The differential role of the lipid raft-associated protein flotillin 2 for progression of myeloid leukemia

Key Points The lipid raft protein flotillin 2 differentially influences disease course in murine CML, but not AML. The flotillin 2-CD44-CDC42 axis regulates CML via an impact on the cytoskeleton and homing ability of leukemia- initiating cells.

• Publication year

  2022

• Venue

  Blood Advances

• Publication date

  2022-03-17

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/bloodadvances.2021005992PMID 35298613PMCID 9631564
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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