Identification of absorbed components and metabolites of Zhi-Zi-Hou-Po decoction in rat plasma after oral administration by an untargeted metabolomics-driven strategy based on LC-MS

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Analytical and Bioanalytical Chemistry

• Publication date

  2016-06-24

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/s00216-016-9674-xPMID 27342796
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• geoRge: A Computational Tool To Detect the Presence of Stable Isotope Labeling in LC/MS-Based Untargeted Metabolomics.

  2016cited by this paper
• Comparative pharmacokinetics and brain distribution of magnolol and honokiol after oral administration of Magnolia officinalis cortex extract and its compatibility with other herbal medicines in Zhi-Zi-Hou-Po Decoction to rats.

  2016cited by this paper
• LC-MS-Based Metabolomics Discovers Purine Endogenous Associations with Low-Dose Salbutamol in Urine Collected for Antidoping Tests.

  2016cited by this paper
• Metabolome searcher: a high throughput tool for metabolite identification and metabolic pathway mapping directly from mass spectrometry and using genome restriction

  2015cited by this paper
• Identification of the absorbed components and metabolites of Zhi-Zi-Da-Huang decoction in rat plasma by ultra-high performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry.

  2015cited by this paper
• An untargeted metabolomics-driven approach based on LC-TOF/MS and LC-MS/MS for the screening of xenobiotics and metabolites of Zhi-Zi-Da-Huang decoction in rat plasma.

  2015cited by this paper
• Secondary metabolite perturbations in Phaseolus vulgaris leaves due to gamma radiation.

  2015cited by this paper
• UPLC-ESI-TOF MS-Based Metabolite Profiling of the Antioxidative Food Supplement Garcinia buchananii.

  2015cited by this paper
• PLS/OPLS models in metabolomics: the impact of permutation of dataset rows on the K-fold cross-validation quality parameters.

  2015cited by this paper
• Metabolite identification for mass spectrometry-based metabolomics using multiple types of correlated ion information.

  2015cited by this paper
• Metabolite Profiling of Soybean Seed Extracts from Near-Isogenic Low and Normal Phytate Lines Using Orthogonal Separation Strategies.

  2015cited by this paper
• An effective integrated method for comprehensive identification of eighty-five compounds in Zhi-Zi-Da-Huang decoction by HPLC-DAD-ESI-MS (TOF) and HPLC-DAD-ESI-MS/MS (QqQ) without the help of reference standards

  2014cited by this paper
• Comparative evaluation of eight software programs for alignment of gas chromatography-mass spectrometry chromatograms in metabolomics experiments.

  2014cited by this paper
• Identification and distribution of four metabolites of geniposide in rats with adjuvant arthritis.

  2014cited by this paper
• Comparative evaluation of preprocessing freeware on chromatography/mass spectrometry data for signature discovery.

  2014cited by this paper
• Metabolism of Genipin in Rat and Identification of Metabolites by Using Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Tandem Mass Spectrometry

  2013cited by this paper
• Identification of honokiol metabolites in rats by the method of stable isotope cluster technique and ultra-high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry.

  2013cited by this paper
• Rapid discovery and global characterization of chemical constituents and rats metabolites of Phellodendri amurensis cortex by ultra-performance liquid chromatography-electrospray ionization/quadrupole-time-of-flight mass spectrometry coupled with pattern recognition approach.

  2013cited by this paper
• Effect of aqueous extract and fractions of Zhi-Zi-Hou-Pu decoction against depression in inescapable stressed mice: Restoration of monoamine neurotransmitters in discrete brain regions

  2013cited by this paper
• Confirmation of diosmetin 3-O-glucuronide as major metabolite of diosmin in humans, using micro-liquid-chromatography–mass spectrometry and ion mobility mass spectrometry

  2013cited by this paper
• Pharmacokinetics of Geniposide in Zhi‐Zi‐Hou‐Pu Decoction and in Different Combinations of its Constituent Herbs

  2012cited by this paper
• Effect of different formula compatibility of Zhizi Houpu decoction on the pharmacokinetics of naringenin and hesperetin

  2011cited by this paper
• In vitro metabolism and disposition of honokiol in rat and human livers.

  2011cited by this paper
• LC Characterization of the Major Constituents in Zhi-Zi-Hou-Pu Decoction Using Various Detection Approaches

  2009cited by this paper
• Mangiferin and hesperidin metabolites are absorbed from the gastrointestinal tract of pigs after oral ingestion of a Cyclopia genistoides (honeybush tea) extract.

  2008cited by this paper
• Structure elucidation of phase II metabolites by tandem mass spectrometry: an overview.

  2005cited by this paper
• Metabolites of orally administered Magnolia officinalis extract in rats and man and its antidepressant‐like effects in mice

  2003cited by this paper

• Characterization of Chemical Constituents and Metabolites in Rat Plasma after Oral Administration of Zhi-Zi-Hou-Po Decoction by High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry.

  2025cites this paper
• Integrated UHPLC-Q-TOF-MS Technology and Network Pharmacology Exploring the Pharmacodynamic Material Basis and Mechanism of Zhi-Zi-Hou-Po Granule for Treatment of Depression-Anxiety Comorbidity.

  2025cites this paper
• Qualitative and quantitative studies on chemical constituents of Ling-gui-zhu-gan decoction: In vitro and in vivo.

  2023cites this paper
• Computational method for rapid screening of the metabolites of Pulsatilla chinensis in rats using UHPLC-Q-TOF/MS combined with mass spectrum-based orthogonal projection.

  2023cites this paper
• Global xenobiotic profiling of rat plasma using untargeted metabolomics and background subtraction-based approaches: Method evaluation and comparison.

  2023cites this paper
• Discovery of the toxicity-related quality markers and mechanisms of zhi-zi-hou-Po decoction based on chinmedomics combined with differential absorbed components and network pharmacology.

  2023cites this paper
• Recent Progress on Mass Spectrum Based Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Traditional Chinese Medicine.

  2022cites this paper
• Comparative Pharmacokinetic Study of Three Major Bioactive Components in the Normal and Different Courses of Liver-Stagnation and Spleen-Deficiency Syndrome Depressive Rats after Intragastric Administration of Zhi-Zi-Hou-Po Decoction

  2022cites this paper
• Classification-based strategies to simplify complex traditional Chinese medicine (TCM) researches through liquid chromatography-mass spectrometry in the last decade (2011-2020): Theory, technical route and difficulty.

  2021cites this paper
• Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Zhi-Zi-Hou-Po Decoction in Depression

  2021cites this paper
• Identifying the effectual-combination ingredients of Zhi-zi-Hou-po decoction based on metabolic difference-oriented network regulation strategy.

  2021cites this paper
• Construction and Chemical Profile on “Activity Fingerprint” of Citri Reticulatae Pericarpium from Different Cultivars Based on HPLC-UV, LC/MS-IT-TOF, and Principal Component Analysis

  2020cites this paper
• Metabolic profile analysis of Zhi-zi-chi decoction in feces of normal and chronic unpredictable mild stress-induced depression rats based on UHPLC-ESI-Q-TOF-MS/MS and multiple analytical strategies

  2019cites this paper
• Comprehensive metabolic profile of phenolic acids and flavonoids in Glechomae Herba using ultra‐high‐performance liquid chromatography coupled to quadrupole‐time‐of‐flight tandem mass spectrometry with diagnostic ion filtering strategy

  2019cites this paper
• Evaluation of the Hepatotoxicity of the Zhi-Zi-Hou-Po Decoction by Combining UPLC-Q-Exactive-MS-Based Metabolomics and HPLC-MS/MS-Based Geniposide Tissue Distribution

  2019cites this paper
• Identification and analysis of components in Shen‐Fu‐Shu granule extract and in rat plasma after oral administration by UPLC‐ESI/Q‐TOF‐MS

  2019cites this paper
• Simultaneous determination of eight bioactive constituents of Zhi-Zi-Hou-Po Decoction in rat plasma by ultra-high performance liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study.

  2019cites this paper
• The Effects of Different Varieties of Aurantii Fructus Immaturus on the Potential Toxicity of Zhi-Zi-Hou-Po Decoction Based on Spectrum-Toxicity Correlation Analysis

  2019cites this paper
• Rapid identification of absorbed components and metabolites of Gandou decoction in rat plasma and liver by UPLC-Q-TOF-MSE.

  2019cites this paper
• Isoflavones' effects on pharmacokinetic profiles of main iridoids from Gardeniae Fructus in rats

  2019cites this paper
• Plasma metabolic profiling analysis of normal and ANIT-induced cholestasis rats after oral administration of Da-Huang-Xiao-Shi decoction using UHPLC-Q-Orbitrap MS coupled with pattern recognition

  2018cites this paper
• Investigation on pharmacochemistry and pharmacokinetics of atractylenolides from Atractylodes in vivo based on UPLC-MS combined with everted gut sac model in vitro

  2018influential citation
• Characterization of global metabolic profile of Zhi-Zi-Hou-Po decoction in rat bile, urine and feces after oral administration based on a strategy combining LC-MS and chemometrics.

  2017cites this paper
• Rapid discovery and identification of the prototypes and their metabolites of Da-Huang-Xiao-Shi decoction in rat plasma by an integrative strategy based on liquid chromatography coupled with mass spectrometry.

  2017cites this paper