Anti-cancer-prostaglandin-induced cell-cycle arrest and its modulation by an inhibitor of the ATP-dependent glutathione S-conjugate export pump (GS-X pump).

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Biochemical Journal

• Publication date

  1998-12-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1042/BJ3360569PMID 9841867PMCID PMC1219906
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Adjuvant effects of antineoplastic prostaglandins to cisplatin in nude mice bearing human ovarian cancer cells

  2005cited by this paper
• Eicosanoids and Other Bioactive Lipids

  2000cited by this paper
• Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

  1997cited by this paper
• Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR.

  1997cited by this paper
• Cell growth inhibition by antitumor prostaglandin and its modulation by MRP/GS-X pump.

  1997cited by this paper
• Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1

  1997cited by this paper
• Transient induction of the MRP/GS-X pump and gamma-glutamylcysteine synthetase by 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3- nitrosourea in human glioma cells.

  1997cited by this paper
• The GS-X Pump in Plant, Yeast, and Animal Cells: Structure, Function, and Gene Expression

  1997cited by this paper
• Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

  1996cited by this paper
• Frequent coordinated overexpression of the MRP/GS-X pump and gamma-glutamylcysteine synthetase genes in human colorectal cancers.

  1996cited by this paper
• cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats*

  1996cited by this paper
• Prostaglandin A Blocks the Activation of G Phase Cyclin-dependent Kinase without Altering Mitogen-activated Protein Kinase Stimulation (*)

  1996cited by this paper
• Role of p21 in prostaglandin A2-mediated cellular arrest and death.

  1996cited by this paper
• Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2

  1996cited by this paper
• Coordinated Induction of MRP/GS-X Pump and γ-Glutamylcysteine Synthetase by Heavy Metals in Human Leukemia Cells*

  1996cited by this paper
• The retinoblastoma protein and cell cycle control.

  1995cited by this paper
• Principles of CDK regulation

  1995cited by this paper
• The C-terminal Region of p21 Is Involved in Proliferating Cell Nuclear Antigen Binding but Does Not Appear to Be Required for Growth Inhibition (*)

  1995cited by this paper
• Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/CIP1/WAF1.

  1995cited by this paper
• Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA.

  1995cited by this paper
• Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age.

  1994cited by this paper
• The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

  1994cited by this paper
• E2F-dependent regulation of human MYC: trans-activation by cyclins D1 and A overrides tumour suppressor protein functions.

  1994cited by this paper
• Evidence for a p53‐independent pathway for upregulation of SDI1/CIP1/WAF1/P21 RNA in human cells

  1994cited by this paper
• Cdk inhibitors: on the threshold of checkpoints and development.

  1994cited by this paper
• GS-X pump is functionally overexpressed in cis-diamminedichloroplatinum (II)-resistant human leukemia HL-60 cells and down-regulated by cell differentiation.

  1994cited by this paper
• p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21.

  1994cited by this paper
• WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

  1994cited by this paper
• The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

  1994cited by this paper
• Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

  1994cited by this paper
• Functional interactions of the retinoblastoma protein with mammalian D-type cyclins.

  1993cited by this paper
• WAF1, a potential mediator of p53 tumor suppression.

  1993cited by this paper
• p21 is a universal inhibitor of cyclin kinases

  1993cited by this paper
• The role of c-myc in cell growth.

  1993cited by this paper
• The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases.

  1993cited by this paper
• Organic synthesis of prostaglandins: advancing biology.

  1993cited by this paper
• Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line.

  1992cited by this paper
• E2F: a link between the Rb tumor suppressor protein and viral oncoproteins.

  1992cited by this paper
• The ATP-dependent glutathione S-conjugate export pump.

  1992cited by this paper
• Eicosanoids and Other Bioactive Lipids in Cancer and Radiation Injury

  1991cited by this paper
• Purification of an allene oxide synthase and identification of the enzyme as a cytochrome P-450.

  1991cited by this paper
• Molecular mechanisms of sleep‐wake regulation: roles of prostaglandins D2 and E2

  1991cited by this paper
• Conjugation of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 with intracellular glutathione and enhancement of its antiproliferative activity by glutathione depletion.

  1990cited by this paper
• E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.

  1989cited by this paper
• ATP/Mg2+-dependent cardiac transport system for glutathione S-conjugates. A study using rat heart sarcolemma vesicles.

  1989cited by this paper
• Prostaglandins, Leukotrienes, and the Immune Response

  1988cited by this paper
• Site and mechanism of growth inhibition by prostaglandins. IV. Effect of cyclopentenone prostaglandins on cell cycle progression of G1-enriched HeLa S3 cells.

  1988cited by this paper
• Site and mechanism of growth inhibition by prostaglandins. III. Distribution and binding of prostaglandin A2 and delta 12-prostaglandin J2 in nuclei.

  1987cited by this paper
• Site and mechanism of growth inhibition by prostaglandins. II. Temperature-dependent transfer of a cyclopentenone prostaglandin to nuclei.

  1986cited by this paper
• Requirement of a reactive alpha, beta-unsaturated carbonyl for inhibition of tumor growth and induction of differentiation by "A" series prostaglandins.

  1985cited by this paper
• Prostaglandin A compounds as antiviral agents.

  1980cited by this paper
• Reduction of disulfide-containing amines amino acids, and small peptides.

  1976cited by this paper
• The conjugation of prostaglandin A1 and glutathione catalyzed by homogeneous glutathione s-transferases from human and rat liver.

  1975cited by this paper

• Thiol-trapping natural products under the lens of the cysteamine assay: friends, foes, or simply alternatively reversible ligands?

  2020cites this paper
• Thiol-trapping natural products under the lens of the cysteamine assay: friends, foes, or simply alternatively reversible ligands?

  2020cites this paper
• Exposure to xenobiotic chemicals disrupts metabolism , rhythmicity and cell proliferation in Drosophila melanogaster

  2018cites this paper
• Patho)physiological function of the Multidrug Resistance protein MRP1

  2017cites this paper
• Human ABC Transporter ABCC11: Looking Back Pioneers’ Odyssey and Creating a New Path Toward Clinical Application

  2016cites this paper
• Synthesis of Chiral Cyclopentenones.

  2016cites this paper
• Synthesis of biologically relevant molecules

  2015cites this paper
• A-class prostaglandins: early findings and new perspectives for overcoming tumor chemoresistance.

  2012cites this paper
• BCRP (ABCG2) expression, function and regulation in model and intestinal epithelial cells

  2011cites this paper
• ATP-binding cassette efflux transporters in human placenta.

  2011cites this paper
• Modulators of multidrug resistance associated proteins in the management of anticancer and antimicrobial drug resistance and the treatment of inflammatory diseases.

  2010cites this paper
• Direct covalent modification as a strategy to inhibit nuclear factor-kappa B.

  2009cites this paper
• UNIVERSIDADE ESTADUAL PAULISTA "JULIO MESQUITA FILHO" FACULDADE DE CIÊNCIAS AGRÁRIAS E VETERINÁRIAS CÂMPUS DE JABOTICABAL REATIVIDADE DE TECIDOS NEOPLÁSICOS CANINOS À PROTEÍNA ASSOCIADA À RESISTÊNCIA A MÚLTIPLAS DROGAS-1 (MRP1), À GLUTATIONA-S-TRANSFERASE pi (GSTpi) E À PROTEÍNA p53

  2008cites this paper
• Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development.

  2008cites this paper
• MRP class of human ATP binding cassette (ABC) transporters: historical background and new research directions

  2008influential citation
• MODIFICACIÓN DE PROTEÍNAS POR LÍPIDOS ELECTRÓFILOS: SELECTIVIDAD

  2007cites this paper
• Recent developments in the synthesis of prostaglandins and analogues.

  2007cites this paper
• Synthesis and biological evaluation of new cross-conjugated dienone marine prostanoid analogues.

  2004cites this paper
• Punaglandins, chlorinated prostaglandins, function as potent Michael receptors to inhibit ubiquitin isopeptidase activity.

  2004cites this paper
• A rapid access to chiral alkylidene cyclopentenone prostaglandins involving ring-closing metathesis reaction

  2003cites this paper
• Beta-irradiation used for systemic radioimmunotherapy induces apoptosis and activates apoptosis pathways in leukaemia cells

  2003cites this paper
• Role of heme oxygenase‐1 protein in the neuroprotective effects of cyclopentenone prostaglandin derivatives under oxidative stress

  2003cites this paper
• The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

  2003cites this paper
• Beta-irradiation used for systemic radioimmunotherapy induces apoptosis and activates apoptosis pathways in leukaemia cells

  2003cites this paper
• [Neurotrophin-like low molecular weight compounds].

  2002cites this paper
• The medicinal chemistry of multidrug resistance (MDR) reversing drugs.

  2002cites this paper
• Neurite outgrowth-promoting prostaglandins that act as neuroprotective agents against brain ischemia and may enhance recovery of higher neuronal functions

  2002cites this paper
• Activation of the mouse heme oxygenase-1 gene by 15-deoxy-Delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2.

  2002cites this paper
• Activation of the Mouse Heme Oxygenase-1 Gene by 15-Deoxy-Δ12,14-Prostaglandin J2 Is Mediated by the Stress Response Elements and Transcription Factor Nrf2

  2002cites this paper
• Antiproliferative prostaglandins and the MRP/GS-X pump role in cancer immunosuppression and insight into new strategies in cancer gene therapy.

  2001cites this paper
• Energy-dependent export of the 13-oxooctadecadienoic acid-glutathione conjugate from HT-29 cells and plasma membrane vesicles.

  2001cites this paper
• Paclitaxel and SN‐38 Overcome Cisplatin Resistance of Ovarian Cancer Cell Lines by Down‐regulating the Influx and Efflux System of Cisplatin

  2001cites this paper
• Cyclopentenone prostaglandins: New insights on biological activities and cellular targets

  2001cites this paper
• Neurotrophic actions of novel compounds designed from cyclopentenone prostaglandins

  2001cites this paper
• Facilitatory Roles of Novel Compounds Designed from Cyclopentenone Prostaglandins on Neurite Outgrowth‐Promoting Activities of Nerve Growth Factor

  2000cites this paper
• 15-Deoxy-Delta(12,14)-prostaglandin J(2) facilitates thyroglobulin production by cultured human thyrocytes.

  2000cites this paper
• Designed Prostaglandins with Neurotrophic Activities

  2000cites this paper
• Designed cyclopentenone prostaglandin derivatives as neurite outgrowth-promoting compounds for CAD cells, a rat catecholaminergic neuronal cell line of the central nervous system.

  2000cites this paper
• The (patho)physiological functions of the MRP family.

  2000cites this paper
• Universidade Federal do Rio Grande do Sul Instit uto de Ciências Básicas da Saúde Departamento de Fisiolog ia

  2000cites this paper
• 15-Deoxy-Δ12,14-prostaglandin J2facilitates thyroglobulin production by cultured human thyrocytes

  2000cites this paper
• Molecular Design of Prostaglandin Probes in Brain Research: High, Specific Binding to a Novel Prostacyclin Receptor in the Central Nervous System.

  2000cites this paper
• The Human Multidrug Resistance-Associated Protein (MRP) Gene Family: From Biological Function to Drug Molecular Design

  2000cites this paper
• Patho ) physiological function of the Multidrug Resistance protein MRP 1

  2000cites this paper
• Molecular design of glutathione-derived biochemical probes targeting the GS-X pump

  1999cites this paper
• Prostaglandin J2 and its metabolites promote neurite outgrowth induced by nerve growth factor in PC12 cells.

  1999cites this paper
• [35S]S-[5-(4-benzoylphenyl)pentyl]glutathione: a versatile radioligand targeting GS-X pumps with the ability of photoaffinity labeling.

  1999cites this paper