Xantivin suppresses the activity of EGF-CFC genes to regulate nodal signaling.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  International Journal of Developmental Biology

• Publication date

  2004-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1387/IJDB.041805KTPMID 15300508
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2002influential reference
• Multiple nodal-related genes act coordinately in Xenopus embryogenesis.

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• Morpholino oligos: making sense of antisense?

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• Lefty antagonism of Squint is essential for normal gastrulation.

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• TGF-β signalling pathways in early Xenopus development

  2001influential reference
• Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms.

  2001cited by this paper
• TGF-beta signalling pathways in early Xenopus development.

  2001influential reference
• Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo.

  2001cited by this paper
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• The lefty-related factor Xatv acts as a feedback inhibitor of nodal signaling in mesoderm induction and L-R axis development in xenopus.

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  1999cited by this paper
• Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways.

  1999cited by this paper
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• Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation.

  1999influential reference
• Regulation of midline development by antagonism of lefty and nodal signaling.

  1999cited by this paper
• Anterior Endomesoderm Specification in Xenopusby Wnt/-catenin and TGF- Signalling Pathways

  1999cited by this paper
• derrière: a TGF-beta family member required for posterior development in Xenopus.

  1999cited by this paper
• Antivin, a novel and divergent member of the TGFbeta superfamily, negatively regulates mesoderm induction.

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• Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis.

  1999cited by this paper
• Zebrafish organizer development and germ-layer formation require nodal-related signals

  1998cited by this paper
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  1998cited by this paper
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  1998influential reference
• Regulation of the Xmyf-5 and XmyoD Expression Pattern during Early Xenopus Development

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• Cripto is required for correct orientation of the anterior–posterior axis in the mouse embryo

  1998influential reference
• lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal.

  1998cited by this paper
• Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer.

  1997influential reference
• Two closely‐related left‐right asymmetrically expressed genes, lefty‐1 and lefty‐2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos

  1997cited by this paper
• Functional differences among Xenopus nodal-related genes in left-right axis determination.

  1997cited by this paper
• Left–right asymmetric expression of the TGFβ-family member lefty in mouse embryos

  1996cited by this paper
• The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development.

  1995influential reference
• Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation.

  1995influential reference
• Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes.

  1994cited by this paper
• A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse.

  1994influential reference
• The structure and expression of the Xenopus Krox-20 gene: conserved and divergent patterns of expression in rhombomeres and neural crest.

  1993cited by this paper
• Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene.

  1993cited by this paper
• Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation

  1993cited by this paper
• Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation.

  1993cited by this paper
• A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

  1992cited by this paper
• Ventral ectoderm of Xenopus forms neural tissue, including hindbrain, in response to activin.

  1992cited by this paper
• In situ hybridization: an improved whole-mount method for Xenopus embryos.

  1991cited by this paper
• Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction.

  1991cited by this paper
• Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis.

  1991cited by this paper
• Mesodermal induction in early amphibian embryos by activin A (erythroid differentiation factor)

  1990cited by this paper
• A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta.

  1987influential reference
• Normal Table of Xenopus Laevis (Daudin)

  1958cited by this paper

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• TGF-β Family Signaling in Early Vertebrate Development.

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• Agonists and Antagonists of TGF-β Family Ligands.

  2016cites this paper
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  2012cites this paper
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  2012cites this paper
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  2010cites this paper
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  2009cites this paper
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  2008cites this paper
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  2008cites this paper
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  2007cites this paper
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  2007cites this paper
• Molecular basis of vertebrate endoderm development.

  2007cites this paper
• Xenopus glucose transporter 1 (xGLUT1) is required for gastrulation movement in Xenopus laevis.

  2007cites this paper
• High-resolution studies of Xnr1 signaling and left-right asymmetry in Xenopus

  2007cites this paper
• The effect of post-translational modifications on Xlefty function.

  2007cites this paper
• Emergence of organizer function: a lot of "stuff" involved.

  2006cites this paper
• Nodal‐related gene Xnr5 is amplified in the Xenopus genome

  2006cites this paper
• In Vitro organogenesis using amphibian pluripotent cells

  2006cites this paper
• Maternal XTcf1 and XTcf4 have distinct roles in regulating Wnt target genes.

  2006cites this paper
• Cooperative non-cell and cell autonomous regulation of Nodal gene expression and signaling by Lefty/Antivin and Brachyury in Xenopus.

  2006cites this paper
• Monomeric mature protein of Nodal-related 3 activates Xbra expression

  2006cites this paper
• A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos.

  2006cites this paper
• Two distinct domains in pro-region of Nodal-related 3 are essential for BMP inhibition.

  2006cites this paper
• Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis

  2005cites this paper
• XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning

  2005cites this paper
• Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos.

  2005influential citation
• Cripto-1: an oncofetal gene with many faces.

  2005cites this paper