Pre-clinical and clinical diagnosis of scrapie by detection of PrP protein in tissues of sheep

No abstract is available for this paper.

• Publication year

  1991

• Venue

  The Veterinary Record

• Publication date

  1991-03-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1136/VR.128.12.271PMID 1674826
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Abnormal fibrils from scrapie-infected brain

  2004cited by this paper
• Two alleles of a neural protein gene linked to scrapie in sheep.

  1990cited by this paper
• Post-mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy.

  1989cited by this paper
• Western blot detection of scrapie-associated fibril protein in tissues outside the central nervous system from preclinical scrapie-infected mice.

  1988cited by this paper
• Detection of scrapie-associated fibrils as an aid to the diagnosis of natural sheep scrapie

  1987cited by this paper
• Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations.

  1986cited by this paper
• Purification of Scrapie Agent from Infected Animal Brains and Raising of Antibodies to the Purified Fraction

  1986cited by this paper
• Antibody to scrapie-associated fibril protein identifies a cellular antigen.

  1986cited by this paper
• Biochemical differences among scrapie-associated fibrils support the biological diversity of scrapie agents.

  1985cited by this paper
• A cellular gene encodes scrapie PrP 27-30 protein.

  1985cited by this paper
• A rapid and efficient method to enrich SAF-protein from scrapie brains of hamsters

  1984cited by this paper
• A protease-resistant protein is a structural component of the scrapie prion.

  1983cited by this paper
• Further purification and characterization of scrapie prions.

  1982cited by this paper
• Identification of a protein that purifies with the scrapie prion.

  1982cited by this paper

• Detection of Pathognomonic Biomarker PrPSc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases

  2020cites this paper
• Compared with the X-Ray Structure and Dynamics of Rabbits

  2015cites this paper
• Scrapie: diagnóstico por imuno-histoquímica, caracterização de surtos e genótipos em ovinos no brasil

  2013cites this paper
• Sensitivity and specificity of a commercial BSE kit for the detection of ovine scrapie.

  2013cites this paper
• Molecular dynamics studies on the NMR and X-ray structures of rabbit prion proteins.

  2013cites this paper
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  2012cites this paper
• Detection of PrPSc in lung and mammary gland is favored by the presence of Visna/maedi virus lesions in naturally coinfected sheep

  2010cites this paper
• Identification of Single Nucleotide Polymorphisms in PRNP Gene of Korean Native Goats

  2009cites this paper
• Active and passive surveillance of bovine spongiform encephalopathy in Bangladesh

  2009influential citation
• High incidence of subclinical infection of lymphoid tissues in scrapie-affected sheep flocks

  2008cites this paper
• Are scrapie-susceptible sheep more productive?

  2007cites this paper
• ENCEFALOPATIAS ESPONGIFORME TRANSMISSÍVEIS E CONSIDERAÇÕES SOBRE O AGENTE ETIOLÓGICO (Transmissibles spongiform encephalopathies and considerations about the etiology)

  2006cites this paper
• Postmortem diagnosis of preclinical and clinical scrapie in sheep by the detection of disease-associated PrP in their rectal mucosa

  2006cites this paper
• Identification of an allelic variant of the goat PrP gene associated with resistance to scrapie.

  2006cites this paper
• Detection of PrP(Sc) in rectal biopsy and necropsy samples from sheep with experimental scrapie.

  2006cites this paper
• PrPSc accumulation in fetal cotyledons of scrapie-resistant lambs is influenced by fetus location in the uterus.

  2006cites this paper
• Entwicklung und Anwendung eines enzymimmunologischen Verfahrens zum Nachweis von zellulärem Prion Protein bei Wiederkäuern

  2005cites this paper
• Improvement of PrPSc-detection in mouse spleen early at the preclinical stage of scrapie with collagenase-completed tissue homogenization and Sarkosyl-NaCl extraction of PrPSc

  2005cites this paper
• Rapid PrPSc Detection in Lymphoid Tissue and Application to Scrapie Surveillance of Fallen Stock in Japan: Variable PrPSc Accumulation in Palatal Tonsil in Natural Scrapie

  2005cites this paper
• Characterisation of antisera raised against species-specific peptide sequences from scrapie-associated fibril protein and their application for post-mortem immunodiagnosis of spongiform encephalopathies

  2005cites this paper
• Evaluation of an oligonucleotide ligation assay for detection of mutations in HIV-1 subtype C individuals who have high level resistance to nucleoside reverse transcriptase inhibitors and non-nucleoside reverse transcriptase inhibitors.

  2005cites this paper
• Approaches to Scrapie diagnosis by applying immunohistochemistry and rapid tests on central nervous and lymphoreticular systems.

  2005cites this paper
• A specific RFLP type associated with the occurrence of sheep scrapie in Japan

  2005cites this paper
• Detection of PrPSc in sheep at the preclinical stage of scrapie and its significance for diagnosis of insidious infection

  2005cites this paper
• Detection of PrPsc on Lymphoid Tissues from Naturally Affected Scrapie Animals: Comparison of Three Visualization Systems

  2004influential citation
• Prion Diseases and the Spleen

  2004cites this paper
• Western Immunoblotting Techniques for the Study of Transmissible Spongiform Encephalopathies

  2004cites this paper
• Monte Carlo simulation of surveillance strategies for scrapie in Norwegian sheep.

  2003cites this paper
• Detection of disease-specific PrP in the distal ileum of cattle exposed orally to the agent of bovine spongiform encephalopathy

  2003cites this paper
• Scrapie and chronic wasting disease.

  2003cites this paper
• Chronic wasting disease in deer and elk in North America.

  2002cites this paper
• Immunohistochemical detection of Prion protein (PrP-Sc) and epidemiological study of BSE in Korea.

  2001cites this paper
• PrP-C and PrP-Sc at the Fetal-Maternal Interface*

  2001cites this paper
• Prion detection by immunological methods

  2001cites this paper
• Immunohistochemical Detection of Scrapie Prion Proteins in Clinically Normal Sheep in Pennsylvania

  2001cites this paper
• Ovine scrapie. New tools for control of an old disease.

  2001cites this paper
• Bovine spongiform encephalopathy--food safety implications.

  2001cites this paper
• Analysis of transient gene expression in ovine cells : a role for the PrP gene 3'UTR

  2000cites this paper
• Pathogenesis of natural scrapie in sheep.

  2000cites this paper
• Preclinical Diagnosis of Scrapie by Immunohistochemistry of Third Eyelid Lymphoid Tissue

  2000cites this paper
• Japanese scrapie cases.

  2000cites this paper
• Suitability of protuberances on the third eyelids of sheep as a biopsy site for lymphoid follicles

  2000cites this paper
• Protease-resistant prion protein in brain and lymphoid organs of sheep within a naturally scrapie-infected flock.

  2000cites this paper
• Detection methods of possible prion contaminants in collagen and gelatin

  1999cites this paper
• Maladies à prion ou encéphalopathies spongiformes transmissibles

  1999cites this paper
• Scrapie-associated prion protein in the gastrointestinal tract of sheep with natural scrapie.

  1999cites this paper
• Immunolocalization of the prion protein in scrapie affected rodent retinas.

  1999cites this paper
• The Immunodetection of the Abnormal Isoform of Prion Protein

  1999cites this paper
• Scrapie transmission in Britain: a recipe for a mathematical model

  1999cites this paper
• Sensitivity of the Western blot detection of prion protein PrPres in natural sheep scrapie.

  1998cites this paper
• Preclinical detection of PrPSc in nictitating membrane lymphoid tissue of sheep

  1998cites this paper
• Scrapie infectivity and proteinase K-resistant prion protein in sheep placenta, brain, spleen, and lymph node: implications for transmission and antemortem diagnosis.

  1998cites this paper
• The distribution of scrapie-associated fibrils in neural and non-neural tissues of advanced clinical cases of natural scrapie in sheep.

  1998cites this paper
• An immunological approach to prion diseases.

  1998cites this paper
• The 3' untranslated region of the PrP gene

  1997cites this paper
• Immunodetection of PrPSc in spleens of some scrapie-infected sheep but not BSE-infected cows.

  1997influential citation
• Control of scrapie eventually possible?

  1997cites this paper
• Alternative usage of exon 1 of bovine PrP mRNA.

  1997cites this paper
• Sensitive enzyme-linked immunosorbent assay for detection of PrP(Sc) in crude tissue extracts from scrapie-affected mice.

  1997cites this paper
• Biochemical properties of protease resistant prion proteinPrPsc in natural sheep scrapie

  1997cites this paper
• Immunohistochemical detection of prion protein in lymphoid tissues of sheep with natural scrapie

  1996cites this paper
• Protease-resistant PrP deposition in brain and non-central nervous system tissues of a murine model of bovine spongiform encephalopathy.

  1996cites this paper
• Bovine spongiform encephalopathy--the beginning of the end?

  1996cites this paper
• Immunoreactivity of specific epitopes of PrPSc is enhanced by pretreatment in a hydrated autoclave

  1996cites this paper
• [Bovine spongiform encephalopathy. Second update of data collected since the report of February 6, 1996].

  1996cites this paper
• Aspects cliniques des encéphalopathies spongiformes transmissibles animales

  1996cites this paper
• Scrapie and bovine spongiform encephalopathy: immunological properties and diagnosis for food products

  1996cites this paper
• Analysis of Risk Factors and Active Surveillance for BSE in Argentina

  1996cites this paper
• Risk assessment and surveillance for bovine spongiform encephalopathy (BSE) in Argentina

  1996cites this paper
• Scrapie: Studies on Vertical and Horizontal Transmission

  1996cites this paper
• Allelic frequencies of an ovine scrapie susceptibility gene

  1996cites this paper
• Scrapie: recent trends.

  1996cites this paper
• Amino acid polymorphisms of PrP with reference to onset of scrapie in Suffolk and Corriedale sheep in Japan.

  1995cites this paper
• A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep.

  1995cites this paper
• [Scrapie in sheep and transmissible encephalopathy of the mink].

  1995cites this paper
• Effect of Sinc genotype, agent isolate and route of infection on the accumulation of protease-resistant PrP in non-central nervous system tissues during the development of murine scrapie.

  1994cites this paper
• Detection of Prion Protein in Formalin-Fixed Brain by Hydrated Autoclaving Immunohistochemistry for the Diagnosis of Scrapie in Sheep

  1994cites this paper
• Diversity of clinical signs in natural scrapie cases occurring in Japan.

  1994cites this paper
• The Significance of PrPSc Detection for the Diagnosis of Insidious Scrapie

  1994cites this paper
• [Transmissible animal spongiform encephalopathies. Epidemiologic aspects].

  1994cites this paper
• Animal spongiform encephalopathies--an update. Part 1. Scrapie and lesser known animal spongiform encephalopathies.

  1994cites this paper
• Survey of natural scrapie in Japan: analysis of RFLP types of the PrP gene and detection of PrPSc mainly in Suffolk sheep.

  1994cites this paper
• Les encéphalopathies spongiformes transmissibles animales. Aspects épidémiologiques

  1994cites this paper
• Correlation between the results of a histopathological examination and the detection of abnormal brain fibrils in the diagnosis of bovine spongiform encephalopathy.

  1994cites this paper
• SCID mouse spleen does not support scrapie agent replication.

  1994cites this paper
• Isolation of Scrapie Agent from the Placenta of Sheep with Natural Scrapie in Japan

  1993cites this paper
• Immunohistochemical Detection of Prion Protein in Sheep with Scrapie

  1993cites this paper
• Familial scrapie cases with shortened incubation periods.

  1993cites this paper
• The biology and molecular biology of scrapie-like diseases.

  1993cites this paper
• Spongiform encephalopathy in a herd of greater kudu (Tragelaphus strepsiceros): epidemiological observations

  1993cites this paper
• Bovine spongiform encephalopathy and Australia.

  1992cites this paper
• Nearly ubiquitous tissue distribution of the scrapie agent precursor protein

  1992cites this paper
• Feline spongiform encephalopathy: fibril and PrP studies

  1992cites this paper
• Are Sinc and the PrP gene congruent? Evidence from PrP gene analysis in Sinc congenic mice.

  1992cites this paper
• Diagnostic implications of detection of proteinase K-resistant protein in spleen, lymph nodes, and brain of sheep.

  1992cites this paper
• Total CK and CK-BB activity in serum from sheep with scrapie.

  1992cites this paper
• Comparative sequence analysis and expression of bovine PrP gene in mouse L-929 cells

  1992cites this paper
• Immunodetection of a disease specific PrP fraction in scrapie-affected sheep and BSE-affected cattle

  1992cites this paper
• Feline spongiform encephalopathy

  1992cites this paper
• Feline spongiform encephalopathy

  1991cites this paper