Differential effects of peripheral and brain tumor necrosis factor on inflammation, sickness, emotional behavior and memory in mice.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Brain, behavior, and immunity

• Publication date

  2016-11-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1016/j.bbi.2016.08.001PMID 27515532
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Depression in Autoimmune Diseases.

  2016cited by this paper
• Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase.

  2016cited by this paper
• Mouse psychosocial stress reduces motivation and cognitive function in operant reward tests: A model for reward pathology with effects of agomelatine.

  2016cited by this paper
• Intra-amygdala microinjection of TNF-α impairs the auditory fear conditioning of rats via glutamate toxicity.

  2015cited by this paper
• Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABAB receptors associated with mood disorders

  2015cited by this paper
• Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling.

  2015cited by this paper
• CD40-TNF activation in mice induces extended sickness behavior syndrome co-incident with but not dependent on activation of the kynurenine pathway.

  2015cited by this paper
• Hippocampal synaptic plasticity, spatial memory and anxiety

  2014influential reference
• Amygdala microcircuits controlling learned fear.

  2014cited by this paper
• Mouse social stress induces increased fear conditioning, helplessness and fatigue to physical challenge together with markers of altered immune and dopamine function.

  2014cited by this paper
• Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain

  2013influential reference
• A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers.

  2013cited by this paper
• Altered cognitive-emotional behavior in early experimental autoimmune encephalitis--cytokine and hormonal correlates.

  2013cited by this paper
• Systemic Immune Activation Leads to Neuroinflammation and Sickness Behavior in Mice

  2013cited by this paper
• Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice

  2013cited by this paper
• Systemic tumor necrosis factor-alpha decreases brain stimulation reward and increases metabolites of serotonin and dopamine in the nucleus accumbens of mice.

  2013influential reference
• Dorsal periaqueductal gray-amygdala pathway conveys both innate and learned fear responses in rats

  2013cited by this paper
• Toward the future of psychiatric diagnosis: the seven pillars of RDoC

  2013influential reference
• Stress-Induced Recruitment of Bone Marrow-Derived Monocytes to the Brain Promotes Anxiety-Like Behavior

  2013cited by this paper
• The contextual brain: implications for fear conditioning, extinction and psychopathology

  2013influential reference
• CD40 activation induces NREM sleep and modulates genes associated with sleep homeostasis.

  2013cited by this paper
• TNF-α-mediated anxiety in a mouse model of multiple sclerosis.

  2012cited by this paper
• Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge.

  2012influential reference
• Depressive-like behavior induced by tumor necrosis factor-α in mice.

  2012influential reference
• Neural and cellular mechanisms of fear and extinction memory formation.

  2012influential reference
• Establishing a learned-helplessness effect paradigm in C57BL/6 mice: behavioural evidence for emotional, motivational and cognitive effects of aversive uncontrollability per se.

  2012cited by this paper
• Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens.

  2012influential reference
• The neurobiology of anhedonia and other reward-related deficits.

  2012cited by this paper
• In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma.

  2011cited by this paper
• Molecular mechanisms of fear learning and memory.

  2011cited by this paper
• Levels and Determinants of Inflammatory Biomarkers in a Swiss Population-Based Sample (CoLaus Study)

  2011cited by this paper
• Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: multiplex quantification with path analysis.

  2011cited by this paper
• A meta-analysis of cytokines in major depression.

  2010cited by this paper
• Regionally-specific changes in levels of tumour necrosis factor in the dorsolateral prefrontal cortex obtained postmortem from subjects with major depressive disorder.

  2010cited by this paper
• Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression.

  2009cited by this paper
• Genome-wide association studies for complex traits: consensus, uncertainty and challenges

  2008cited by this paper
• Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro.

  2008cited by this paper
• The type 1 TNF receptor and its associated adapter protein, FAN, are required for TNFα-induced sickness behavior

  2008cited by this paper
• The inflammatory response to social defeat is increased in older mice.

  2008cited by this paper
• From inflammation to sickness and depression: when the immune system subjugates the brain

  2008influential reference
• Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

  2007cited by this paper
• The STAR*D project results: A comprehensive review of findings

  2007cited by this paper
• Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive-like behavior.

  2007cited by this paper
• TNFα-induced sickness behavior in mice with functional 55 kD TNF receptors is blocked by central IGF-I

  2007cited by this paper
• TNF-alpha suppresses the expression of clock genes by interfering with E-box-mediated transcription.

  2007cited by this paper
• Consensus paper of the WFSBP Task Force on Biological Markers: Biological Markers in Depression

  2007cited by this paper
• Endogenous glucocorticoids protect against TNF-alpha-induced increases in anxiety-like behavior in virally infected mice

  2007cited by this paper
• TNF-α suppresses the expression of clock genes by interfering with E-box-mediated transcription

  2007cited by this paper
• Named Series: Twenty Years of Brain, Behavior, and Immunity Twenty years of research on cytokine-induced sickness behavior

  2007influential reference
• Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial.

  2006cited by this paper
• The Dark Side of EGFP: Defective Polyubiquitination

  2006influential reference
• Contributions of the amygdala to emotion processing: from animal models to human behavior.

  2005cited by this paper
• The taste of sickness: lipopolysaccharide-induced finickiness in rats.

  2005influential reference
• Systemic administration of lipopolysaccharide and interleukin-1beta have different effects on memory consolidation.

  2005cited by this paper
• Transduction Profiles of Recombinant Adeno-Associated Virus Vectors Derived from Serotypes 2 and 5 in the Nigrostriatal System of Rats

  2004cited by this paper
• Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain

  2003influential reference
• Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo

  2003influential reference
• Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain.

  2003cited by this paper
• Constitutive expression of p55TNFR mRNA and mitogen‐specific up‐regulation of TNFα and p75TNFR mRNA in mouse brain

  2003cited by this paper
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

  2002cited by this paper
• Identification of Tumor Necrosis Factor (TNF) Amino Acids Crucial for Binding to the Murine p75 TNF Receptor and Construction of Receptor-selective Mutants*

  2001cited by this paper
• Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

  2001cited by this paper
• Role of IL-6 in cytokine-induced sickness behavior: a study with IL-6 deficient mice.

  2000cited by this paper
• Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain

  2000cited by this paper
• Anxiolytic action on the behavioural inhibition system implies multiple types of arousal contribute to anxiety.

  2000cited by this paper
• Blood-brain barrier permeability in the periventricular areas of the normal mouse brain

  2000cited by this paper
• Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

  1999cited by this paper
• Effects of circulating tumor necrosis factor on the neuronal activity and expression of the genes encoding the tumor necrosis factor receptors (p55 and p75) in the rat brain: a view from the blood-brain barrier.

  1999influential reference
• Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide.

  1999influential reference
• Selective effects of peripheral lipopolysaccharide administration on contextual and auditory-cue fear conditioning.

  1998cited by this paper
• Trends in the safety of high dose bolus interleukin‐2 administration in patients with metastatic cancer

  1998cited by this paper
• Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation

  1997cited by this paper
• Evidence-Based Health Policy--Lessons from the Global Burden of Disease Study

  1996cited by this paper
• Permeability of the blood-brain barrier to soluble cytokine receptors.

  1995cited by this paper
• Evidence for an immune response in major depression: a review and hypothesis.

  1995cited by this paper
• Synergy between tumor necrosis factor alpha and interleukin-1 in the induction of sickness behavior in mice.

  1994influential reference
• Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear.

  1993cited by this paper
• The macrophage theory of depression.

  1991cited by this paper
• Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

  1987cited by this paper
• In vivo anti‐tumour activity of recombinant human and murine TNF, alone and in combination with murine IFN‐γ, on a syngeneic murine melanoma

  1986influential reference
• Characteristics of a human cell line transformed by DNA from human adenovirus type 5.

  1977cited by this paper
• On the permeability of the blood-brain barrier.

  1948influential reference

• The effect of milk fat globule membrane phospholipid supplementation on cognitive function in older adults with subjective memory complaints—a randomized, double-blind, placebo-controlled trial

  2025cites this paper
• Oral andrographolide loaded lipid nanocarriers alleviate stress behaviors and hippocampal damage in TNF alpha induced neuroinflammatory mice

  2025cites this paper
• A systematic approach to identify gaps in neuroimmunology: TNF-α and fear learning deficits, a worked example.

  2024influential citation
• Chronic Astrocytic TNFα Production in the Preoptic-Basal Forebrain Causes Aging-like Sleep–Wake Disturbances in Young Mice

  2024influential citation
• Obesity and Depression: Common Link and Possible Targets.

  2024cites this paper
• Inflammation in the pathogenesis of depression: a disorder of neuroimmune origin

  2023cites this paper
• Network pharmacology study on the mechanism of Qiangzhifang in the treatment of panic disorder

  2021cites this paper
• CD40 Agonist Monoclonal Antibody-Mediated Hepatitis in TNF-Receptor 1 Gene Knockout Mice

  2021cites this paper
• Tumor necrosis factor α negatively regulates the retrieval and reconsolidation of hippocampus-dependent memory.

  2021cites this paper
• Electroacupuncture Attenuates Neuropathic Pain and Comorbid Negative Behavior: The Involvement of the Dopamine System in the Amygdala

  2021cites this paper
• Somatostatin Receptor 4 Agonism Normalizes Stress-Related Excessive Amygdala Glutamate Release and Pavlovian Aversion Learning and Memory in Rodents

  2021cites this paper
• Long-term obesity is associated with depression and neuroinflammation

  2021cites this paper
• Inflammatory Bases of Neuropsychiatric Symptom Domains: Mechanisms and Specificity

  2021cites this paper
• New role of sertraline against Toxoplasma gondii‐induced depression‐like behaviours in mice

  2021cites this paper
• The Perfect Cytokine Storm: How Peripheral Immune Challenges Impact Brain Plasticity & Memory Function in Aging

  2021cites this paper
• Potentially obesogenic diets alter metabolic and neurobehavioural parameters in Wistar rats: a comparison between two dietary models.

  2020cites this paper
• Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor

  2020cites this paper
• Sex difference in the interrelationship between TNF-α and oxidative stress status in first-episode drug-naïve schizophrenia

  2020cites this paper
• Monocyte Mobilisation, Microbiota & Mental Illness.

  2019cites this paper
• Brain tumor necrosis factor-α mediates anxiety-like behavior in a mouse model of severe obesity.

  2019cites this paper
• Rapeseed oil fortified with micronutrients improves cognitive alterations associated with metabolic syndrome.

  2019cites this paper
• Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice

  2019cites this paper
• Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms

  2018cites this paper
• Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice

  2018cites this paper
• Peripheral Etanercept Administration Normalizes Behavior, Hippocampal Neurogenesis, and Hippocampal Reelin and GABAA Receptor Expression in a Preclinical Model of Depression

  2018cites this paper
• The Action Of Maternal Separation On Glutamate Receptors And Neuroinflammation: Role In Anxiety And Cocaine-reinforced Behavior.

  2018cites this paper
• Sex Differences in Context-Driven Reinstatement of Methamphetamine Seeking is Associated with Distinct Neuroadaptations in the Dentate Gyrus

  2018cites this paper
• Hippocampal neural progenitor cells play a distinct role in fear memory retrieval in male and female CIE rats

  2018cites this paper
• TNF&agr;‐dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen‐induced arthritis

  2018cites this paper
• Stereological Analysis of Microglia in Aged Male and Female Fischer 344 Rats in Socially Relevant Brain Regions.

  2018cites this paper
• Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm.

  2017cites this paper
• Obesity-Induced Neuroinflammation: Beyond the Hypothalamus.

  2017cites this paper
• Depression in the Context of Medical Disorders: New Pharmacological Pathways Revisited

  2017cites this paper
• IL-10 plays an important role in the control of inflammation but not in the bacterial burden in S. epidermidis CNS catheter infection

  2016cites this paper