Long-acting insulin analog detemir displays reduced effects on adipocyte differentiation of human subcutaneous and visceral adipose stem cells.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  NMCD. Nutrition Metabolism and Cardiovascular Diseases

• Publication date

  2016-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.numecd.2015.11.010PMID 26947594
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Weight change upon once‐daily initiation of insulin detemir with or without dietary intervention in overweight or obese insulin‐naïve individuals with type 2 diabetes: results from the DIET trial

  2014cited by this paper
• Type 2 Diabetes Mellitus Management and Body Mass Index: Experiences with Initiating Insulin Detemir in the A1chieve Study

  2014cited by this paper
• Observational Study of Once-Daily Insulin Detemir in People with Type 2 Diabetes Aged 75 Years or Older

  2013cited by this paper
• Once‐daily initiation of basal insulin as add‐on to metformin: a 26‐week, randomized, treat‐to‐target trial comparing insulin detemir with insulin glargine in patients with type 2 diabetes

  2013cited by this paper
• Differences in Gene Expression and Cytokine Release Profiles Highlight the Heterogeneity of Distinct Subsets of Adipose Tissue-Derived Stem Cells in the Subcutaneous and Visceral Adipose Tissue in Humans

  2013cited by this paper
• Safety and effectiveness of insulin detemir in type 2 diabetes: results from the ASEAN cohort of the A₁chieve study.

  2013cited by this paper
• Effect of insulin analogues on 3t3‐l1 adipogenesis and lipolysis

  2011cited by this paper
• Insulin detemir versus insulin glargine for type 2 diabetes mellitus.

  2011cited by this paper
• Euglycemic Infusion of Insulin Detemir Compared With Human Insulin Appears to Increase Direct Current Brain Potential Response and Reduces Food Intake While Inducing Similar Systemic Effects

  2010cited by this paper
• Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling

  2010cited by this paper
• Role of UBC9 in the regulation of the adipogenic program in 3T3-L1 adipocytes.

  2010cited by this paper
• Differential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes

  2010cited by this paper
• Insulin detemir is a fully efficacious, low affinity agonist at the insulin receptor

  2010cited by this paper
• Insulin detemir causes increased symptom awareness during hypoglycaemia compared to human insulin

  2009cited by this paper
• Different Brain Responses to Hypoglycemia Induced by Equipotent Doses of the Long-Acting Insulin Analog Detemir and Human Regular Insulin in Humans

  2008cited by this paper
• Dynamics of fat cell turnover in humans

  2008cited by this paper
• Effect of insulin detemir, compared to human insulin, on 3T3-L1 adipogenesis.

  2008cited by this paper
• A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes

  2008cited by this paper
• Long-acting insulin analogues versus NPH human insulin in type 2 diabetes: a meta-analysis.

  2008cited by this paper
• Characteristics of signalling properties mediated by long-acting insulin analogue glargine and detemir in target cells of insulin.

  2008cited by this paper
• Proportional Dose-Response Relationship and Lower Within-Patient Variability of Insulin Detemir and NPH Insulin in Subjects With Type 1 Diabetes Mellitus

  2007cited by this paper
• Fat depot-related differences in gene expression, adiponectin secretion, and insulin action and signalling in human adipocytes differentiated in vitro from precursor stromal cells

  2007cited by this paper
• Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects

  2006cited by this paper
• Albumin inhibits adipogenesis and stimulates cytokine release from human adipocytes.

  2006cited by this paper
• Comparison of the effects on glucose and lipid metabolism of equipotent doses of insulin detemir and NPH insulin with a 16-h euglycaemic clamp

  2005cited by this paper
• Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes.

  2002cited by this paper
• Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use.

  2000cited by this paper
• Pharmacokinetic and pharmacodynamic properties of long-acting insulin analogue NN304 in comparison to NPH insulin in humans.

  2000cited by this paper
• Adipocyte differentiation and gene expression.

  2000cited by this paper
• Mechanism of protracted metabolic effects of fatty acid acylated insulin, NN304, in dogs: retention of NN304 by albumin

  1999cited by this paper
• Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigs

  1996influential reference

• Isolation of endothelial progenitor cells from human adipose tissue

  2025cites this paper
• A mixture of endocrine disrupting chemicals linked to lower birth weight induces adipogenesis and transcriptional changes related to birth weight alterations and diabetes

  2025cites this paper
• Involvement of a battery of investigated genes in lipid droplet pathophysiology and associated comorbidities

  2024cites this paper
• Insulin interacts with PPARγ agonists to promote bovine adipocyte differentiation.

  2024cites this paper
• Silencing ANGPTL8 reduces mouse preadipocyte differentiation and insulin signaling.

  2024cites this paper
• Second-Generation Antipsychotics Induce Metabolic Disruption in Adipose Tissue-Derived Mesenchymal Stem Cells Through an aPKC-Dependent Pathway

  2024cites this paper
• Transcription factors and miRNA act as contrary regulators of gene expression in the testis and epididymis of Bos indicus animals.

  2024cites this paper
• A Network Comprised of miR-15b and miR-29a Is Involved in Vascular Endothelial Growth Factor Pathway Regulation in Thymus Adipose Tissue from Elderly Ischemic Cardiomyopathy Subjects

  2023cites this paper
• Isolation and purification of brown algae fucoidan from Sargassum siliquosum and the analysis of anti-lipogenesis activity

  2021cites this paper
• Dysmetabolic adipose tissue in obesity: morphological and functional characteristics of adipose stem cells and mature adipocytes in healthy and unhealthy obese subjects

  2020cites this paper
• Optimizing adipogenic transdifferentiation of bovine mesenchymal stem cells: a prominent role of ascorbic acid in FABP4 induction

  2020cites this paper
• Insulin and Insulin Receptors in Adipose Tissue Development

  2019influential citation
• NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression

  2019cites this paper
• Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity

  2019cites this paper
• Adipocyte biology: It is time to upgrade to a new model

  2018cites this paper
• A comparative assessment of adipose‐derived stem cells from subcutaneous and visceral fat as a potential cell source for knee osteoarthritis treatment

  2017cites this paper