Prolongation of G1 and S phase in C-6 glioma cells treated with maple syrup urine disease metabolits. Morphologic and cell cycle studies.

No abstract is available for this paper.

• Publication year

  1978

• Venue

  Laboratory investigation; a journal of technical methods and pathology

• Publication date

  1978-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 564423
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The enzyme defect in maple syrup urine disease (branched chain ketoaciduria).

  2008cited by this paper
• INHIBITION OF ACETYLCHOLINE SYNTHESIS AND OF CARBOHYDRATE UTILIZATION BY MAPLE‐SYRUP‐URINE DISEASE METABOLITES

  1976cited by this paper
• Kinetic responses of murine sarcoma cells to radiation and hyperthermia in vivo and in vitro.

  1976cited by this paper
• Maple syrup urine disease: Branched-chain amino acid concentrations and metabolism in cultured human lymphoblasts

  1976cited by this paper
• CELL‐CYCLE ANALYSIS OF PERTURBED CELL POPULATIONS: COMPUTER SIMULATION OF SEQUENTIAL DNA DISTRIBUTIONS

  1976cited by this paper
• Relation of C-6 glial cells in culture to myelin.

  1975cited by this paper
• Quantitative increase of neuroglia-specific GFA protein in rat C-6 glioma cells in vitro

  1975cited by this paper
• Incorporation of 3H-uridine and 3H-uracil into RNA: a simple technique for the detection of mycoplasma contamination of cultured cells.

  1974cited by this paper
• Characteristics of the rat C-6 glioma maintained in organ culture systems. Production of glial fibrillary acidic protein in the absence of gliofibrillogenesis.

  1974cited by this paper
• Inhibition by the branched-chain 2-oxo acids of the 2-oxoglutarate dehydrogenase complex in developing rat and human brain.

  1974cited by this paper
• EFFECTS OF MAPLE SYRUP URINE DISEASE METABOLITES ON MOUSE l‐FIBROBLASTS IN VITRO: A FINE STRUCTURAL AND BIOCHEMICAL STUDY

  1974cited by this paper
• On the role of glial cells in the mammalian nervous system. Uptake, excretion, and metabolism of putative neurotransmitters by cultured glial tumor cells.

  1974cited by this paper
• Use of flow microfluorometry in detailed analysis of effects of chemical agents on cell cycle progression.

  1972cited by this paper
• The presence of 2′, 3′‐cyclic AMP 3′‐phosphohydrolase in glial cells in tissue culture

  1972cited by this paper
• Cyclic adenosine monophosphate-mediated stabilization of mouse neuroblastoma cell neuritis microtubules exposed to low temperature.

  1972cited by this paper
• The effects of gold thioglucose on mouse fibroblasts in vitro. Morphological and laser microprobe studies.

  1972cited by this paper
• Membrane dynamics in the action of dibutyryl adenosine 3':5'-cyclic monophosphate and testosterone on mammalian cells.

  1972cited by this paper
• Enzyme activity in classical and variant forms of maple syrup urine disease.

  1972cited by this paper
• Drug-induced differentiation of a rat glioma in vitro.

  1972cited by this paper
• Morphological transformation of Chinese hamster cells by dibutyryl adenosine cyclic 3':5'-monophosphate and testosterone.

  1971cited by this paper
• THICK FILAMENTS IN VASCULAR SMOOTH MUSCLE

  1971cited by this paper
• The inhibition of pyruvate decarboxylation in rat brain by -ketoisocaproic acid.

  1971cited by this paper
• The Automatic Analysis of Flm Curves

  1971cited by this paper
• Inhibition of alpha-oxoglutarate and pyruvate oxidation by alpha-oxoderivatives of leucine and valine in rat tissues.

  1970cited by this paper
• Synthesis by a clonal line of rat glial cells of a protein unique to the nervous system

  1970cited by this paper
• Mammalian alpha-keto acid dehydrogenase complexes. IV. Substrate specificities and kinetic properties of the pig heart pyruvate and 2-oxyoglutarate dehydrogenase complexes.

  1969cited by this paper
• Differentiated Rat Glial Cell Strain in Tissue Culture

  1968cited by this paper
• Maple syrup disease. Effects of dietary therapy on cerebral lipids.

  1967cited by this paper
• Further Observations on the Biochemical Lesion in Maple Syrup Urine Disease

  1967cited by this paper
• Cytoplasmic fibrils in living cultured cells

  1967cited by this paper
• BRAIN LIPIDS, PROTEOLIPIDS, AND FREE AMINO ACIDS IN MAPLE SYRUP URINE DISEASE *

  1966cited by this paper
• Influence of Alpha-Ketoacids on the Respiration of Brain in vitro. ∗

  1963cited by this paper
• CYTOCHEMISTRY AND ELECTRON MICROSCOPY

  1963cited by this paper
• Dietary Treatment of a Child with Maple Syrup Urine Disease (Branched-chain Ketoaciduria)

  1963cited by this paper
• Neuropathological observations in maple syrup urine disease: branched-chain ketoaciduria.

  1961cited by this paper
• Maple syrup urine disease.

  1961cited by this paper
• Maple syrup urine disease: branched-chain keto-aciduria.

  1960cited by this paper
• Maple syrup disease; isolation and identification of organic acids in the urine.

  1959cited by this paper
• A new syndrome: progressive familial infantile cerebral dysfunction associated with an unusual urinary substance.

  1954cited by this paper

• Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity

  2015cites this paper
• The effect of neurosphere culture conditions on the cellular metabolism of glioma cells.

  2015cites this paper
• Branched-Chain Amino Acids and Brain Metabolism

  2009cites this paper
• Leucine toxicity in a neuronal cell model with inhibited branched chain amino acid catabolism.

  2004cites this paper
• Study on established lymphoid cells in maple syrup urine disease. Correlation with clinical heterogeneity

  2004cites this paper
• Branched chain amino acids induce apoptosis in neural cells without mitochondrial membrane depolarization or cytochrome c release: implications for neurological impairment associated with maple syrup urine disease.

  2000cites this paper
• Primary Human Fibroblasts from a Maple Syrup Urine Disease Patient Undergo Apoptosis following Exposure to Physiological Concentrations of Branched Chain Amino Acids

  2000cites this paper
• Involvement of branched‐chain amino acid aminotransferase (Bcat1/Eca39) in apoptosis

  1999cites this paper
• Two Yeast Homologs of ECA39, a Target for c-Myc Regulation, Code for Cytosolic and Mitochondrial Branched-chain Amino Acid Aminotransferases*

  1996cites this paper
• Distribution pattern of acridine orange chromatin interaction products in rat glioma C6 cells at different phases of the cell cycle.

  1990cites this paper
• PROLIFERATION AND CELL CYCLE PARAMETERS OF ASTROCYTES

  1986cites this paper
• Differentiation and anaplasia in central neuroepithelial tumors.

  1984cites this paper
• The kinetics of human glioblastomas maintained in an organ culture system

  1983cites this paper
• Myelin proteins: degradation in rat brain initiated by metabolites causative of maple syrup urine disease.

  1983cites this paper
• Growth characteristics of the murine trisomy 19 thymus.

  1982cites this paper
• Growth Kinetics of Glioma Cells

  1982cites this paper
• Rat C‐6 Glioma Cells Maintained In an Organ Culture System: A Study of Kinetic Parameters

  1981cites this paper
• A collection device for small electronically sorted samples from flow cytometers.

  1980cites this paper