Alterations in the volume of thalamic nuclei in patients with schizophrenia and persistent auditory hallucinations

Marta Pérez-Rando,Uriel K.A. Elvira,G. García-Martí,M. Gadea,E. Aguilar,M. Escarti,Mónica Alba Ahulló-Fuster,E. Grasa,I. Corripio,J. Sanjuán,J. Nácher

Published 2022 in NeuroImage: Clinical

ABSTRACT

Highlights • Analysis of structural MRI images using a probabilistic atlas for segmentation of several nuclei of the thalamus.• Comparison of chronic patients with schizophrenia, with and without auditory hallucinations and matched healthy controls.• Volumetric reductions in patients with AH vs controls: Medial geniculate nucleus, anterior pulvinar nucleus and lateral and medial mediodorsal nuclei.• In patients without AH we found reductions in the volume of the pulvinar and mediodorsal nuclei, but not in the medial geniculate nucleus.• Found also some significant correlations between the volume of these nuclei and the total score of the PSYRATS scale.

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