Chemically modified tetracyclines inhibit inducible nitric oxide synthase expression and nitric oxide production in cultured rat mesangial cells.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  1996-12-04

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1006/BBRC.1996.1787PMID 8954113
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nitric oxide stimulates the activity of a 72-kDa neutral matrix metalloproteinase in cultured rat mesangial cells.

  1996cited by this paper
• Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury.

  1996cited by this paper
• Interleukin-13 inhibits inducible nitric oxide synthase expression in human mesangial cells.

  1996cited by this paper
• Nitric oxide mediates immunologic injury to kidney mesangium in experimental glomerulonephritis.

  1995cited by this paper
• Nitric oxide activates metalloprotease enzymes in articular cartilage.

  1995cited by this paper
• Autocrine inhibition of Na+/K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells.

  1995cited by this paper
• Cytokines activate inducible nitric oxide synthase gene transcription in inner medullary collecting duct cells.

  1995cited by this paper
• Nitric oxide modulates the synthesis of extracellular matrix proteins in cultured rat mesangial cells.

  1995cited by this paper
• Nitric oxide synthases: roles, tolls, and controls.

  1994cited by this paper
• Regulation of biosynthesis of nitric oxide.

  1994cited by this paper
• Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene.

  1994cited by this paper
• Differential expression and induction of mRNAs encoding two inducible nitric oxide synthases in rat kidney.

  1994cited by this paper
• Cytokines and L-arginine in renal injury and repair.

  1994cited by this paper
• Redox signaling: nitrosylation and related target interactions of nitric oxide.

  1994cited by this paper
• The L-arginine-nitric oxide pathway.

  1993cited by this paper
• Evidence for the role of nitric oxide in macula densa control of glomerular hemodynamics.

  1993cited by this paper
• Adaptation to increased dietary salt intake in the rat. Role of endogenous nitric oxide.

  1993cited by this paper
• Cytokine-induced expression of a nitric oxide synthase in rat renal tubule cells.

  1993cited by this paper
• Endothelium-derived relaxing factor, nitric oxide: effects on and production by mesangial cells and the glomerulus.

  1993cited by this paper
• Importance of NO/EDRF for glomerular and tubular function: studies in the isolated perfused rat kidney.

  1992cited by this paper
• Proteolytic enzymes as mediators of glomerular injury.

  1991cited by this paper
• Nitric oxide. A novel signal transduction mechanism for transcellular communication.

  1990cited by this paper
• Inhibition of rat mesangial cell mitogenesis by nitric oxide-generating vasodilators.

  1989cited by this paper
• A Non-antibacterial Chemically-modified Tetracycline Inhibits Mammalian Collagenase Activity

  1987cited by this paper

• Rombus-shaped α-Fe₂O₃ nanoparticles for antibacterial and anticancer applications.

  2025cites this paper
• In Vitro Study of the Effects of Five Chemically Modified Tetracycline (CMT) Analogs on Human Epidermal Melanogenesis: Potential as Novel Anti-Melanogenic Agents

  2023cites this paper
• Tetracyclines—An Important Therapeutic Tool for Dermatologists

  2022cites this paper
• Chemically-Modified Curcumin 2.24: A Novel Systemic Therapy for Natural Periodontitis in Dogs

  2020cites this paper
• Immunomodulatory tetracyclines: Facing the complexity of intestinal inflammation

  2017cites this paper
• Chemically modified tetracyclines: The novel host modulating agents

  2015cites this paper
• COX-2-Mediated Prostaglandin E2 Modified Tetracyclines: Inhibition of A Novel Mechanism of Action of Chemically

  2013cites this paper
• Non-Antibacterial Implications of Tetracyclines in the Management of Periodontitis: An Update

  2013cites this paper
• Chemically modified tetracyclines: Novel therapeutic agents in the management of chronic periodontitis

  2012cites this paper
• Tetracycline-incorporated Silk Fibroin Films

  2012cites this paper
• Clinical applications of non-antimicrobial tetracyclines in dermatology.

  2011cites this paper
• Tetracyclines Inhibit Rat Osteoclast Formation and Activity In Vitro and Affect Bone Turnover in Young Rats In Vivo

  2010cites this paper
• Kinetics of inhibition of purified bovine neutrophil matrix metalloproteinase 9 by low-molecular-weight inhibitors.

  2009cites this paper
• The Antibiotic and Nonantibiotic Tetracyclines

  2007cites this paper
• Chemically modified tetracyclines inhibit VEGF secretion by breast cancer cell lines.

  2006cites this paper
• Nonantimicrobial effects of antibacterial agents.

  2005cites this paper
• Wolowacz not in Mesenchymal Cells Tetracycline Derivatives Induce Apoptosis Selectively in Cultured Monocytes and Macrophages but

  2005cites this paper
• Diabetes Y Altered host metabolism A Sub-gingival y Gram-negative microorganisms t Endotoxin Gingival collagenase i

  2005cites this paper
• CHEMICALLY MODIFIED TETRACYCLINE PREVENTS THE DEVELOPMENT OF SEPTIC SHOCK AND ACUTE RESPIRATORY DISTRESS SYNDROME IN A CLINICALLY APPLICABLE PORCINE MODEL

  2005cites this paper
• Effect of chemically modified tetracycline on transforming growth factor-β1 and caspase-3 activation in liver of septic rats*

  2005cites this paper
• Use of Tetracyclines for Bone Metastases

  2005cites this paper
• Chemically modified tetracyclines as inhibitors of matrix metalloproteinases.

  2004cites this paper
• Inhibition of Matrix Metalloproteinases by Chemically Modified Tetracyclines in Sepsis

  2003cites this paper
• Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability.

  2003cites this paper
• Nitric oxide and its role during pregnancy: from ovulation to delivery.

  2003cites this paper
• A nonantibiotic chemically modified tetracycline (CMT-3) inhibits intimal thickening.

  2003cites this paper
• Whole-body X-irradiation induces acute and transient expression of heme oxygenase-1 in rat liver.

  2002cites this paper
• Nitric oxide, inducible nitric oxide synthase and inflammation in veterinary medicine

  2002cites this paper
• Doxycycline modulates smooth muscle cell growth, migration, and matrix remodeling after arterial injury.

  2002cites this paper
• Matrix Metalloproteinase Inhibitors: Do They Have a Place in Anticancer Therapy?

  2002cites this paper
• Antiangiogenic Action of Chemically Modified Tetracyclines in Breast Cancer

  2002cites this paper
• Tetracyclines inhibit nitrosothiol production by cytokine-stimulated osteoarthritic synovial cells

  2001cites this paper
• Tetracyclines in Biology, Chemistry and Medicine

  2001cites this paper
• Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer.

  2001cites this paper
• Phase I C linical T rial o f O ral C OL-3, a M atrix Metalloproteinas e I nhibitor, i n P atients W ith R efractory Metastatic C ancer

  2001cites this paper
• Regulation of inflammatory mediators by tetracyclines

  2001cites this paper
• Inhibition of matrix metalloproteinases (MMPs) by tetracyclines

  2001cites this paper
• Biological, non-antibiotic properties of semi-synthetic and chemically modified tetracyclines — a structured, annotated bibliography

  2001cites this paper
• A role for the anti-inflammatory properties of tetracyclines in the prevention of acute lung injury.

  2001cites this paper
• General aspects of anti-angiogenesis and cancer therapy

  2001cites this paper
• Novel pharmacological agents in clinical development for solid tumours

  2001cites this paper
• Non-antimicrobial properties of tetracyclines--dental and medical implications.

  2001cites this paper
• Nitric oxide and tissue destruction.

  2001cites this paper
• Pathophysiological Roles of Nitric Oxide in Inflammation

  2000cites this paper
• Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis.

  2000cites this paper
• Nitric oxide production of rat Leydig and Sertoli cells is stimulated by round spermatid factor(s).

  2000cites this paper
• Morphine stimulates mesangial cell TNF-alpha and nitrite production.

  2000cites this paper
• Tetracyclines induce apoptosis in osteoclasts.

  2000cites this paper
• The Effects and Mechanism of Action of Cimetidine on Inducible Nitric Oxide Synthase Using an Equine Soft-Tissue Inflammation Model.

  2000cites this paper
• Morphine Stimulates Mesangial Cell TNF-α and Nitrite Production

  2000cites this paper
• Production 2 COX-2-Mediated Prostaglandin E Modified Tetracyclines : Inhibition of A Novel Mechanism of Action of Chemically and

  1999cites this paper
• A novel mechanism of action of chemically modified tetracyclines: inhibition of COX-2-mediated prostaglandin E2 production.

  1999cites this paper
• MMP‐Mediated Events in Diabetes

  1999cites this paper
• Review of Three New Agents That Target Angiogenesis, Matrix Metalloproteinases, and Cyclin-Dependent Kinases.

  1999cites this paper
• A Chemically Modified Nonantimicrobial Tetracycline (CMT‐8) Inhibits Gingival Matrix Metalloproteinases, Periodontal Breakdown, and Extra‐Oral Bone Loss in Ovariectomized Rats

  1999cites this paper
• Chemically modified non-antimicrobial tetracyclines inhibit activity of phospholipases A2.

  1998cites this paper
• Tetracycline Derivatives Induce Apoptosis Selectively in Cultured Monocytes and Macrophages but not in Mesenchymal Cells

  1998cites this paper
• Effects of Tetracyclines on the Pathologic Activity of Endotoxin: in Vitro and in Vivo Studies

  1998cites this paper
• Tetracycline-Based MMP Inhibitors Can Prevent Fibroblast-Mediated Collagen Gel Contraction In Vitro

  1998influential citation
• Effects of Chemically Modified Tetracyclines on iNOS in Mesangial Cells: Impact on Experimental Glomerulonephritis

  1998cites this paper
• Morphine enhances macrophage apoptosis.

  1998cites this paper
• Tetracyclines Inhibit Connective Tissue Breakdown by Multiple Non-Antimicrobial Mechanisms

  1998cites this paper
• Tetracycline prevents cancellous bone loss and maintains near-normal rates of bone formation in streptozotocin diabetic rats.

  1997cites this paper