates the Cell Surface Level of the A2a Receptor

  2006cited by this paper
• The Corticotropin-releasing Factor Receptor Type 2a Contains an N-terminal Pseudo Signal Peptide*

  2006cited by this paper
• Protein folding as posttranslational regulation: evolution of a mechanism for controlled plasma membrane expression of a G protein-coupled receptor.

  2006cited by this paper
• Pharmacological Chaperone Activity of SR49059 to Functionally Recover Misfolded Mutations of the Vasopressin V1a Receptor*

  2006cited by this paper
• The diversity of the DnaJ/Hsp40 family, the crucial partners for Hsp70 chaperones

  2006cited by this paper
• Mechanisms of Cell-surface Rerouting of an Endoplasmic Reticulum-retained Mutant of the Vasopressin V1b/V3 Receptor by a Pharmacological Chaperone*

  2005cited by this paper
• The hydrophobic amino acid residues in the membrane‐proximal C tail of the G protein‐coupled vasopressin V2 receptor are necessary for transport‐competent receptor folding

  2005cited by this paper
• Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

  2004cited by this paper
• Intracellularly located misfolded glycoprotein hormone receptors associate with different chaperone proteins than their cognate wild-type receptors.

  2004cited by this paper
• Distinct Machinery Is Required in Saccharomyces cerevisiae for the Endoplasmic Reticulum-associated Degradation of a Multispanning Membrane Protein and a Soluble Luminal Protein*

  2004cited by this paper
• Truncation of the A1 Adenosine Receptor Reveals Distinct Roles of the Membrane-proximal Carboxyl Terminus in Receptor Folding and G Protein Coupling*

  2003cited by this paper
• Formation of stacked ER cisternae by low affinity protein interactions

  2003cited by this paper
• The Chaperone Environment at the Cytoplasmic Face of the Endoplasmic Reticulum Can Modulate Rhodopsin Processing and Inclusion Formation*

  2003cited by this paper
• A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist

  2002cited by this paper
• Purification and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli

  2002cited by this paper
• Purification and characterization of the human adenosine A(2a) receptor functionally expressed in Escherichia coli.

  2002cited by this paper
• Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein

  2001cited by this paper
• Identification of the glycosylation sites utilized on the V1a vasopressin receptor and assessment of their role in receptor signalling and expression.

  2001cited by this paper
• Serine and alanine mutagenesis of the nine native cysteine residues of the human A(1) adenosine receptor.

  2000cited by this paper
• Bacterial expression of G-protein-coupled receptors: prediction of expression levels from sequence.

  2000cited by this paper
• N-Linked Glycosylation Is Required for Optimal AT1a Angiotensin Receptor Expression in COS-7 Cells.

  1999cited by this paper
• Conserved Extracellular Cysteine Pair in the M3 Muscarinic Acetylcholine Receptor Is Essential for Proper Receptor Cell Surface Localization but Not for G Protein Coupling

  1999cited by this paper
• A Single Negatively Charged Residue Affects the Orientation of a Membrane Protein in the Inner Membrane of Escherichia coliOnly When It Is Located Adjacent to a Transmembrane Domain*

  1999cited by this paper
• Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation.

  1998cited by this paper
• Identification of Membrane Insertion Sequences of the Rabbit Gastric Cholecystokinin-A Receptor by in VitroTranslation*

  1997cited by this paper
• Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled.

  1997cited by this paper
• Plasma Membrane Localization and Functional Rescue of Truncated Forms of a G Protein-coupled Receptor (*)

  1995cited by this paper
• Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.

  1994cited by this paper
• The high affinity state of the beta 2-adrenergic receptor requires unique interaction between conserved and non-conserved extracellular loop cysteines.

  1994cited by this paper
• Functional role of proline and tryptophan residues highly conserved among G protein‐coupled receptors studied by mutational analysis of the m3 muscarinic receptor.

  1993cited by this paper
• Functional expression of the human serotonin 5-HT1A receptor in Escherichia coli. Ligand binding properties and interaction with recombinant G protein alpha-subunits.

  1992cited by this paper
• Expression of two human beta-adrenergic receptors in Escherichia coli: functional interaction with two forms of the stimulatory G protein.

  1991cited by this paper
• Multiple topogenic sequences in bovine opsin.

  1987cited by this paper

• Functional Impact of the G279S Substitution in the Adenosine A1-Receptor (A1R-G279S7.44), a Mutation Associated with Parkinson’s Disease

  2020cites this paper
• Functional impact of the G279S substitution in the adenosine A1-receptor (A1R-G279S), a mutation associated with Parkinson's disease.

  2020cites this paper
• Advances in Membrane Proteins: Building, Signaling and Malfunction

  2019cites this paper
• The Biosynthesis and Folding of Oily Peptide Chains

  2019cites this paper
• A unique signal sequence of the chemokine receptor CCR7 promotes package into COPII vesicles for efficient receptor trafficking

  2018cites this paper
• Hyponatremia and V2 vasopressin receptor upregulation: a result of HSP90 inhibition

  2017cites this paper
• Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters

  2017cites this paper
• Comparison of the β-Adrenergic Receptor Antagonists Landiolol and Esmolol: Receptor Selectivity, Partial Agonism, and Pharmacochaperoning Actions

  2016cites this paper
• Chaperoning of the A1-Adenosine Receptor by Endogenous Adenosine—An Extension of the Retaliatory Metabolite Concept

  2015cites this paper
• Pharmacological characterization and functional rescue of human melanocortin-4 receptor mutants

  2014cites this paper
• Chaperoning G protein-coupled receptors: from cell biology to therapeutics.

  2014cites this paper
• Chaperoning of the A 1-Adenosine Receptor by Endogenous Adenosine — An Extension of the Retaliatory Metabolite Concept s

  2014cites this paper
• Selection on synonymous codons in mammalian rhodopsins: a possible role in optimizing translational processes

  2014cites this paper
• Recruitment of a Cytoplasmic Chaperone Relay by the A2A Adenosine Receptor

  2013cites this paper