A PROSPECTIVE STUDY ON ANTIMICROBIAL PROPHYLAXIS USE IN ORTHOPEDIC SURGICAL INPATIENTS AT A TERTIARY CARE HOSPITAL

Prabhat Lakkireddy,Ratnamani M S,D. Sanjana,Maryam Maqsood,Khazra Jameel,G. Raghu,Salluri Supraja

Published 2023 in International journal of scientific research

ABSTRACT

Introduction: Surgical Antimicrobial Prophylaxis plays a crucial role in prevention of Surgical Site Infections which are potentially preventable and are multifactorial in nature. Materials and Methods: Aprospective, observational, single centre study was conducted on 165 patients to study the administration of surgical antimicrobial prophylaxis and incidence of surgical site infections. Results: Most common surgeries were Knee Replacement, Hip replacement, Open Reduction Internal Fixations, and Closed Reduction and Manipulations. The most utilized drug irrespective of surgical procedure was found to be cefuroxime at 1.5 grams, both preoperatively and post operatively. Out of 165 patients, 9 patients showed signs of SSI (incidence rate:5.45%), while others had healthy wound recovery. Conclusion: The prevention of SSIs, while accounting for signicant risk factors, avoiding increased postoperative hospital stay and escalated expenses justies the adoption of the practice of antimicrobial prophylaxis and employment of a parameter-based detection and treatment.

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