Epalrestat, an Aldose Reductase Inhibitor, Improves an Impaired Generation of Oxygen-Derived Free Radicals by Neutrophils From Poorly Controlled NIDDM Patients

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Diabetes Care

• Publication date

  1997-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.2337/diacare.20.6.995PMID 9167113
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1993cited by this paper
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  1993influential reference
• Effects of Ponalrestat, an Aldose Reductase Inhibitor, on Neutrophil Killing of Escherichia Coli and Autonomic Function in Patients With Diabetes Mellitus

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  1992cited by this paper
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  1987cited by this paper
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  1984cited by this paper
• Chemiluminescence and superoxide anion production by leukocytes from diabetic patients.

  1983cited by this paper
• Mechanism of the luminol-dependent chemiluminescence of human neutrophils.

  1982cited by this paper
• Infection and diabetes mellitus.

  1979cited by this paper
• Oxygen-dependent microbial killing by phagocytes (first of two parts).

  1978cited by this paper
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  1978cited by this paper

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  2004cites this paper
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