RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-kappaB Activation Chronic NF-kappaB Activation Let us know how access to this document benefits you.

No abstract is available for this paper.

• Publication year

  2021

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Sequence Analysis

  2020cited by this paper
• Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death

  2018influential reference
• ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

  2018cited by this paper
• Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice.

  2018cited by this paper
• Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

  2017cited by this paper
• RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome

  2017cited by this paper
• Genetics and Pathogenesis of Inflammatory Bowel Disease.

  2016cited by this paper
• Cancer surveillance in ulcerative colitis and Crohn's disease: new strategies

  2016influential reference
• Characterization of GSK′963: a structurally distinct, potent and selective inhibitor of RIP1 kinase

  2015cited by this paper
• Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

  2015cited by this paper
• Necroptosis and its role in inflammation

  2015cited by this paper
• Oxidative Stress and DNA Damage: Implications in Inflammatory Bowel Disease

  2015cited by this paper
• Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease

  2015cited by this paper
• Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo

  2014cited by this paper
• The two faces of receptor interacting protein kinase-1.

  2014cited by this paper
• Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy

  2014influential reference
• Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis

  2014cited by this paper
• Regulated necrosis: the expanding network of non-apoptotic cell death pathways

  2014cited by this paper
• RIP3 induces apoptosis independent of pronecrotic kinase activity.

  2014cited by this paper
• Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death

  2013cited by this paper
• Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme.

  2013cited by this paper
• Critical contribution of oxidative stress to TNFα-induced necroptosis downstream of RIPK1 activation.

  2013cited by this paper
• Mucosal healing in inflammatory bowel diseases: a systematic review

  2012cited by this paper
• Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium

  2012cited by this paper
• Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation

  2012cited by this paper
• Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

  2012cited by this paper
• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

  2011cited by this paper
• Inflammatory bowel disease.

  2011cited by this paper
• Integrating diverse genomic data using gene sets

  2011cited by this paper
• RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

  2011cited by this paper
• Controlled gene expression in primary Lgr5 organoid cultures

  2011cited by this paper
• CASPASE 8 inhibits programmed necrosis by processing CYLD

  2011cited by this paper
• The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

  2011cited by this paper
• NOD2-mediated autophagy and Crohn disease

  2010cited by this paper
• Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

  2010cited by this paper
• The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

  2010cited by this paper
• RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

  2009cited by this paper
• The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology.

  2009cited by this paper
• Single Lgr5 stem cells build crypt–villus structures in vitro without a mesenchymal niche

  2009cited by this paper
• Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategies.

  2008influential reference
• Identification of RIP1 kinase as a specific cellular target of necrostatins.

  2008cited by this paper
• A Novel Inhibitory Mechanism of Mitochondrion-Dependent Apoptosis by a Herpesviral Protein

  2007cited by this paper
• TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death.

  2007cited by this paper
• Epithelial NEMO links innate immunity to chronic intestinal inflammation

  2007cited by this paper
• Transcriptional activation of survivin through the NF‐κB pathway by human T‐cell leukemia virus type I tax

  2005cited by this paper
• Kinase RIP3 Is Dispensable for Normal NF-κBs, Signaling by the B-Cell and T-Cell Receptors, Tumor Necrosis Factor Receptor 1, and Toll-Like Receptors 2 and 4

  2004cited by this paper
• IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium.

  2004cited by this paper
• Faculty Opinions recommendation of De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.

  2004cited by this paper
• Jaundice and anaemia

  2004cited by this paper
• TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains.

  2004cited by this paper
• NF-kappaB in cancer: a marked target.

  2003cited by this paper
• The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

  2003cited by this paper
• The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex*

  2002cited by this paper
• NF-κB Inducers Upregulate cFLIP, a Cycloheximide-Sensitive Inhibitor of Death Receptor Signaling

  2001cited by this paper
• Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation.

  1999cited by this paper
• Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.

  1998cited by this paper
• Tuberous sclerosis in two sibs of normal parents

  1991cited by this paper
• Constitutive intestinal NF-  B does not trigger destructive inflammation unless accompanied by MAPK activation

  year unknowninfluential reference

• No citing papers are available for this paper.