Natural genetic engineering: A programmed chromosome/DNA elimination.

M. Kloc,J. Kubiak,R. Ghobrial

Published 2022 in Developmental Biology

ABSTRACT

Typically, all cells of a given organism have the same set of chromosomes. However, there are exceptions to this rule, and in many organisms, the somatic cells and germ cells, various types of somatic cells or organs, or females and males, have different genomes. One of the sources of such differences is chromosome/DNA elimination/chromatin diminution that is a naturally programmed phenomenon. We describe chromosome/DNA elimination in various organisms and present the current hypotheses on its origin, mechanisms, significance, and consequences.

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