Coronin 1C restricts endosomal branched actin to organize ER contact and endosome fission

ER contact sites define the position of endosome bud fission during actin-dependent cargo sorting. Striepen Voeltz show that COR1C confines actin at endosome bud necks. Depleting COR1C and its paralogs causes ARP2/3-dependent actin extension along the bud, resulting in loss of ER contact, and blocks endosome fission.

• Publication year

  2022

• Venue

  Journal of Cell Biology

• Publication date

  2022-07-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.202110089PMID 35802042PMCID 9274145
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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