TGF- (cid:1) mediates PTEN suppression and cell motility through calcium-dependent PKC- (cid:2) activation in pancreatic cancer cells

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Cancer Statistics, 2007

  2007cited by this paper
• RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells.

  2007influential reference
• The Signaling Network of Transforming Growth Factor β1, Protein Kinase Cδ, and Integrin Underlies the Spreading and Invasiveness of Gastric Carcinoma Cells

  2005cited by this paper
• Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity.

  2005cited by this paper
• Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3.

  2003cited by this paper
• Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma.

  2003cited by this paper
• Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1

  2002cited by this paper
• Signal Transductions Induced by Bone Morphogenetic Protein-2 and Transforming Growth Factor-β in Normal Human Osteoblastic Cells*

  2002cited by this paper
• Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways.

  2002cited by this paper
• TGF-beta signaling in cancer--a double-edged sword.

  2001cited by this paper
• TGF-beta signaling in A549 lung carcinoma cells: lipid second messengers.

  2000cited by this paper
• Inhibition of expression of PKC-alpha by antisense mRNA is associated with diminished cell growth and inhibition of amylase secretion by AR4-2J cells.

  1997cited by this paper
• Identification of the protein kinase C isoenzymes in human lung and airways smooth muscle at the protein and mRNA level.

  1997cited by this paper
• Regulation of the Transforming Growth Factor β-responsive Transcription Factor CTF-1 by Calcineurin and Calcium/ Calmodulin-dependent Protein Kinase IV*

  1997cited by this paper
• Frequency of Smad gene mutations in human cancers.

  1997cited by this paper
• TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta.

  1997cited by this paper
• Infrequent Genetic Alterations of the PTEN/MMAC1 Gene in Japanese Patients with Primary Cancers of the Breast, Lung, Pancreas, Kidney, and Ovary

  1997cited by this paper
• Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes.

  1996cited by this paper
• Antiproliferative effects of interferon alpha on human pancreatic carcinoma cell lines are associated with differential regulation of protein kinase C isoenzymes.

  1996cited by this paper
• DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

  1996cited by this paper
• Regulation of protein kinase C and role in cancer biology

  1994cited by this paper
• N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions.

  1994cited by this paper
• Protein kinase C domains involved in interactions with other proteins.

  1994cited by this paper
• Distinct responses of protein kinase C isozymes to c-erbB-2 activation in SKBR-3 human breast carcinoma cells.

  1994cited by this paper
• Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival.

  1993cited by this paper
• Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

  1993influential reference
• Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

  1993cited by this paper
• Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro.

  1993cited by this paper
• Protein kinase C modulation.

  1992cited by this paper
• Role of protein kinase C in the modulation of multidrug resistance: expression of the atypical gamma isoform of protein kinase C does not confer increased resistance to doxorubicin.

  1992cited by this paper
• Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C.

  1992cited by this paper
• Biology of the protein kinase C family

  1989cited by this paper
• Cancer statistics

  1989cited by this paper
• Cloning and expression of multiple protein kinase C cDNAs.

  1986cited by this paper
• Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.

  1986cited by this paper
• The role of protein kinase C in cell surface signal transduction and tumour promotion

  1984cited by this paper

• Novel Soy Peptide CBP: Stimulation of Osteoblast Differentiation via TβRI-p38-MAPK-Depending RUNX2 Activation

  2022influential citation
• Alterations of PTEN and SMAD4 methylation in diagnosis of breast cancer: implications of methyl II PCR assay

  2021cites this paper
• Orai1 Channel Regulates Human-Activated Pancreatic Stellate Cell Proliferation and TGFβ1 Secretion through the AKT Signaling Pathway

  2021cites this paper
• The Role of Calcium Signaling in Regulation of Epithelial-Mesenchymal Transition

  2020cites this paper
• Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression

  2018cites this paper
• Regulation of the tumor suppressor PTEN by natural anticancer compounds

  2017cites this paper
• Nestin expression is upregulated in the fibrotic rat heart and is localized in collagen-expressing mesenchymal cells and interstitial CD31(+)- cells

  2017cites this paper
• Mitochondrial uncouplers inhibit hepatic stellate cell activation

  2012cites this paper
• TGF-β Regulation of Focal Adhesion Proteins and Motility of Premalignant Oral Lesions via Protein Phosphatase 1

  2011cites this paper
• Development -Induced Pancreatic Cancer G12D Kras PTEN Loss Accelerates

  2010cites this paper
• Role of protein kinase C and phosphoinositide 3‐kinase‐Akt in substance P‐induced proinflammatory pathways in mouse macrophages

  2009cites this paper
• TGF-β1 Attenuates Mediator Release and De Novo Kit Expression by Human Skin Mast Cells through a Smad-Dependent Pathway1

  2008cites this paper