Celecoxib, but not indomethacin, ameliorates the hypertensive and perivascular fibrotic actions of cyclosporine in rats: role of endothelin signaling.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Toxicology and Applied Pharmacology

• Publication date

  2015-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.taap.2015.01.018PMID 25656942
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-β1/IL-2/COX-2/endothelin ET(B) receptor cascade.

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  2005cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• Immunosuppressant-Induced Nephropathy

  1999cited by this paper
• Bosentan ameliorates cyclosporin A-induced hypertension in rats and primates.

  1996influential reference
• VASCULAR ENDOTHELIN RESPONSIVENESS AND RECEPTOR CHARACTERISTICS IN VITRO AND EFFECTS OF ENDOTHELIN RECEPTOR BLOCKADE IN VIVO IN CYCLOSPORIN HYPERTENSION

  1994influential reference
• Interaction of cyclosporine A and nonsteroidal anti-inflammatory drugs on renal function in patients with rheumatoid arthritis.

  1992cited by this paper
• Carleton's Histological Technique

  1980cited by this paper

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  2024cites this paper
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  2023cites this paper
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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017influential citation
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  2017cites this paper
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  2016cites this paper
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  2015influential citation
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