Particles suspended in the air we breathe are deposited in the airways as a function of the properties of the particle itself (shape, size and hydration), inspiratory air flow, airway anatomy, breathing environment, and mucociliary clearance. The scientific study of the deposition of inhaled particles in the airways has been conducted using traditional mathematical models and imaging techniques with particle markers. In recent years, the integration of statistical and computer methods, giving rise to a new discipline called digital microfluidics, has led to significant advances. In routine clinical practice, these studies are of great use for optimizing inhaler devices in line with particular characteristics of the drug to be inhaled and the pathology of the patient.
Deposition and Clinical Impact of Inhaled Particles in the Lung.
P. Clara,F. R. Jerez,J. Ramírez,C. M. González
Published 2023 in Archivos de Bronconeumologia
ABSTRACT
PUBLICATION RECORD
- Publication year
2023
- Venue
Archivos de Bronconeumologia
- Publication date
2023-02-01
- Fields of study
Medicine, Environmental Science
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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