Artesunate inhibits proliferation of naïve CD4+ T cells but enhances function of effector T cells

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Archives of pharmacal research

• Publication date

  2014-11-06

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1007/s12272-014-0491-5
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999influential reference
• CD69, CD25, and HLA-DR activation antigen expression on CD3+ lymphocytes and relationship to serum TNF-alpha, IFN-gamma, and sIL-2R levels in aging.

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  1998influential reference
• Biology of the interleukin-2 receptor.

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  1996influential reference
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