Recent trends in studies of biomolecular phase separation

Biomolecular phase separation has recently attracted broad in-terest, due to its role in the spatiotemporal compartmentalization of living cells. It governs the formation, regulation, and dissociation of biomolecular condensates, which play multiple roles in vivo, from activating specific biochemical reactions to organizing chromatin. Interestingly, biomolecular phase separation seems to be a mainly passive process, which can be ex-plained by relatively simple physical principles and reproduced in vitro with a minimal set of components. This Mini review focuses on our current understanding of the fundamental principles of biomolecular phase separation and the recent progress in the research on this topic.

• Publication year

  2022

• Venue

  BMB Reports

• Publication date

  2022-07-26

• Fields of study

  Biology, Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.5483/BMBRep.2022.55.8.101PMID 35880435PMCID 9442351
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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