Multi-directional function of the protein phosphatase 1 regulatory subunit TIMAP.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2013-06-14

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.bbrc.2013.05.012PMID 23685145
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins.

  2013cited by this paper
• The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ.

  2011influential reference
• Characterization of the effect of TIMAP phosphorylation on its interaction with protein phosphatase 1.

  2011cited by this paper
• The extended PP1 toolkit: designed to create specificity.

  2010cited by this paper
• TIMAP is a positive regulator of pulmonary endothelial barrier function.

  2008cited by this paper
• Extracellular ATP induces assembly and activation of the myosin light chain phosphatase complex in endothelial cells.

  2007influential reference
• Phosphorylation of TIMAP by Glycogen Synthase Kinase-3β Activates Its Associated Protein Phosphatase 1*

  2007cited by this paper
• Phosphorylation of Myosin Phosphatase Targeting Subunit 3 (MYPT3) and Regulation of Protein Phosphatase 1 by Protein Kinase A*

  2006influential reference
• The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

  2006cited by this paper
• The protein phosphatase-1 targeting subunit TIMAP regulates LAMR1 phosphorylation.

  2005cited by this paper
• Structural basis of protein phosphatase 1 regulation

  2004influential reference
• Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding.

  2004cited by this paper
• Crystal Structure and Mutagenesis of a Protein Phosphatase-1:Calcineurin Hybrid Elucidate the Role of the β12-β13 Loop in Inhibitor Binding*

  2004cited by this paper
• The essential role of PP1beta in Drosophila is to regulate nonmuscle myosin.

  2004cited by this paper
• mPPP1R16B is a novel mouse protein phosphatase 1 targeting subunit whose mRNA is located in cell bodies and dendrites of neurons in four distinct regions of the brain.

  2002cited by this paper
• TIMAP, a novel CAAX box protein regulated by TGF-beta1 and expressed in endothelial cells.

  2002cited by this paper
• Cloning and identification of MYPT3: a prenylatable myosin targetting subunit of protein phosphatase 1.

  2001influential reference
• The major myosin phosphatase in skeletal muscle is a complex between the β‐isoform of protein phosphatase 1 and the MYPT2 gene product

  1998cited by this paper
• Interaction of myosin phosphatase target subunit 1 with the catalytic subunit of type 1 protein phosphatase.

  1998cited by this paper
• Identification of the separate domains in the hepatic glycogen-targeting subunit of protein phosphatase 1 that interact with phosphorylase a, glycogen and protein phosphatase 1.

  1998cited by this paper
• A Molecular Basis for Different Interactions of Marine Toxins with Protein Phosphatase-1

  1997cited by this paper
• Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

  1997cited by this paper
• Interactions of the Subunits of Smooth Muscle Myosin Phosphatase*

  1997influential reference
• SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

  1997cited by this paper
• Phosphorylation of the Large Subunit of Myosin Phosphatase and Inhibition of Phosphatase Activity (*)

  1996cited by this paper
• Purification of type 1 protein (serine/threonine) phosphatases by microcystin‐Sepharose affinity chromatography

  1994influential reference
• Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.

  1994cited by this paper
• Expression of recombinant inhibitor-2 in E. coli and its utilization for the affinity chromatography of protein phosphatase-1.

  1994cited by this paper
• Functional domains of the 67-kDa laminin receptor precursor.

  1991cited by this paper
• Liquid chromatography-linked protein phosphatase bioassay; a highly sensitive marine bioscreen for okadaic acid and related diarrhetic shellfish toxins.

  1991cited by this paper
• Regulation of bovine glomerular endothelial cell growth in vitro.

  1989cited by this paper

• Hypoxia-induced TIMAP Upregulation in Endothelial Cells and TIMAP-dependent Tumour Angiogenesis.

  2024cites this paper
• Role of Protein Phosphatases in Tumor Angiogenesis: Assessing PP1, PP2A, PP2B and PTPs Activity

  2024cites this paper
• Serine/Threonine Protein Phosphatases 1 and 2A in Lung Endothelial Barrier Regulation

  2023cites this paper
• TIMAP, a Regulatory Subunit of Protein Phosphatase 1, Inhibits In Vitro Neuronal Differentiation

  2023cites this paper
• TIMAP Upregulation Correlates Negatively with Survival in HER2- Negative Subtypes of Breast Cancer

  2021cites this paper
• Heat Shock-Induced Dephosphorylation of Eukaryotic Elongation Factor 1BδL by Protein Phosphatase 1

  2021cites this paper
• TIMAP inhibits endothelial myosin light chain phosphatase by competing with MYPT1 for the catalytic protein phosphatase 1 subunit PP1cβ

  2019cites this paper
• Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis.

  2019cites this paper
• Investigation of Gene Splicing Variants Contributing Risk to Psychiatric Disorders

  2017influential citation
• TIMAP, the versatile protein phosphatase 1 regulator in endothelial cells

  2017influential citation
• TIMAP-protein phosphatase 1-complex controls endothelin-1 production via ECE-1 dephosphorylation.

  2016cites this paper
• TIMAP repression by TGFβ and HDAC3-associated Smad signaling regulates macrophage M2 phenotypic phagocytosis

  2016cites this paper
• Elongation factor-1A1 is a novel substrate of the protein phosphatase 1-TIMAP complex.

  2015cites this paper
• Protein phosphatase 1 catalytic isoforms: specificity toward interacting proteins.

  2014cites this paper
• TIMAP promotes angiogenesis by suppressing PTEN-mediated Akt inhibition in human glomerular endothelial cells.

  2014cites this paper