Human parathyroid hormone (PTH)-related protein and human PTH: comparative biological activities on human bone cells and bone resorption.

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Endocrinology

• Publication date

  1988-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/ENDO-123-6-2841PMID 2848688
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Humoral hypercalcemia of malignancy.

  1990cited by this paper
• Humoral hypercalcemia of malignancy.

  1989cited by this paper
• The parathyroid hormone-like peptide associated with humoral hypercalcemia of malignancy and parathyroid hormone bind to the same receptor on the plasma membrane of ROS 17/2.8 cells.

  1988cited by this paper
• Comparison of postreceptor effects of 1-34 human hypercalcemia factor and 1-34 human parathyroid hormone in rat osteosarcoma cells.

  1988cited by this paper
• Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy.

  1988cited by this paper
• Synthetic human parathyroid hormone-like protein stimulates bone resorption and causes hypercalcemia in rats.

  1988cited by this paper
• Effects of a synthetic peptide of a parathyroid hormone-related protein on calcium homeostasis, renal tubular calcium reabsorption, and bone metabolism in vivo and in vitro in rodents.

  1988cited by this paper
• Synthetic and partially-purified adenylate cyclase-stimulating proteins from tumors associated with humoral hypercalcemia of malignancy inhibit phosphate transport in a PTH-responsive renal cell line.

  1988cited by this paper
• Similarity of synthetic peptide from human tumor to parathyroid hormone in vivo and in vitro.

  1987cited by this paper
• A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression.

  1987cited by this paper
• Characterization of a human osteosarcoma cell line (Saos-2) with osteoblastic properties.

  1987cited by this paper
• Tumor necrosis factor-alpha (cachectin) stimulates bone resorption in mouse calvaria via a prostaglandin-mediated mechanism.

  1987cited by this paper
• Palytoxin: an extraordinarily potent stimulator of prostaglandin production and bone resorption in cultured mouse calvariae.

  1987cited by this paper
• Parathyroid hormone-related protein of malignancy: active synthetic fragments.

  1987cited by this paper
• Parathyroid hormone-related protein purified from a human lung cancer cell line.

  1987cited by this paper
• Parathyroid hormonelike protein from human renal carcinoma cells. Structural and functional homology with parathyroid hormone.

  1987cited by this paper
• A parathyroid hormone-like protein from cultured human keratinocytes.

  1986cited by this paper
• Nephrogenous cyclic AMP, adenylate cyclase-stimulating activity, and the humoral hypercalcemia of malignancy.

  1986cited by this paper
• Measurement of cytosolic free Ca2+ concentrations in human and rat osteosarcoma cells: actions of bone resorption-stimulating hormones.

  1986cited by this paper
• Alpha and beta human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria.

  1985cited by this paper
• Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model

  1985cited by this paper
• Functional receptors for vasoactive intestinal peptide on human osteosarcoma cells.

  1984cited by this paper
• Bone resorption in organ culture: inhibition by the divalent cation ionophores A23187 and X-537A.

  1976cited by this paper
• A simple ultrasensitive method for the assay of cyclic AMP and cyclic GMP in tissues.

  1976cited by this paper
• Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis.

  1975cited by this paper

• Lung tumor cells inhibit bone mineralization and osteoblast activity.

  2019cites this paper
• Parathyroid Hormone-Related Protein Negatively Regulates Tumor Cell Dormancy Genes in a PTHR1/Cyclic AMP-Independent Manner

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• Different expression and localization of Phosphoinositide specific Phospholipases C in human osteoblasts, osteosarcoma cell lines, Ewing Sarcoma and Synovial Sarcoma.

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• Pathology of Bone and Joint Disorders: Anatomy and physiology of bone

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• Cyclic AMP formation in rat bone and kidney cells is stimulated equally by parathyroid hormone-related protein (PTHrP) 1-34 and PTH 1-34.

  2009cites this paper
• Stimulation by Parathyroid Hormone-Related Protein and Transforming Growth Factor-a

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• Osteoclast culture and resorption assays.

  2008cites this paper
• Chapter 32 – Calcium-Regulating Hormones

  2004cites this paper
• Expression and Function(s) of Parathyroid Hormone- Related Peptide in Intramembranous Bone Formation by Neonatal Rat Calvarial Cells In Vitro

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• Novel and Selective Small Molecule Stimulators of Osteoprotegerin Expression Inhibit Bone Resorption

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• Apoptotic and proliferative activity in Neuroblastoma and PNET, tumors of the Thyroid gland and Parathyroid gland

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• Phospholipase C axis is the preferential pathway leading to PKC activation following PTH or PTHrP stimulation in human term placenta.

  2002cites this paper
• Discovery of a non-peptide small molecule that selectively mimics the biological actions of calcitonin.

  2001cites this paper
• Trichorzin HA V, a member of the peptaibol family, stimulates intracellular cAMP formation in cells expressing the calcitonin receptor.

  2001cites this paper
• Direct Measurement of Hormone‐Induced Acidification in Intact Bone

  2000cites this paper
• A Chimeric Form of Osteoprotegerin Inhibits Hypercalcemia and Bone Resorption Induced by IL‐1β, TNF‐α, PTH, PTHrP, and 1,25(OH)2D3

  1999cites this paper
• Studies of Interactions Between Myeloma Cells and Osteoblasts In Vitro

  1999cites this paper
• A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.

  1999cites this paper
• Pathology of Bone and Joint Disorders with Clinical and Radiographic Correlation

  1998cites this paper
• A New Action of Parathyroid Hormone

  1997cites this paper
• Parathyroid hormone (1‐34)–mediated interleukin‐6 induction

  1997cites this paper
• Pituitary adenylate cyclase-activating peptide stimulates cyclic AMP accumulation in UMR 106 osteoblast-like cells.

  1996cites this paper
• Hyperparathyroidism.

  1996cites this paper
• Cultured human fibroblasts and not cultured human keratinocytes express a PTH/PTHrP receptor mRNA.

  1995cites this paper
• Comparison of the pharmacokinetics of parenteral parathyroid hormone-(1-34) [PTH-(1-34)] and PTH-related peptide-(1-34) in healthy young humans.

  1995cites this paper
• [Parathyroid hormone related peptide (PTHrP) and bone metabolism].

  1995cites this paper
• Inhibition of parathyroid hormone-related protein release by extracellular calcium in dispersed cells from human parathyroid hyperplasia secondary to chronic renal failure and adenoma.

  1995influential citation
• Peptide Apparenté à l'hormone Parathyroidienne (Pthrp) Et Métabolisme Osseux

  1995cites this paper
• Matrix deposition by a calcifying human osteogenic sarcoma cell line (SAOS-2).

  1995cites this paper
• PTH and PTH-rP elicit dissimilar retractile responses in murine MC3T3-E1 osteoblasts.

  1994cites this paper
• Rapid desensitization of parathyroid hormone dependent adenylate cyclase in perifused human osteosarcoma cells (SaOS-2).

  1994cites this paper
• Preclinical pharmacology of CGP 42′446, a new, potent, heterocyclic bisphosphonate compound

  1994cites this paper
• Antisense-mediated inhibition of parathyroid hormone-related peptide production in a keratinocyte cell line impedes differentiation.

  1994cites this paper
• Involvement of alkaline phosphatase in the modulation of receptor signaling in osteoblasts: Evidence for a difference between human parathyroid hormone‐related protein and human parathyroid hormone

  1994cites this paper
• Preserved bone mass in ovariectomized rats treated with parathyroid-hormone-related peptide (1-34) and (107-111) fragments.

  1994cites this paper
• Parathyroid hormone-like peptide and parathyroid hormone are secreted from bovine parathyroid via different pathways.

  1993cites this paper
• Biosynthesis and processing of endogenous parathyroid hormone related peptide (PTHRP) by rat Leydig cell tumor H-500.

  1993cites this paper
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  1993cites this paper
• Effect of parathyroid-hormone-related protein on sodium-dependent phosphate transport in renal brush border membrane vesicles in rats. Comparison with parathyroid hormone.

  1993cites this paper
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  1992cites this paper
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  1992cites this paper
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  1992cites this paper
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  1992cites this paper
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  1992cites this paper
• [Parathyroid-related protein (PTH-rP): from humoral hypercalcemia to physiological hormone].

  1992cites this paper
• Enhanced growth of a human keratinocyte cell line induced by antisense RNA for parathyroid hormone-related peptide.

  1992cites this paper
• A parathyroid-related peptide induces transcaltachia (the rapid, hormonal stimulation of intestinal Ca2+ transport).

  1992cites this paper
• Biologic activities of parathyroid hormone (1-34) and parathyroid hormone-related peptide (1-34) in isolated perfused rat femur.

  1992cites this paper
• A comparison of the in vivo biochemical responses to exogenous parathyroid hormone-(1-34) [PTH-(1-34)] and PTH-related peptide-(1-34) in man.

  1992cites this paper
• The effect of retinoic acid on parathyroid hormone- and parathyroid hormone-related peptide-induced intracellular calcium in a rat osteosarcoma cell line, UMR106.

  1991cites this paper
• The activation of cAMP-dependent protein kinase is directly linked to the inhibition of osteoblast proliferation (UMR-106) by parathyroid hormone-related protein.

  1991cites this paper
• Stimulation by parathyroid hormone‐related protein and transforming growth factor‐α of phosphate transport in osteoblast‐like cells

  1991cites this paper
• Methodology for the Study of Metabolism: Cellular and Molecular Techniques

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• Effects of transforming growth factor-α on parathyroid hormone- and parathyroid hormone-related protein- mediated bone resorption and adenylate cyclase stimulation in vitro☆

  1991cites this paper
• Adenylate cyclase stimulating activity immunologically similar to parathyroid hormone‐related peptide can be extracted from fetal rat long bones

  1991influential citation
• Expression of the parathyroid hormone-related peptide gene in rat tissues.

  1991cites this paper
• Effects of transforming growth factor-alpha on parathyroid hormone- and parathyroid hormone-related protein-mediated bone resorption and adenylate cyclase stimulation in vitro.

  1991cites this paper
• Structural requirements for the action of parathyroid hormone‐related protein (PTHrP) on bone resorption by isolated osteoclasts

  1991cites this paper
• Physiological and pharmacological regulation of biological calcification.

  1991cites this paper
• Inhibition of renal membrane adenylate cyclase by extract of pancreatic cancer associated with humoral hypercalcemia of malignancy.

  1990cites this paper
• Differential effects of continuous and transient treatment with parathyroid hormone related peptide (PTHrp) on bone collagen synthesis.

  1990cites this paper
• Stimulation by parathyroid hormone of 45Ca2+ uptake in osteoblast-like cells: possible involvement of alkaline phosphatase.

  1990cites this paper
• Desensitization of parathyroid hormone receptors on cultured bone cells

  1990cites this paper
• Modifications of position 12 in parathyroid hormone and parathyroid hormone related protein: toward the design of highly potent antagonists.

  1990cites this paper
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  1990cites this paper
• [The role of a parathyroid hormone analogue in the pathogenesis of malignant hypercalcemia].

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• Parathyroid hormone-receptor interactions.

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• Role of Parathyroid Hormone in Bone Formation and Resorption

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• Separation of Parathyroid Hormome-Like Activity from Transforming Growth Factor-α and -β in the Canine Adenocarcinoma (CAC-8) Model of Humoral Hypercalcemia of Malignancy

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• Separation of parathyroid hormone-like activity from transforming growth factor-alpha and -beta in the canine adenocarcinoma (CAC-8) model of humoral hypercalcemia of malignancy.

  1989cites this paper
• Parathyroid hormone-related peptide transiently increases cytosolic calcium in osteoblast-like cells: comparison with parathyroid hormone.

  1989cites this paper
• Two squamous cell carcinomas not associated with humoral hypercalcemia produce a potent bone resorption-stimulating factor which is interleukin-1 alpha.

  1989cites this paper
• Parathyroid hormone-like proteins: biochemical responses and receptor interactions.

  1989cites this paper
• Parathyroid hormone-like peptide: molecular characterization and biological properties.

  1989cites this paper
• [PTH-like tumor peptide and malignant hypercalcemia].

  1989cites this paper
• Parathyroid hormone‐related protein relaxes rat gastric smooth muscle and shows cross‐desensitization with parathyroid hormone

  1989cites this paper
• Direct modulation by estradiol of the response of human bone cells (SaOS-2) to human parathyroid hormone (PTH) and PTH-related protein.

  1989cites this paper
• Renal vasodilatation and microvessel adenylate cyclase stimulation by synthetic parathyroid hormone-like protein fragments.

  1989cites this paper