Staying hydrated in sea water.

Reduction of intestinal lumen osmotic pressure by formation of Ca(Mg)CO3, "ichthyocarbonate", is essential for osmoregulation by the only vertebrate group, ray-finned fishes, widely capable of hydrating by ingesting seawater. Ichthyocarbonate formation and excretion is under elaborate physiological control and plays an important, yet still poorly defined, role in the oceanic carbon cycle.

• Publication year

  2023

• Venue

  Physiology

• Publication date

  2023-03-14

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1152/physiol.00005.2023PMID 36917964
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Receptor Guanylyl Cyclase C and Cyclic GMP in Health and Disease: Perspectives and Therapeutic Opportunities

  2022cited by this paper
• Magnesium transport in the aglomerular kidney of the Gulf toadfish (Opsanus beta)

  2021cited by this paper
• Estimating global biomass and biogeochemical cycling of marine fish with and without fishing

  2021cited by this paper
• Osmotrophy of dissolved organic carbon by coccolithophores in darkness

  2021cited by this paper
• Metrics that matter for assessing the ocean biological carbon pump

  2020cited by this paper
• Let more big fish sink: Fisheries prevent blue carbon sequestration—half in unprofitable areas

  2020cited by this paper
• Increased intestinal carbonate precipitate abundance in the sea bream (Sparus aurata L.) in response to ocean acidification

  2019cited by this paper
• The oceanic sink for anthropogenic CO2 from 1994 to 2007

  2019cited by this paper
• Regulation of Bicarbonate Secretion in Marine Fish Intestine by the Calcium-Sensing Receptor

  2018cited by this paper
• Renoguanylin stimulates apical CFTR translocation and decreases HCO3− secretion through PKA activity in the Gulf toadfish (Opsanus beta)

  2018cited by this paper
• Comparison of the organic matrix found in intestinal CaCO3 precipitates produced by several marine teleost species.

  2018cited by this paper
• Interrogation of the Gulf toadfish intestinal proteome response to hypersalinity exposure provides insights into osmoregulatory mechanisms and regulation of carbonate mineral precipitation.

  2018cited by this paper
• Phase heterogeneity in carbonate production by marine fish influences their roles in sediment generation and the inorganic carbon cycle

  2017cited by this paper
• Fractionation of the Gulf toadfish intestinal precipitate organic matrix reveals potential functions of individual proteins.

  2017cited by this paper
• Elevated CO2 increases energetic cost and ion movement in the marine fish intestine

  2016cited by this paper
• The role of the rectum in osmoregulation and the potential effect of renoguanylin on SLC26a6 transport activity in the Gulf toadfish (Opsanus beta).

  2016cited by this paper
• Microbial and diagenetic steps leading to the mineralisation of Great Salt Lake microbialites

  2016cited by this paper
• A proteinaceous organic matrix regulates carbonate mineral production in the marine teleost intestine

  2016cited by this paper
• Changes to Intestinal Transport Physiology and Carbonate Production at Various CO2 Levels in a Marine Teleost, the Gulf Toadfish (Opsanus beta)

  2016cited by this paper
• The differential role of renoguanylin in osmoregulation and apical Cl-/HCO3- exchange activity in the posterior intestine of the Gulf toadfish (Opsanus beta).

  2015cited by this paper
• Esophageal desalination is mediated by Na⁺, H⁺ exchanger-2 in the gulf toadfish (Opsanus beta).

  2014cited by this paper
• Large mesopelagic fishes biomass and trophic efficiency in the open ocean

  2014cited by this paper
• Osmoregulation and excretion.

  2014cited by this paper
• Osmoregulatory bicarbonate secretion exploits H+-sensitive haemoglobins to autoregulate intestinal O2 delivery in euryhaline teleosts

  2014cited by this paper
• Guanylin peptides regulate electrolyte and fluid transport in the Gulf toadfish (Opsanus beta) posterior intestine.

  2014cited by this paper
• Biogenic Fish-gut Calcium Carbonate is a Stable Amorphous Phase in the Gilt-head Seabream, Sparus aurata

  2013cited by this paper
• Why are there so few fish in the sea?

  2012cited by this paper
• Ocean Acidification Leads to Counterproductive Intestinal Base Loss in the Gulf Toadfish (Opsanus beta)

  2012cited by this paper
• Euryhaline pufferfish NBCe1 differs from nonmarine species NBCe1 physiology.

  2012cited by this paper
• Water absorption and bicarbonate secretion in the intestine of the sea bream are regulated by transmembrane and soluble adenylyl cyclase stimulation

  2012cited by this paper
• Independence of net water flux from paracellular permeability in the intestine of Fundulus heteroclitus, a euryhaline teleost

  2012cited by this paper
• Compensatory regulation of acid–base balance during salinity transfer in rainbow trout (Oncorhynchus mykiss)

  2011cited by this paper
• Unshelled abalone and corrupted urchins: development of marine calcifiers in a changing ocean

  2011cited by this paper
• Fish as major carbonate mud producers and missing components of the tropical carbonate factory

  2011cited by this paper
• Concentration of MgSO4 in the intestinal lumen of Opsanus beta limits osmoregulation in response to acute hypersalinity stress.

  2011cited by this paper
• Regulation of apical H⁺-ATPase activity and intestinal HCO₃⁻ secretion in marine fish osmoregulation.

  2011cited by this paper
• Cytosolic carbonic anhydrase in the Gulf toadfish is important for tolerance to hypersalinity.

  2010cited by this paper
• Modulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclase.

  2010cited by this paper
• Basolateral NBCe1 plays a rate-limiting role in transepithelial intestinal HCO3– secretion, contributing to marine fish osmoregulation

  2010cited by this paper
• The involvement of SLC26 anion transporters in chloride uptake in zebrafish (Danio rerio) larvae

  2009cited by this paper
• The involvement of H+-ATPase and carbonic anhydrase in intestinal HCO3– secretion in seawater-acclimated rainbow trout

  2009cited by this paper
• High rates of HCO3– secretion and Cl– absorption against adverse gradients in the marine teleost intestine: the involvement of an electrogenic anion exchanger and H+-pump metabolon?

  2009cited by this paper
• Contribution of Fish to the Marine Inorganic Carbon Cycle

  2009cited by this paper
• Effects of salinity on intestinal bicarbonate secretion and compensatory regulation of acid–base balance in Opsanus beta

  2008cited by this paper
• Assessing the Contribution of Foraminiferan Protists to Global Ocean Carbonate Production 1

  2008cited by this paper
• Ocean Acidification and Its Potential Effects on Marine Ecosystems

  2008cited by this paper
• Identification of intestinal bicarbonate transporters involved in formation of carbonate precipitates to stimulate water absorption in marine teleost fish

  2008cited by this paper
• Intestinal carbonic anhydrase, bicarbonate, and proton carriers play a role in the acclimation of rainbow trout to seawater.

  2007cited by this paper
• Intestinal anion exchange in teleost water balance.

  2007cited by this paper
• The intestinal guanylin system and seawater adaptation in eels.

  2007cited by this paper
• Calcium carbonate formation and dissolution.

  2007cited by this paper
• Maintaining osmotic balance with an aglomerular kidney.

  2006cited by this paper
• Evolutionary aspects of intestinal bicarbonate secretion in fish.

  2006cited by this paper
• Intestinal anion exchange in marine fish osmoregulation

  2006cited by this paper
• Ouabain-sensitive bicarbonate secretion and acid absorption by the marine teleost fish intestine play a role in osmoregulation.

  2006cited by this paper
• The multifunctional fish gill: dominant site of gas exchange, osmoregulation, acid-base regulation, and excretion of nitrogenous waste.

  2005cited by this paper
• Microbial lithification in marine stromatolites and hypersaline mats.

  2005cited by this paper
• Plasma and Urine Levels of Electrolytes, Urea and Steroid Hormones Involved in Osmoregulation of Cetaceans

  2005cited by this paper
• Bicarbonate secretion plays a role in chloride and water absorption of the European flounder intestine.

  2005cited by this paper
• Anthropogenic ocean acidification over the twenty-first century and its impact on calcifying organisms

  2005cited by this paper
• Kidneys sans glomeruli.

  2004cited by this paper
• Role of tubular secretion and carbonic anhydrase in vertebrate renal sulfate excretion.

  2004cited by this paper
• The Oceanic Sink for Anthropogenic CO2

  2004cited by this paper
• Active sulfate secretion by the intestine of winter flounder is through exchange for luminal chloride.

  2003cited by this paper
• Intestinal bicarbonate secretion in marine teleost fish-source of bicarbonate, pH sensitivity, and consequences for whole animal acid-base and calcium homeostasis.

  2003cited by this paper
• Urea based osmoregulation and endocrine control in elasmobranch fish with special reference to euryhalinity.

  2003cited by this paper
• Carbonate Mysteries

  2002cited by this paper
• NaCl and fluid secretion by the intestine of the teleost Fundulus heteroclitus: involvement of CFTR.

  2002cited by this paper
• Intestinal bicarbonate secretion by marine teleost fish--why and how?

  2002cited by this paper
• Osmoregulation in marine mammals.

  2001cited by this paper
• The global carbon cycle: a test of our knowledge of earth as a system.

  2000cited by this paper
• Intestinal base excretion in the seawater-adapted rainbow trout: a role in acid-base balance?

  1996cited by this paper
• Increased vascularity of the lingual salt glands of the estuarine crocodile, Crocodylus porosus, kept in hyperosmotic salinity

  1993cited by this paper
• Ion transport of marine teleost intestine.

  1990cited by this paper
• Esophageal desalination of seawater in flounder: role of active sodium transport.

  1983cited by this paper
• Na+ −K+ −Cl− co-transport in the intestine of a marine teleost

  1982cited by this paper
• Serum composition of the coelacanth, Latimeria chalumnae Smith.

  1974cited by this paper
• Electrolyte excretion by the salt gland of the Galápagos marine iguana.

  1969cited by this paper
• Ingestion, intestinal absorption, and elimination of seawater and salts in the southern flounder, Paralichthys lethostigma.

  1968cited by this paper
• Extrarenal salt excretion in sea snakes (Laticauda).

  1967cited by this paper
• The Salt Gland in a Sea Snake (Laticauda)

  1967cited by this paper
• Observations on the Solubility of Skeletal Carbonates in Aqueous Solutions

  1962cited by this paper
• The Salt‐Secreting Gland of Marine Birds

  1960cited by this paper

• Crude extract of cyanobacterium (Radiocystis fernandoi) triggers primary osmoregulatory impairment in the gills of nile tilapia (Oreochromis niloticus)

  2026cites this paper
• Sedimentological characterisation is a necessary prerequisite for interpretation of stable carbon isotope ratios of bulk sediment from reefal settings

  2025cites this paper
• Fish Carbonates in the North Atlantic and Their Potential Role in the Carbon Cycle

  2025cites this paper
• Osmoregulation by the gastro-intestinal tract of marine fish at depth – implications for the global carbon cycle

  2025cites this paper
• Molecular responses in the intestine of Atlantic salmon (Salmo salar) following light and diet stimulation of smoltification: Potential molecular markers for a seawater-ready smolt

  2024cites this paper
• Organic Coatings Reduce Dissolution Rate by an Order of Magnitude for Carbonate Minerals Produced by Marine Fish

  2024cites this paper
• Physiological responses of euryhaline marine fish to naturally-occurring hypersalinity.

  2024cites this paper
• Implications of dietary carbon incorporation in fish carbonates for the global carbon cycle.

  2024cites this paper
• The role of marine fish-produced carbonates in the oceanic carbon cycle is determined by size, specific gravity, and dissolution rate.

  2024cites this paper
• Control of fluid intake in dehydrated rats and evolution of sodium appetite.

  2024cites this paper
• Physiology in Perspective.

  2023cites this paper
• Evolving views of ionic, osmotic and acid-base regulation in aquatic animals.

  2023cites this paper