Early Changes in Striatal Activity and Motor Kinematics in a Huntington's Disease Mouse Model

Huntington's disease is a progressive neurodegenerative disorder with no disease‐modifying treatments. Patients experience motor, cognitive, and psychiatric disturbances, and the dorsal striatum is the main target of neurodegeneration. Mouse models of Huntington's disease show altered striatal synaptic signaling in vitro, but how these changes relate to behavioral deficits in vivo is unclear.

• Publication year

  2022

• Venue

  Movement Disorders

• Publication date

  2022-07-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/mds.29168PMID 35880748PMCID 9796416
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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