Peroxiredoxin 4: critical roles in inflammatory diseases.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of UOEH

• Publication date

  2012-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.7888/JUOEH.34.27PMID 22428456
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inflammation in Atherosclerosis

  2012cited by this paper
• Histamine Deficiency Decreases Atherosclerosis and Inflammatory Response in Apolipoprotein E Knockout Mice Independently of Serum Cholesterol Level

  2011cited by this paper
• Overexpression of Peroxiredoxin 4 Protects Against High-Dose Streptozotocin-Induced Diabetes by Suppressing Oxidative Stress and Cytokines in Transgenic Mice

  2010cited by this paper
• Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress.

  2009cited by this paper
• Immunolocalization of 8-OHdG and OGG1 in pancreatic islets of streptozotocin-induced diabetic rats.

  2009cited by this paper
• Analysis of 8-OH-dG and 8-OH-Gua as Biomarkers of Oxidative Stress

  2008cited by this paper
• β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

  2008cited by this paper
• Matrix metalloproteinase 12 accelerates the initiation of atherosclerosis and stimulates the progression of fatty streaks to fibrous plaques in transgenic rabbits.

  2008cited by this paper
• Role of crosstalk between phosphatidylinositol 3-kinase and extracellular signal-regulated kinase/mitogen-activated protein kinase pathways in artery-vein specification.

  2008cited by this paper
• Peroxiredoxin‐4 interacts with and regulates the thromboxane A2 receptor

  2007cited by this paper
• Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling.

  2005cited by this paper
• 2-Cys peroxiredoxin function in intracellular signal transduction: therapeutic implications

  2005cited by this paper
• Role of Histamine Produced by Bone Marrow–Derived Vascular Cells in Pathogenesis of Atherosclerosis

  2005cited by this paper
• Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells?

  2004cited by this paper
• The Cytokine Interleukin-1β Reduces the Docking and Fusion of Insulin Granules in Pancreatic β-Cells, Preferentially Decreasing the First Phase of Exocytosis*

  2004cited by this paper
• Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines.

  2004cited by this paper
• Peroxiredoxin 6 deficiency and atherosclerosis susceptibility in mice: significance of genetic background for assessing atherosclerosis.

  2004cited by this paper
• Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

  2003cited by this paper
• Inflammatory mediators and islet β-cell failure: a link between type 1 and type 2 diabetes

  2003cited by this paper
• b-Cell death during progression to diabetes

  2001cited by this paper
• The oxidant stress hypothesis of atherogenesis

  2001cited by this paper
• TNFα and IFNγ potentiate IL-1β induced mitogen activated protein kinase activity in rat pancreatic islets of Langerhans

  2000cited by this paper
• Atherosclerosis is an inflammatory disease

  1999cited by this paper
• Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

  1999cited by this paper
• Cloning of the peroxiredoxin gene family in rats and characterization of the fourth member

  1999cited by this paper
• Regulatory Role for a Novel Human Thioredoxin Peroxidase in NF-κB Activation*

  1997cited by this paper
• The oxidation hypothesis of atherosclerosis.

  1994cited by this paper

• PRDX-4: a novel biomarker similar to KL-6 for predicting the occurrence and progression of systemic sclerosis-ILD.

  2025cites this paper
• Histone lactylation protects against sevoflurane-induced cognitive impairment by regulating YTHDF3/PRDX3 mediated microglial pyroptosis in neonatal mice.

  2025cites this paper
• Prdx5 regulates macrophage polarization by modulating the TLR4/NF-κB pathway to promote apoptosis in chronic prostatitis.

  2025cites this paper
• A comprehensive review of peroxiredoxin 4, a redox protein evolved in oxidative protein folding coupled with hydrogen peroxide detoxification.

  2024cites this paper
• Evidence of traditional Chinese medicine for treating type 2 diabetes mellitus: from molecular mechanisms to clinical efficacy

  2024cites this paper
• Functional characterization of Large yellow croaker (Larimichthys crocea) PeroxiredoxinIV (PrxIV) gene promoter.

  2024cites this paper
• Analysis of the Differentially Expressed Proteins in Donkey Milk in Different Lactation Stages

  2023cites this paper
• Developmental expression of peroxiredoxin gene family in early embryonic development of Xenopus tropicalis.

  2023cites this paper
• Molecular Mechanisms Related to Responses to Oxidative Stress and Antioxidative Therapies in COVID-19: A Systematic Review

  2022cites this paper
• Peroxiredomin-4 ameliorates lipotoxicity-induced oxidative stress and apoptosis in diabetic cardiomyopathy.

  2021cites this paper
• Anemarrhena asphodeloides modulates gut microbiota and restores pancreatic function in diabetic rats.

  2021cites this paper
• Molecular characterization and functional analysis of peroxiredoxin 4 in grass carp (Ctenopharyngodon idella).

  2021cites this paper
• Redox Enzymes of the Thioredoxin Family as Potential and Novel Markers in Pemphigus

  2021cites this paper
• Association of Prx4, Total Oxidant Status, and Inflammatory Factors with Insulin Resistance in Polycystic Ovary Syndrome

  2021cites this paper
• Vitamins Modulate the Expression of Antioxidant Genes in Progesterone-Treated Pancreatic β Cells: Perspectives for Gestational Diabetes Management

  2020cites this paper
• Cloning and functional characterization of rockfish peroxiredoxin 4 homolog with its innate immune responses

  2019cites this paper
• Peroxiredoxins are important for the regulation of hydrogen peroxide concentrations in ticks and tick cell line.

  2018cites this paper
• Peroxiredoxin 4 (PRDX4): Its critical in vivo roles in animal models of metabolic syndrome ranging from atherosclerosis to nonalcoholic fatty liver disease

  2018cites this paper
• The Combination Of Weak Expression Of PRDX4 And Very High MIB-1 Labelling Index Independently Predicts Shorter Disease-free Survival In Stage I Lung Adenocarcinoma

  2018cites this paper
• Peroxiredoxin 5 is essential for in vitro development of bovine SCNT embryos.

  2017cites this paper
• Recombinant protein transduction domain-Cu/Zn superoxide dismutase alleviates bone cancer pain via peroxiredoxin 4 modulation and antioxidation.

  2017cites this paper
• Peroxiredoxin 4 (PRDX4): Its Critical In Vivo Roles in Animal Models of Metabolic Syndrome Using Our Unique PRDX4 Transgenic Mice

  2017influential citation
• Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases

  2016cites this paper
• Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway

  2016cites this paper
• Overexpression of Peroxiredoxin 4 Affects Intestinal Function in a Dietary Mouse Model of Nonalcoholic Fatty Liver Disease

  2016cites this paper
• Activation of peroxisome proliferator-activated receptor α ameliorates perfluorododecanoic acid-induced production of reactive oxygen species in rat liver

  2015cites this paper
• Protective Effects of L-Carnitine Against Oxidative Injury by Hyperosmolarity in Human Corneal Epithelial Cells.

  2015cites this paper
• Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection

  2014cites this paper
• Periodontitis and Oxidative Stress: Human Studies

  2014cites this paper
• Expression of peroxiredoxin 1 and 4 promotes human lung cancer malignancy.

  2014cites this paper
• Peroxiredoxin 4 Protects Against Nonalcoholic Steatohepatitis and Type 2 Diabetes in a Nongenetic Mouse Model

  2013cites this paper
• PRDX4 (peroxiredoxin 4)

  2013cites this paper
• Effects of hyperhomocysteinemia and betaine-homocysteine S-methyltransferase inhibition on hepatocyte metabolites and the proteome.

  2013cites this paper
• Targeting endogenous antioxidants to prevent cardiovascular diseases.

  2012cites this paper
• Overexpression of Peroxiredoxin 4 Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice

  2012cites this paper