Regulation of the subcellular trafficking of CD36, a major determinant of cardiac fatty acid utilization.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Biochimica et Biophysica Acta

• Publication date

  2016-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.bbalip.2016.04.008PMID 27090938
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Extremely rapid increase in fatty acid transport and intramyocellular lipid accumulation but markedly delayed insulin resistance after high fat feeding in rats

  2015cited by this paper
• Insight into the mechanism of lipids binding and uptake by CD36 receptor

  2015cited by this paper
• Molecular Mechanisms for the Regulation of Insulin-Stimulated Glucose Uptake by Small Guanosine Triphosphatases in Skeletal Muscle and Adipocytes

  2014cited by this paper
• Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism.

  2014cited by this paper
• Control of Myocardial Fatty Acid Uptake

  2014cited by this paper
• Signal transduction meets vesicle traffic: the software and hardware of GLUT4 translocation.

  2014cited by this paper
• Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36

  2013cited by this paper
• Cardiomyocyte-specific ablation of CD36 improves post-ischemic functional recovery.

  2013cited by this paper
• Differential Translocation of the Fatty Acid Transporter, FAT/CD36, and the Glucose Transporter, GLUT4, Coordinates Changes in Cardiac Substrate Metabolism During Ischemia and Reperfusion

  2013cited by this paper
• CD36 and taste of fat

  2012cited by this paper
• Insulin and AMPK regulate FA translocase/CD36 plasma membrane recruitment in cardiomyocytes via Rab GAP AS160 and Rab8a Rab GTPase

  2012cited by this paper
• Fatty acid transport proteins, implications in physiology and disease.

  2012cited by this paper
• Overexpression of Vesicle-associated Membrane Protein (VAMP) 3, but Not VAMP2, Protects Glucose Transporter (GLUT) 4 Protein Translocation in an in Vitro Model of Cardiac Insulin Resistance*

  2012cited by this paper
• CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes.

  2012cited by this paper
• Regulation of glucose transport by insulin: traffic control of GLUT4

  2012cited by this paper
• Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart.

  2011cited by this paper
• Post-translational modifications, a key process in CD36 function: lessons from the spontaneously hypertensive rat heart.

  2011cited by this paper
• Changes in Cardiac Substrate Transporters and Metabolic Proteins Mirror the Metabolic Shift in Patients with Aortic Stenosis

  2011cited by this paper
• Increased CD36 expression in middle-aged mice contributes to obesity-related cardiac hypertrophy in the absence of cardiac dysfunction

  2011cited by this paper
• Absence of fatty acid transporter CD36 protects against Western-type diet-related cardiac dysfunction following pressure overload in mice.

  2011cited by this paper
• Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells.

  2011cited by this paper
• Requirement for distinct vesicle-associated membrane proteins in insulin- and AMP-activated protein kinase (AMPK)-induced translocation of GLUT4 and CD36 in cultured cardiomyocytes

  2010cited by this paper
• Intramyocellular lipid accumulation is associated with permanent relocation ex vivo and in vitro of fatty acid translocase (FAT)/CD36 in obese patients

  2010cited by this paper
• Differential regulation of cardiac glucose and fatty acid uptake by endosomal pH and actin filaments.

  2010influential reference
• Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease.

  2010cited by this paper
• Lipotoxicity in the heart.

  2010cited by this paper
• The Human Scavenger Receptor CD36

  2009cited by this paper
• Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates.

  2009cited by this paper
• Additive effects of insulin and muscle contraction on fatty acid transport and fatty acid transporters, FAT/CD36, FABPpm, FATP1, 4 and 6

  2009cited by this paper
• CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior

  2009cited by this paper
• Munc18c is not rate-limiting for glucose and long-chain fatty acid uptake in the heart

  2009cited by this paper
• Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts.

  2008cited by this paper
• What are the Biochemical Mechanisms Responsible for Enhanced Fatty Acid Utilization by Perfused Hearts from Type 2 Diabetic db/db Mice?

  2008cited by this paper
• Disordered lipid metabolism and the pathogenesis of insulin resistance.

  2007cited by this paper
• CD36 Deficiency Rescues Lipotoxic Cardiomyopathy

  2007cited by this paper
• Fatty acid transport proteins

  2007cited by this paper
• Is membrane transport of FFA mediated by lipid, protein, or both? Mechanisms and regulation of protein-mediated cellular fatty acid uptake: molecular, biochemical, and physiological evidence.

  2007cited by this paper
• Mechanisms responsible for enhanced fatty acid utilization by perfused hearts from type 2 diabetic db/db mice

  2007cited by this paper
• A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism.

  2007cited by this paper
• FIP2 and Rip11 specify Rab11a-mediated cellular distribution of GLUT4 and FAT/CD36 in H9c2-hIR cells.

  2007cited by this paper
• Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification

  2007cited by this paper
• AMPK-mediated increase in myocardial long-chain fatty acid uptake critically depends on sarcolemmal CD36.

  2007cited by this paper
• Evidence for concerted action of FAT/CD36 and FABPpm to increase fatty acid transport across the plasma membrane.

  2007cited by this paper
• CD36: implications in cardiovascular disease.

  2007cited by this paper
• New insights into the roles of proteins and lipids in membrane transport of fatty acids.

  2007cited by this paper
• Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart.

  2006cited by this paper
• AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B.

  2006cited by this paper
• Characterization of the Role of the Rab GTPase-activating Protein AS160 in Insulin-regulated GLUT4 Trafficking*

  2005cited by this paper
• Myocardial substrate metabolism in the normal and failing heart.

  2005cited by this paper
• The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR

  2005cited by this paper
• Fatty Acid Translocase/CD36 Deficiency Does Not Energetically or Functionally Compromise Hearts Before or After Ischemia

  2004cited by this paper
• Carnitine palmitoyltransferases 1 and 2: biochemical, molecular and medical aspects.

  2004cited by this paper
• COP and clathrin-coated vesicle budding: different pathways, common approaches.

  2004cited by this paper
• Insulin stimulates fatty acid transport by regulating expression of FAT/CD36 but not FABPpm.

  2004cited by this paper
• Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese zucker rats.

  2004cited by this paper
• Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling.

  2003cited by this paper
• Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake

  2002cited by this paper
• Lipotoxic diseases.

  2002cited by this paper
• Metabolic plasticity and the promotion of cardiac protection in ischemia and ischemic preconditioning.

  2002cited by this paper
• The fatty acid translocase (FAT)/CD36 and the glucose transporter GLUT4 are localized in different cellular compartments in rat cardiac muscle.

  2002cited by this paper
• Control of mitochondrial beta-oxidation flux.

  2002cited by this paper
• Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

  2001cited by this paper
• Role of SNAP23 in Insulin-induced Translocation of GLUT4 in 3T3-L1 Adipocytes

  2000cited by this paper
• Fatty acid import into mitochondria.

  2000cited by this paper
• Acute Regulation of Fatty Acid Uptake Involves the Cellular Redistribution of Fatty Acid Translocase*

  2000cited by this paper
• A conformational switch in syntaxin during exocytosis: role of munc18

  1999cited by this paper
• Protein-mediated palmitate uptake and expression of fatty acid transport proteins in heart giant vesicles.

  1999cited by this paper
• Impaired long-chain fatty acid utilization by cardiac myocytes isolated from mice lacking the heart-type fatty acid binding protein gene.

  1999cited by this paper
• Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM

  1997cited by this paper
• Molecular mechanism of cellular uptake and intracellular translocation of fatty acids.

  1997cited by this paper
• Uptake and metabolism of palmitate by isolated cardiac myocytes from adult rats: involvement of sarcolemmal proteins.

  1997cited by this paper
• Dissociation of long and very long chain fatty acids from phospholipid bilayers.

  1996cited by this paper
• CD36 Is Palmitoylated on Both N- and C-terminal Cytoplasmic Tails*

  1996cited by this paper
• Fatty acid flip-flop in phospholipid bilayers is extremely fast.

  1995cited by this paper
• Association and coexpression of fatty-acid-binding protein and glycoprotein CD36 in the bovine mammary gland.

  1995cited by this paper
• ASSOCIATION AND COEXPRESSION OF FATTY-ACID-BINDING PROTEIN AND GLYCOPROTEIN CD36 IN THE BOVINE MAMMARY GLAND

  1995cited by this paper
• Unbound free fatty acid levels in human serum.

  1995cited by this paper
• Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein.

  1994cited by this paper
• Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart.

  1993cited by this paper
• Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36.

  1993cited by this paper
• On the mechanism of long chain fatty acid transport in cardiomyocytes as facilitated by cytoplasmic fatty acid-binding protein.

  1993cited by this paper
• Malonyl-CoA metabolism in cardiac myocytes and its relevance to the control of fatty acid oxidation.

  1993cited by this paper
• Solubility of long-chain fatty acids in phosphate buffer at pH 7.4.

  1992cited by this paper
• Fatty acid uptake by isolated rat heart myocytes represents a carrier-mediated transport process.

  1988cited by this paper
• Metabolism of the human heart. II. Studies on fat, ketone and amino acid metabolism.

  1954cited by this paper
• Cellular and Molecular Life Sciences REVIEW Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes

  year unknowncited by this paper
• O R I G I N a L I N V E S T I G a T I O N Open Access

  year unknowncited by this paper

• PPARα-CD36-CAV1-mediated docosahexaenoic acid (DHA) uptake promotes muscle fiber development in grass carp (Ctenopharyngodon idellus)

  2026cites this paper
• Insulin regulates lymphatic endothelial integrity via palmitoylation

  2025cites this paper
• CROTONALDEHDE ORAL EXPOSURE DISRUPT CARDIAC ENERGY METABOLISM AND INDUCES OXIDATIVE STRESS VIA DOWN-REGULATION OF NRF-2 AND UP-REGULATION OF PPARα.

  2025cites this paper
• Palmitoylation-dependent modulation of CD36 trafficking and signaling integrates lipid uptake with metabolic disease pathogenesis.

  2025cites this paper
• Linking mitochondria, fatty acids, and hematopoietic stem cell expansion during infection: implications for aging and metabolic diseases

  2025cites this paper
• Phenome-wide Mendelian randomization identifying circulating proteins for cardiovascular traits in populations of African ancestry

  2025cites this paper
• Diabetes mellitus and Alzheimer's disease: Vacuolar adenosine triphosphatase as a potential link

  2024cites this paper
• AS160 is a lipid-responsive regulator of cardiac Ca2+ homeostasis by controlling lysophosphatidylinositol metabolism and signaling

  2024cites this paper
• Comparative analysis of Scarb1 and Cd36 in grass carp (Ctenopharyngodon idellus): Implications for DHA uptake.

  2024cites this paper
• miR-1268a Regulates Fatty Acid Metabolism by Targeting CD36 in Angiotensin II-induced Heart Failure

  2024cites this paper
• Impact of Hydroxytyrosol-Rich Extract Supplementation in a High-Fat Diet on Gilthead Sea Bream (Sparus aurata) Lipid Metabolism

  2024cites this paper
• Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis

  2024cites this paper
• CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease.

  2023cites this paper
• Nutrient sensors and their crosstalk

  2023cites this paper
• Strategy for Pre-Clinical Development of Active Targeting MicroRNA Oligonucleotide Therapeutics for Unmet Medical Needs

  2023cites this paper
• Post-translational palmitoylation of metabolic proteins

  2023cites this paper
• Role of STIM1 in the Regulation of Cardiac Energy Substrate Preference

  2023cites this paper
• The activated CD36-Src axis promotes lung adenocarcinoma cell proliferation and actin remodeling-involved metastasis in high-fat environment

  2023cites this paper
• The involvement of FATP1 regulating skeletal muscle fat deposition in stressed broilers was affected by fatty acid substrates

  2022cites this paper
• PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem-cell-derived cardiomyocytes.

  2022cites this paper
• CD36 inhibition partially attenuates myocardial injury in diabetic rats with ischemic postconditioning

  2022cites this paper
• Pol-miR-150 regulates anti-bacterial and viral infection in Japanese flounder (Paralichthys olivaceus) via the lysosomal protein LMP2L.

  2021cites this paper
• Effects of docosahexaenoic acid or arachidonic acid supplementation on gene expression and contractile force of rat cardiomyocytes in primary culture

  2021cites this paper
• Cardiac Metabolism and Contractile Function in Mice with Reduced Trans-Endothelial Fatty Acid Transport

  2021influential citation
• PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

  2021cites this paper
• The role of CD36 in cardiovascular disease

  2020cites this paper
• Lipid oversupply induces CD36 sarcolemmal translocation via dual modulation of PKCζ and TBC1D1: an early event prior to insulin resistance

  2020cites this paper
• Spatiotemporal dynamic monitoring of fatty acid–receptor interaction on single living cells by multiplexed Raman imaging

  2020cites this paper
• Metabolic Modulation to Treat Cardiac Diseases: Role for Membrane Substrate Transporters

  2020cites this paper
• CD36 (SR-B2) as a Target to Treat Lipid Overload-Induced Cardiac Dysfunction

  2020cites this paper
• Dietary fatty acids and CD36-mediated cholesterol homeostasis: potential mechanisms

  2020cites this paper
• The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle via Fatty Acid Transporter SLC27A4/FATP4

  2020cites this paper
• Dyslipidemia in Kidney Disorders: Perspectives on Mitochondria Homeostasis and Therapeutic Opportunities

  2020cites this paper
• Putative Role of Protein Palmitoylation in Cardiac Lipid-Induced Insulin Resistance

  2020cites this paper
• Fluorescent labelling of membrane fatty acid transporter CD36 (SR-B2) in the extracellular loop

  2019cites this paper
• Cardiac manifestations of inherited metabolic disease linked to cellular metabolism of vitamin B12 : study in two murine models of invalidation of Mtr and MMACHC genes

  2019cites this paper
• Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease

  2019cites this paper
• Enterotoxigenic Escherichia coli Interferes FATP4-Dependent Long-Chain Fatty Acid Uptake of Intestinal Epithelial Enterocytes via Phosphorylation of ERK1/2-PPARγ Pathway

  2019cites this paper
• Fatty Acid Uptake by the Heart During Fasting

  2019cites this paper
• Dynamic role of the transmembrane glycoprotein CD36 (SR-B2) in cellular fatty acid uptake and utilization

  2018cites this paper
• Analysis of Cell Type-Specific Effects of MicroRNA-92a Provides Novel Insights Into Target Regulation and Mechanism of Action

  2018cites this paper
• Lysosomes Mediate Benefits of Intermittent Fasting in Cardiometabolic Disease: The Janitor Is the Undercover Boss.

  2018cites this paper
• G protein-coupled receptor kinase 2 contributes to impaired fatty acid metabolism in the failing heart.

  2018cites this paper
• Myocardial fatty acid uptake through CD36 is indispensable for sufficient bioenergetic metabolism to prevent progression of pressure overload-induced heart failure

  2018cites this paper
• Endothelial cell CD36 optimizes tissue fatty acid uptake

  2018cites this paper
• C1q/TNF-&agr;–Related Protein 1 (CTRP1) Maintains Blood Pressure Under Dehydration Conditions

  2018cites this paper
• Acute and Chronic Effects of Protein Kinase-D Signaling on Cardiac Energy Metabolism

  2018cites this paper
• Molecular Regulation of Fatty Acid Oxidation in Skeletal Muscle during Aerobic Exercise.

  2018cites this paper
• Molecular cloning and gene/protein expression of FAT/CD36 from grass carp (Ctenopharyngodon idella) and the regulation of its expression by dietary energy

  2017cites this paper
• Tet38 Efflux Pump Affects Staphylococcus aureus Internalization by Epithelial Cells through Interaction with CD36 and Contributes to Bacterial Escape from Acidic and Nonacidic Phagolysosomes CELLULAR MICROBIOLOGY: PATHOGEN-HOST CELL MOLECULAR INTERACTIONS

  2017cites this paper
• Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans.

  2017cites this paper
• Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system

  2017cites this paper
• Energetic metabolism in cardiomyocytes: molecular basis of heart ischemia and arrhythmogenesis

  2017cites this paper
• From fat to FAT (CD36/SR-B2): Understanding the regulation of cellular fatty acid uptake.

  2017cites this paper
• Preface to the BBA special issue "heart lipid metabolism".

  2016cites this paper
• Tet38 Efflux Pump Affects Staphylococcus aureus Internalization by Epithelial Cells through Interaction with CD36 and Contributes to Bacterial Escape from Acidic and Nonacidic Phagolysosomes

  2016cites this paper
• Signaling pathways involved in cardiac energy metabolism

  2016cites this paper