Epithelial galectin-3 induces mitochondrial complex inhibition and cell cycle arrest of CD8+ T Cells in severe/critical ill COVID-19

No abstract is available for this paper.

• Publication year

  2023

• Venue

  bioRxiv

• Publication date

  2023-03-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/2023.03.14.532609
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Characteristics of lymphocyte subset alterations in COVID-19 patients with different levels of disease severity

  2022cited by this paper
• Differential Susceptibility of Retinal Neurons to the Loss of Mitochondrial Biogenesis Factor Nrf1

  2022cited by this paper
• The Biological Functions and Clinical Significance of SARS-CoV-2 Variants of Corcern

  2022cited by this paper
• SARS-CoV-2 viroporin encoded by ORF3a triggers the NLRP3 inflammatory pathway

  2022cited by this paper
• Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients

  2021cited by this paper
• Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19

  2021cited by this paper
• Reduction and exhausted features of T lymphocytes under serological changes, and prognostic factors in COVID-19 progression

  2021cited by this paper
• Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

  2020cited by this paper
• The ORF3a protein of SARS-CoV-2 induces apoptosis in cells

  2020cited by this paper
• The Metabolic Changes and Immune Profiles in Patients With COVID-19

  2020cited by this paper
• Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

  2020cited by this paper
• Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

  2020cited by this paper
• The metabolic and immunological characteristics of pregnant women with COVID-19 and their neonates

  2020cited by this paper
• Immunopathology of galectin-3: an increasingly promising target in COVID-19.

  2020cited by this paper
• Functional exhaustion of antiviral lymphocytes in COVID-19 patients

  2020cited by this paper
• Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis

  2019cited by this paper
• Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

  2018cited by this paper
• Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity

  2018cited by this paper
• Mutual Antagonism of PINK1/Parkin and PGC-1α Contributes to Maintenance of Mitochondrial Homeostasis in Rotenone-Induced Neurotoxicity

  2018cited by this paper
• Cell cycle proliferation decisions: the impact of single cell analyses

  2017cited by this paper
• Fueling the Cell Division Cycle.

  2017cited by this paper
• Mitochondria: A master regulator in macrophage and T cell immunity.

  2017cited by this paper
• Mitochondrial activity in T cells.

  2017cited by this paper
• Reconstructing cell cycle pseudo time-series via single-cell transcriptome data

  2017cited by this paper
• Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.

  2015cited by this paper
• Cell cycle–dependent regulation of mitochondrial preprotein translocase

  2014cited by this paper
• Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

  2013cited by this paper
• Transcriptional control of mitochondrial biogenesis and function.

  2009cited by this paper
• Nuclear Control of Respiratory Chain Expression by Nuclear Respiratory Factors and PGC‐1‐Related Coactivator

  2008cited by this paper
• Galectins: matricellular glycan-binding proteins linking cell adhesion, migration, and survival

  2007cited by this paper

• Epithelial Galectin-3 Induced the Mitochondrial Complex Inhibition and Cell Cycle Arrest of CD8+ T Cells in Severe/Critical COVID-19

  2023cites this paper