CASE REPORT: AUTOIMMUNE PROGESTERONE DERMATITIS

C. Hieu

Published 2022 in Journal of Clinical Case Reports Medical Images and Health Sciences

ABSTRACT

Autoimmune progesterone dermatitis (APD) is a rare cyclic premenstrual reaction to progesterone produced during the luteal phase of the menstrual cycle. The clinical symptoms of the APD overlap with other forms of dermatosis such as erythema multiforme, eczema, fixed drug eruption, urticaria, and angioedema. APD symptoms usually develop in 3 to 10 days before the menstruation and resolve in 1 to 2 days after the menstruation ceases. Eczema developed on body of a 22-year-old female 7 days prior to her menstrual period. She was diagnosed with allergic contact dermatitis and prescribed with topical steroids. Her skin conditions did not improve and were associated with her menstrual period. An intradermal test using progesterone was performed, which was positive. She was treated with oral danazol and the symptoms were

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