Assessment of Framingham Risk score and Serum Leptin in Patients with Skin Tag

Skin tags are common dermatological lesions that have been linked to metabolic syndrome, which includes diabetes, obesity, and hypertension, as well as cardiovascular disease. Increased adipose deposition and serum leptin levels may be associated with skin tags (STs). The relationship between serum lipid profile and serum leptin levels in patients with skin tags and the Framingham risk score was investigated. The Framingham risk score (FRS) is a method to calculate the likelihood of getting cardiovascular disease (CVD) during a 10-year period (CVD). The current study was carried out on 60 participants; 30 patients with STs and 30 apparently healthy as controls. Serum lipid profile and serum leptin were measured. There was Statistically significant difference of serum leptin level between skin tag (22.6±16.4 ng/ml) group and control (13.23±10.14 ng/ml) and cholesterol also showing significant difference between skin tag disease group (183.3±37.12 mg/dl) and the control group (155.6±21.86 mg/dl). Other parameters Low Density Lipoprotein (LDL), Triglycerides (TG) and non-High-Density Lipoprotein, cholesterol (non-HDL) show no significant difference between the two groups. An assessment was performed to differentiate between skin tag and Framingham risk score. It was found that 70% of patients are in high and moderate risk group. The present study found association between skin tag patients and Framingham risk score.

• Publication year

  2022

• Venue

  Arab Journal of Nuclear Sciences and Applications

• Publication date

  2022-10-12

• Fields of study

  Not labeled

• Identifiers
  DOI 10.21608/ajnsa.2022.145911.1605
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Obesity and Skin Problems

  2021cited by this paper
• The Important Role of Leptin in Modulating the Risk of Dermatological Diseases

  2021cited by this paper
• The role of leptin in selected skin diseases

  2020cited by this paper
• Improved Framingham Risk Scores of Patients with Type 2 Diabetes Mellitus in the Beijing Community: A 10-Year Prospective Study of the Effects of Multifactorial Interventions on Cardiovascular Risk Factors (The Beijing Communities Diabetes Study 22)

  2020cited by this paper
• Cross-sectional study of the association between skin tags and vascular risk factors in a bariatric clinic-based cohort of Irish adults with morbid obesity

  2020cited by this paper
• Correlation of serum lipid profile with leptin levels of skin tags patients

  2019cited by this paper
• Goals of non-high density lipoprotein cholesterol need to be adjusted in Chinese acute coronary syndrome patients: Findings from the CCC-ACS project.

  2019cited by this paper
• Analysis of Serum Leptin Levels in Skin Tag Patients

  2019cited by this paper
• Comparison Between Metabolic Syndrome and the Framingham Risk Score as Predictors of Cardiovascular Diseases Among Kazakhs in Xinjiang

  2018cited by this paper
• The Correlation between Body Mass Index with the Occurrence of Skin Tag

  2017cited by this paper
• Longitudinal Impact of Smoking and Smoking Cessation on Inflammatory Markers of Cardiovascular Disease Risk

  2017cited by this paper
• Role of Coronary Artery Calcium Scoring in Detection of Coronary Artery Disease according to Framingham Risk Score in Populations with Low to Intermediate Risks

  2016cited by this paper
• Assessment of Various Biochemical Parameters and BMI in Patients with Skin Tags.

  2016cited by this paper
• Relationship of Cigarette Smoking With Inflammation and Subclinical Vascular Disease: The Multi-Ethnic Study of Atherosclerosis

  2015cited by this paper
• Predicted 10-year risk of cardiovascular disease among Canadian adults using modified Framingham Risk Score in association with dietary intake.

  2015cited by this paper
• Leptin resistance in obesity: An epigenetic landscape.

  2015cited by this paper
• Applying the Framingham risk score for prediction of metabolic syndrome: The Kerman Coronary Artery Disease Risk Study, Iran

  2015cited by this paper
• Assessment of BMI, Serum Leptin Levels and Lipid Profile in Patients with Skin Tags.

  2014cited by this paper
• Acrochordons as a Cutaneous Sign of Metabolic Syndrome: A Case-Control Study

  2014cited by this paper
• Relationship between skin tags, leptin hormone and metabolic disturbances

  2013cited by this paper
• Framingham Risk Score for Prediction of Cardiovascular Diseases: A Population-Based Study from Southern Europe

  2013cited by this paper
• The framingham risk score, diet, and inflammatory markers in Korean men with metabolic syndrome

  2012cited by this paper
• Skin tags, leptin, metabolic syndrome and change of the life style.

  2011cited by this paper
• [Association between skin tags and insulin resistance].

  2010cited by this paper
• Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus.

  2005cited by this paper
• Skin Tags and Atherosclerotic Risk Factors

  2005cited by this paper
• Rook's Textbook of Dermatology

  2004cited by this paper
• Prediction of coronary heart disease using risk factor categories.

  1998cited by this paper

• No citing papers are available for this paper.