The sodium‐glucose co‐transporter‐2 inhibitor ertugliflozin modifies the signature of cardiac substrate metabolism and reduces cardiac mTOR signalling, endoplasmic reticulum stress and apoptosis

J. Moellmann,P. A. Mann,B. Kappel,F. Kahles,B. Klinkhammer,P. Boor,R. Kramann,B. Ghesquière,C. Lebherz,N. Marx,M. Lehrke

Published 2022 in Diabetes, obesity and metabolism

ABSTRACT

To investigate cardiac signalling pathways connecting substrate utilization with left ventricular remodelling in a murine pressure overload model.

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