Does propofol definitely improve postoperative cognitive dysfunction?—a review of propofol-related cognitive impairment

Postoperative cognitive dysfunction (POCD) is a common brain function-related complication after surgery. In addition to old age being an independent risk factor, anesthetics are also important predisposing factors. Among them, propofol is the most commonly used intravenous anesthetic in clinical practice. It has a rapid onset, short half-life, and high recovery quality. Many studies report that propofol can attenuate surgery-induced cognitive impairment, however, some other studies reveal that propofol also induces cognitive dysfunction. Therefore, this review summarizes the effects of propofol on the cognition, and discusses possible related mechanisms, which aims to provide some evidence for the follow-up studies.

• Publication year

  2022

• Venue

  Acta Biochimica et Biophysica Sinica

• Publication date

  2022-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.3724/abbs.2022067PMID 35713318PMCID 9828335
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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