Helicobacter pylori–specific Protection Against Inflammatory Bowel Disease Requires the NLRP3 Inflammasome and IL-18

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Inflammatory Bowel Diseases

• Publication date

  2015-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/MIB.0000000000000318PMID 25742401
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Genetic Polymorphisms in the IL-18 Gene and Ulcerative Colitis Risk: A Meta-Analysis

  2014cited by this paper
• Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10

  2014cited by this paper
• Helicobacter pylori–Induced IL-1β Secretion in Innate Immune Cells Is Regulated by the NLRP3 Inflammasome and Requires the Cag Pathogenicity Island

  2014cited by this paper
• NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion.

  2014cited by this paper
• Probiotics in the mechanism of protection against gut inflammation and therapy of gastrointestinal disorders.

  2014cited by this paper
• Helicobacter pylori γ-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance

  2013cited by this paper
• Top-Down or Step-Up Treatment in Crohn's Disease?

  2013cited by this paper
• Moving towards disease modification in inflammatory bowel disease therapy

  2013cited by this paper
• The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL‐1β production in Helicobacter pylori infected dendritic cells

  2013influential reference
• The Association Between Asthma and Helicobacter pylori: A Meta‐Analysis

  2013cited by this paper
• Controlling the frontier: regulatory T-cells and intestinal homeostasis.

  2013cited by this paper
• DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection.

  2012cited by this paper
• Heligmosomoides polygyrus bakeri Induces Tolerogenic Dendritic Cells that Block Colitis and Prevent Antigen-Specific Gut T Cell Responses

  2012cited by this paper
• Caspase-1 Has Both Proinflammatory and Regulatory Properties in Helicobacter Infections, Which Are Differentially Mediated by Its Substrates IL-1β and IL-18

  2012cited by this paper
• Low prevalence of Helicobacter pylori infection among patients with inflammatory bowel disease

  2012cited by this paper
• Helicobacter pylori DNA decreases pro-inflammatory cytokine production by dendritic cells and attenuates dextran sodium sulphate-induced colitis

  2011cited by this paper
• Inflammatory bowel disease.

  2011cited by this paper
• RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

  2011cited by this paper
• Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells.

  2011cited by this paper
• Prior Helicobacter pylori infection ameliorates Salmonella typhimurium‐induced colitis: Mucosal crosstalk between stomach and distal intestine

  2011cited by this paper
• Tolerance rather than immunity protects from Helicobacter pylori-induced gastric preneoplasia.

  2011cited by this paper
• Heligmosomoides polygyrus Infection Can Inhibit Colitis through Direct Interaction with Innate Immunity

  2010cited by this paper
• Association between Helicobacter pylori infection and inflammatory bowel disease: A meta‐analysis and systematic review of the literature†

  2010cited by this paper
• Inflammatory bowel disease.

  2009cited by this paper
• The CD4+ T Cell-Mediated IFN-γ Response to Helicobacter Infection Is Essential for Clearance and Determines Gastric Cancer Risk1

  2009cited by this paper
• The role of microbes in Crohn's disease.

  2007cited by this paper
• High resolution colonoscopy in live mice

  2006cited by this paper
• Trichuris suis therapy for active ulcerative colitis: a randomized controlled trial.

  2005cited by this paper
• Meta-analysis of the relationship between CagA seropositivity and gastric cancer.

  2004cited by this paper
• Vomiting in the recently anticoagulated patient

  2004cited by this paper
• Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression.

  2003cited by this paper
• Meta-analysis of the relationship between cagA seropositivity and gastric cancer.

  2003cited by this paper
• Adenovirus early region 3(E3) immunomodulatory genes decrease the incidence of autoimmune diabetes in NOD mice.

  2001cited by this paper
• An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

  1999cited by this paper
• Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer*

  1998cited by this paper
• The MUC2 gene product: a human intestinal mucin.

  1998cited by this paper
• Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice.

  1993cited by this paper
• Helicobacter pylori infection and the risk of gastric carcinoma.

  1991cited by this paper
• Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration.

  1984cited by this paper

• Deciphering the TLR4 and NLRP3 Inflammasome Crosstalk for Therapeutic Restoration of Intestinal and Systemic Immunity.

  2026cites this paper
• Expression and significance analyses of microRNAs in colorectal cancer.

  2026cites this paper
• Modulation of Gut Microbiome and Metabolome as One of the Potential Mechanisms of Ketogenic Diet Effect in the Treatment of Epilepsy

  2025cites this paper
• Screening and eradication of Helicobacter pylori for gastric cancer prevention: Taipei Global Consensus II

  2025cites this paper
• Proteus mirabilis exacerbates ulcerative colitis by inhibiting mucin production

  2025cites this paper
• Panax notoginseng-Bletilla striata ameliorates reflux esophagitis by modulating NLRP3 inflammasomes and p38 MAPK pathway

  2025cites this paper
• Helicobacter pylori and Inflammatory Bowel Disease: Unraveling the Complex Interactions and Clinical Implications

  2025cites this paper
• Immunological relationship between Helicobacter pylori and anti-tumor necrosis factor α agents in inflammatory bowel disease

  2024cites this paper
• Effects of Helicobacter pylori infection on intestinal microbiota, immunity and colorectal cancer risk

  2024cites this paper
• Helicobacter pylori in Inflammatory Bowel Diseases: Active Protagonist or Innocent Bystander?

  2024cites this paper
• Debate on the relationship between Helicobacter pylori infection and inflammatory bowel disease: a bibliometric analysis

  2024cites this paper
• Britannilactone 1-O-acetate induced ubiquitination of NLRP3 inflammasome through TRIM31 as a protective mechanism against reflux esophagitis-induced esophageal injury

  2024cites this paper
• Bibliometric analysis of the correlation between H. pylori and inflammatory bowel disease

  2024cites this paper
• Impact of Helicobacter pylori Eradication on Inflammatory Bowel Disease Onset and Disease Activity: To Eradicate or Not to Eradicate?

  2024cites this paper
• Causality of Helicobacter pylori infection on eosinophilic esophagitis and potential pathogenesis: a Mendelian randomization study

  2024cites this paper
• Helicobacter pylori and gastric cancer: a critical approach to who really needs eradication

  2024cites this paper
• Immune Biology and Persistence of Helicobacter pylori in Gastric Diseases.

  2023cites this paper
• Bacterial Proteases in Helicobacter pylori Infections and Gastric Disease.

  2023cites this paper
• Regulation of gut microbiota and alleviation of DSS-induced colitis by vitexin

  2023cites this paper
• Immune response modulation in inflammatory bowel diseases by Helicobacter pylori infection

  2023cites this paper
• Gut microbiota mediated the therapeutic efficiency of Simiao decoction in the treatment of gout arthritis mice

  2023cites this paper
• Gastric microbiota dysbiosis and Helicobacter pylori infection

  2023cites this paper
• Inhibition of CD82 improves colitis by increasing NLRP3 deubiquitination by BRCC3

  2023cites this paper
• The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation in Helicobacter pylori-associated gastritis by regulating ROS and autophagy

  2023cites this paper
• The Efficacy of Cancer Immunotherapies Is Compromised by Helicobacter pylori Infection

  2022cites this paper
• Structural Characteristics of Inulin and Microcrystalline Cellulose and Their Effect on Ameliorating Colitis and Altering Colonic Microbiota in Dextran Sodium Sulfate-Induced Colitic Mice

  2022cites this paper
• Gastrointestinal microbiome and Helicobacter pylori: Eradicate, leave it as it is, or take a personalized benefit–risk approach?

  2022cites this paper
• Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems

  2022influential citation
• Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet

  2022cites this paper
• Mammalian Neuraminidases in Immune-Mediated Diseases: Mucins and Beyond

  2022cites this paper
• Insights into the underlying mechanisms and clinical management of microscopic colitis in relation to other gastrointestinal disorders

  2022cites this paper
• Irbesartan reprofiling for the amelioration of ethanol-induced gastric mucosal injury in rats: Role of inflammation, apoptosis, and autophagy.

  2022cites this paper
• Unravelling the pro-tumorigenic role of innate immune pattern recognition receptors in the gastric compartment

  2021cites this paper
• Assessment of a Small Molecule Synthetic Lignan in Enhancing Oxidative Balance and Decreasing Lipid Accumulation in Human Retinal Pigment Epithelia

  2021cites this paper
• Activation of AMPK/mTOR-driven autophagy and inhibition of NLRP3 inflammasome by saxagliptin ameliorate ethanol-induced gastric mucosal damage.

  2021cites this paper
• Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

  2021cites this paper
• The Relationship Between Helicobacter pylori and Inflammatory Bowel Disease.

  2021cites this paper
• The role of the microbiome and the NLRP3 inflammasome in the gut and lung

  2020cites this paper
• Viewpoint: Inflammatory bowel diseases among immigrants from low- to high-incidence countries: opportunities and considerations.

  2020cites this paper
• Mechanisms of persistence, innate immune activation and immunomodulation by the gastric pathogen Helicobacter pylori.

  2020cites this paper
• Lactobacillus plantarum AR113 alleviates DSS-induced colitis by regulating the TLR4/MyD88/NF-κB pathway and gut microbiota composition

  2020cites this paper
• Systematic review: gastrointestinal infection and incident inflammatory bowel disease

  2020cites this paper
• Review: Extragastric diseases and Helicobacter pylori

  2020cites this paper
• Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin 1

  2020cites this paper
• CMPK2 of triploid crucian carp is involved in immune defense against bacterial infection.

  2020cites this paper
• NLRP3 Inflammasome and Inflammatory Bowel Disease

  2019cites this paper
• Association Between Helicobacter pylori Exposure and Decreased Odds of Eosinophilic Esophagitis—a Systematic Review and Meta-analysis

  2019cites this paper
• BATF3-dependent dendritic cells drive both effector and regulatory T-cell responses in bacterially infected tissues

  2019cites this paper
• Inflammasomes in Colitis and Colorectal Cancer: Mechanism of Action and Therapies

  2019cites this paper
• Polymorphism in Toll-Like Receptors and Helicobacter Pylori Motility in Autoimmune Atrophic Gastritis and Gastric Cancer

  2019cites this paper
• Systematic review with meta‐analysis: association between Helicobacter pylori CagA seropositivity and odds of inflammatory bowel disease

  2019cites this paper
• Helicobacter pylori VacA Targets Myeloid Cells in the Gastric Lamina Propria To Promote Peripherally Induced Regulatory T-Cell Differentiation and Persistent Infection

  2019cites this paper
• The role of the changing human microbiome in the asthma pandemic.

  2019cites this paper
• Pretreatment with a Heat-Killed Probiotic Modulates the NLRP3 Inflammasome and Attenuates Colitis-Associated Colorectal Cancer in Mice

  2019cites this paper
• miRNA-29a inhibits colon cancer growth by regulation of the PTEN/Akt/GSK3β and Wnt/β-catenin signaling pathways.

  2018cites this paper
• Infections: a double-edge sword in autoimmunity.

  2018cites this paper
• Helicobacter pylori controls NLRP3 expression by regulating hsa-miR-223-3p and IL-10 in cultured and primary human immune cells

  2018cites this paper
• Molecular mimicry and autoimmunity.

  2018cites this paper
• Inflammasome activation and regulation during Helicobacter pylori pathogenesis.

  2018cites this paper
• Helicobacter pylori infection and inflammatory bowel disease: a crosstalk between upper and lower digestive tract

  2018cites this paper
• Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway

  2018cites this paper
• Helicobacter pylori Colonization Protects Against Chronic Experimental Colitis by Regulating Th17/Treg Balance.

  2018cites this paper
• Inflammasomes in the Gut Mucosal Homeostasis.

  2017cites this paper
• Regulation of Inflammatory Signaling in Health and Disease

  2017cites this paper
• Extragastric Gastrointestinal Manifestations of Helicobacter Pylori: Friend or Foe?

  2017cites this paper
• Inflammasomes and intestinal inflammation

  2017cites this paper
• Helicobacter pylori and Extragastric Diseases.

  2017cites this paper
• Cooperation of Gastric Mononuclear Phagocytes with Helicobacter pylori during Colonization

  2017cites this paper
• NLRP3 Controls the Development of Gastrointestinal CD11b+ Dendritic Cells in the Steady State and during Chronic Bacterial Infection.

  2017cites this paper
• Influence of Microbiota on Intestinal Immune System in Ulcerative Colitis and Its Intervention

  2017cites this paper
• [S2k-guideline Helicobacter pylori and gastroduodenal ulcer disease].

  2016cites this paper
• S2k-Guideline Helicobacter pylori and gastroduodenal ulcer disease

  2016cites this paper
• Helicobacter pylori: Does Gastritis Prevent Colitis?

  2016cites this paper
• Inflammasome Signaling and Bacterial Infections

  2016cites this paper
• Inflammasome Activation by Helicobacter pylori and Its Implications for Persistence and Immunity.

  2016cites this paper
• The Goldilocks Conundrum: NLR Inflammasome Modulation of Gastrointestinal Inflammation during Inflammatory Bowel Disease.

  2016cites this paper
• Metabolic Interaction of Helicobacter pylori Infection and Gut Microbiota

  2016cites this paper
• Systems-wide analyses of mucosal immune responses to Helicobacter pylori at the interface between pathogenicity and symbiosis

  2016influential citation
• The Gastrointestinal Tract Microbiota and Allergic Diseases

  2016cites this paper
• NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis

  2016cites this paper
• Proteus mirabilis: The Enemy Within.

  2015cites this paper
• Macrophages recognize the Helicobacter pylori type IV secretion system in the absence of toll‐like receptor signalling

  2015cites this paper
• Helicobacter pylori activates the TLR2/NLRP3/caspase-1/IL-18 axis to induce regulatory T-cells, establish persistent infection and promote tolerance to allergens

  2015cites this paper
• World Journal of Gastroenterology

  year unknowncites this paper