Indium-mediated 1,2-addition of iododifluoromethyl ketones with α, β-unsaturated ketones

No abstract is available for this paper.

• Publication year

  2022

• Venue

  Tetrahedron

• Publication date

  2022-05-01

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1016/j.tet.2022.132855
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Indium-Mediated Reformatsky Reaction of Iododifluoro Ketones with Aldehydes: Preparation of α,α-Difluoro-β-hydroxyketone Derivatives in Water

  2022cited by this paper
• Reversal of Regioselectivity in Nucleophilic Difluoroalkylation of α,β-Enones Employing In Situ-Formed Sterically Encumbered Silylium Catalyst.

  2021cited by this paper
• Enantioselective Indium-Catalyzed Transformations

  2021cited by this paper
• Defluoroalkylation of sp3 C-F Bonds of Industrially Relevant Hydrofluoroolefins.

  2020cited by this paper
• Recent Advances for the Direct Introduction of the CF2Me Moiety

  2019cited by this paper
• Synthesis and antileishmanial activity of fluorinated rhodacyanine analogues: The 'fluorine-walk' analysis.

  2019cited by this paper
• Palladium‐Catalyzed Benzodifluoroalkylation of Alkynes: A Route to Fluorine‐Containing 1,1‐Diarylethylenes

  2018cited by this paper
• Indium‐Mediated Domino Allylation‐Lactonisation Approach: Diastereoselective Synthesis of β‐Carboline C‐3 Tethered α‐Methylene γ‐Butyrolactones

  2018cited by this paper
• Difluorocarbene as a Building Block for Consecutive Bond-Forming Reactions.

  2018cited by this paper
• University of Groningen Catalytic asymmetric alkylation of ketones using organometallic reagents

  2017cited by this paper
• α,α-Difluoro-α-(trimethylsilyl)acetamides as Versatile Reagents for the Preparation of Difluorinated Aldol and Mannich Adducts

  2017cited by this paper
• A general and efficient Lewis acid catalysed Mukaiyama-aldol reaction of difluoroenoxysilanes and ketones.

  2017cited by this paper
• All-carbon quaternary centers in natural products and medicinal chemistry: recent advances

  2016cited by this paper
• Bis(difluoromethyl)trimethylsilicate Anion: A Key Intermediate in Nucleophilic Difluoromethylation of Enolizable Ketones with Me3 SiCF2 H.

  2016cited by this paper
• Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters.

  2016cited by this paper
• Nucleophilic Difluoromethylenation of Ketones Using Diethyl (Difluoro(trimethylsilyl)methyl)phosphonate Mediated by 18-Crown-6 Ether/KOAc.

  2016cited by this paper
• Nucleophilic Iododifluoromethylation of Carbonyl Compounds Using Difluoromethyl 2-Pyridyl Sulfone.

  2016cited by this paper
• Catalytic Synthesis of Enantiopure Chiral Alcohols via Addition of Grignard Reagents to Carbonyl Compounds

  2016cited by this paper
• Indium-mediated Organic Reactions and their Application in Organic Synthesis

  2016cited by this paper
• Catalytic enantioselective construction of quaternary stereocenters: assembly of key building blocks for the synthesis of biologically active molecules.

  2015cited by this paper
• Chiral 1,1-diaryl compounds as important pharmacophores

  2013cited by this paper
• Organoindium reagents: the preparation and application in organic synthesis.

  2013cited by this paper
• Fluorine local environment: from screening to drug design.

  2012cited by this paper
• Enantioselective Reformatsky reaction of ethyl iododifluoroacetate with ketones.

  2012cited by this paper
• Nature of the Intermediates Formed During Indium Mediated Allylation under Barbier Conditions. Spectroscopic and Experimental Data on Allylindium Species

  2011cited by this paper
• Synopsis of some recent tactical application of bioisosteres in drug design.

  2011cited by this paper
• Gold-Catalysed Activation of Epoxides: Application in the Synthesis of Bicyclic Ketals†

  2011cited by this paper
• Making and breaking of Sn-C and In-C bonds in situ: the cases of allyltins and allylindiums.

  2010cited by this paper
• Selectivity Control in 1,2- and 1,4-Additions of Aluminum Organyls to Carbonyl Compounds

  2008cited by this paper
• Recent Progress in the Catalytic Synthesis of Tertiary Alcohols from Ketones with Organometallic Reagents

  2008cited by this paper
• Nucleophilic fluoroalkylation of alpha,beta-enones, arynes, and activated alkynes with fluorinated sulfones: probing the hard/soft nature of fluorinated carbanions.

  2008cited by this paper
• Asymmetric catalysis for the construction of quaternary carbon centres: nucleophilic addition on ketones and ketimines.

  2007cited by this paper
• Rh-catalyzed novel α-fluoroalkylation of α,β-unsaturated ketones and its mechanism

  2007cited by this paper
• Simple synthesis of some unsaturated 1,1-difluoro-2-hydroxyethylphosphonates

  2007cited by this paper
• Fluorine in Pharmaceuticals: Looking Beyond Intuition

  2007cited by this paper
• Enantioselective Catalytic Formation of Quaternary Stereogenic Centers

  2007cited by this paper
• Recent Advances in Indium-Promoted Organic Reactions

  2007cited by this paper
• Advances in indium triflate catalyzed organic syntheses

  2007cited by this paper
• Asymmetric Addition to Ketones: Enantioselective Formation of Tertiary Alcohols

  2006cited by this paper
• Soluble lanthanide salts (LnCl3.2LiCl) for the improved addition of organomagnesium reagents to carbonyl compounds.

  2006cited by this paper
• New Applications of Indium Catalysts in Organic Synthesis

  2004cited by this paper
• Indium- and gallium-mediated carbon-carbon bond-forming reactions in organic synthesis

  2004cited by this paper
• Indium in Organic Synthesis

  2003cited by this paper
• Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues.

  2001cited by this paper
• From Highly Enantioselective Monomeric Catalysts to Highly Enantioselective Polymeric Catalysts: Application of Rigid and Sterically Regular Chiral Binaphthyl Polymers to the Asymmetric Synthesis of Chiral Secondary Alcohols

  1999cited by this paper
• Catalytic Asymmetric Addition of ZnPh2 to Ketones: Enantioselective Formation of Quaternary Stereocenters

  1998cited by this paper
• Planar-Chiral Heterocycles as Ligands in Metal-Catalyzed Processes: Enantioselective Addition of Organozinc Reagents to Aldehydes.

  1997cited by this paper
• Methods for the synthesis of gem-difluoromethylene compounds

  1996cited by this paper
• Synthetic Organoindium Chemistry: What Makes Indium so Appealing?

  1995cited by this paper
• Gem-difluoroallylation of aldehydes and ketones as a convenient route to .alpha.,.alpha.-difluorohomoallylic alcohols

  1991cited by this paper
• Reactions of carbonyl compounds with Grignard reagents in the presence of cerium chloride

  1989cited by this paper
• Indium in organic synthesis: indium-mediated allylation of carbonyl compounds

  1988cited by this paper
• Synthesis of β-Hydroxyesters by Reformatsky Reaction Using Indium Metal

  1988cited by this paper
• Alkylation of enones and ketones using substituted alkyl- and arylaluminum compounds

  1979cited by this paper
• Activated metals. IX. New reformatsky reagent involving activated indium for the preparation of .beta.-hydroxy esters

  1975cited by this paper
• Reactions of Triethylaluminum with α,β-Unsaturated Carbonyl Compounds

  1968cited by this paper

• Electrophilic aromatic substitution using fluorinated isoxazolines at the C5 position via C–F bond cleavage

  2024cites this paper
• Iron-mediated Reformatsky reaction of iododifluoromethyl ketones with aldehydes: Preparation of α,α-difluoro-β-hydroxyketone derivatives

  2023cites this paper