Neogenin1 is a sonic hedgehog target in medulloblastoma and is necessary for cell cycle progression

No abstract is available for this paper.

• Publication year

  2014

• Venue

  International Journal of Cancer

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/ijc.28330PMID 23775842
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999cited by this paper
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  1999cited by this paper
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  1997cited by this paper
• Altered neural cell fates and medulloblastoma in mouse patched mutants.

  1997influential reference
• Sporadic medulloblastomas contain PTCH mutations.

  1997cited by this paper
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  2019cites this paper
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  2019cites this paper
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  2017cites this paper
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  2015cites this paper
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