Identification of residues contributing to the ATP binding site of Kir6.2

No abstract is available for this paper.

• Publication year

  2003

• Venue

  EMBO Journal

• Publication date

  2003-06-16

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/emboj/cdg282PMID 12805206PMCID PMC162134
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Physiological and pathophysiological roles of ATP-sensitive K+ channels.

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• Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2

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• The I182 region of k(ir)6.2 is closely associated with ligand binding in K(ATP) channel inhibition by ATP.

  2000cited by this paper
• Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide.

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• ATP4- mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites.

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