Lymphocytes in peripheral blood as differential indicator of the stage of pathological condition in urooncological patients

P. Yakovlev,D. Klyushin

Published 2017 in Likarska sprava

ABSTRACT

Absolute lymphocyte count and neutrophil/lymphocyte ratio are the indicators of systemic inflammatory response involved in pathogenesis and progression of cancer. We demonstrate that absolute lymphocyte count and share of lymphocytes in peripheral blood truly differentiate between different states of the disease: urological cancer, healthy individual, benign urological condition and urological cancer after radical treatment. Considering involvement of lymphocytes in systemic inflammatory response and pathogenesis of cancer medical interventions targeting lymphocyte may yield therapeutic benefits.

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