Molecular force balance measurements reveal that double-stranded DNA unbinds under force in rate-dependent pathways.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Biophysical Journal

• Publication date

  2008-06-15

• Fields of study

  Biology, Medicine, Physics, Chemistry

• Identifiers
  DOI 10.1529/biophysj.107.125427PMID 18339733PMCID PMC2397355
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Predicting the rupture probabilities of molecular bonds in series.

  2007cited by this paper
• Differential analysis of biomolecular rupture forces

  2006cited by this paper
• First-principles study of the adsorption of methanol at the α-Al2O3(0001) surface

  2006cited by this paper
• Dynamic force spectroscopy of the digoxigenin–antibody complex

  2006cited by this paper
• Antigen binding forces of single antilysozyme Fv fragments explored by atomic force microscopy.

  2005cited by this paper
• Molecular dynamics simulations of duplex stretching reveal the importance of entropy in determining the biomechanical properties of DNA.

  2005cited by this paper
• Modelling DNA stretching for physics and biology

  2004influential reference
• Simultaneous, coincident optical trapping and single-molecule fluorescence

  2004cited by this paper
• Bubble dynamics in double-stranded DNA.

  2003cited by this paper
• Geometry of the DNA strands within the RecA nucleofilament: role in homologous recombination

  2003cited by this paper
• DNA: A Programmable Force Sensor

  2003cited by this paper
• Dynamic single-molecule force spectroscopy: bond rupture analysis with variable spacer length

  2003cited by this paper
• Force-induced melting of the DNA double helix 1. Thermodynamic analysis.

  2001cited by this paper
• Intermolecular forces in biology

  2001cited by this paper
• Unbinding forces of single antibody-antigen complexes correlate with their thermal dissociation rates.

  2000cited by this paper
• Dynamic force spectroscopy of single DNA molecules.

  1999cited by this paper
• Energy landscapes of receptor–ligand bonds explored with dynamic force spectroscopy

  1999cited by this paper
• A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics.

  1998cited by this paper
• Microinterferometry: Three-Dimensional Reconstruction of Surface Microtopography for Thin-Film and Wetting Studies by Reflection Interference Contrast Microscopy (RICM).

  1998cited by this paper
• RNA polymerase as a molecular motor.

  1998cited by this paper
• Molecular Dynamics Simulation of DNA Stretching Is Consistent with the Tension Observed for Extension and Strand Separation and Predicts a Novel Ladder Structure

  1996influential reference
• Overstretching B-DNA: The Elastic Response of Individual Double-Stranded and Single-Stranded DNA Molecules

  1996cited by this paper
• Modelling extreme stretching of DNA.

  1996influential reference
• Adhesion forces between individual ligand-receptor pairs.

  1994cited by this paper
• Imaging optical thicknesses and separation distances of phospholipid vesicles at solid surfaces

  1993cited by this paper

• Modeling the Homologous Recombination Process: Methods, Successes and Challenges

  2023cites this paper
• Weak tension accelerates hybridization and dehybridization of short oligonucleotides

  2022cites this paper
• Calcul de configurations de tiges élastiques pour la modélisation des acides nucléiques

  2018cites this paper
• Remarkable similarity of force induced dsRNA conformational changes to stretched dsDNA and their detection using electrical measurements.

  2018cites this paper
• DNA partitions into triplets under tension in the presence of organic cations, with sequence evolutionary age predicting the stability of the triplet phase

  2017cites this paper
• Twisting short dsDNA with applied tension

  2017cites this paper
• Overstretching of B-DNA with various pulling protocols: Appearance of structural polymorphism and S-DNA.

  2017cites this paper
• Force measurements reveal how small binders perturb the dissociation mechanisms of DNA duplex sequences.

  2016cites this paper
• Evolutionary advantage of a broken symmetry in autocatalytic polymers explains fundamental properties of DNA

  2016cites this paper
• Parallel force assay for protein interactions

  2015cites this paper
• Parallel Force Assay for Protein-Protein Interactions

  2014cites this paper
• Significance of Molecular Dynamics Simulations for Life Sciences

  2014cites this paper
• Microfluidic & microrheological studies of protein interactions at the single–molecule & single–cell level

  2014cites this paper
• Force et couple dans les pinces magnétiques : paysage énergétique de la protéine hRad51 sur ADN double-brin

  2014cites this paper
• DNA SINGLE-MOLECULE FORCE SPECTROSCOPY STUDIES

  2013cites this paper
• Single-Molecule Mechanics of DNA

  2013cites this paper
• Lab on a Chip PAPER

  2013cites this paper
• Analysis of DNA-ligand interaction in a parallel force-based assay

  2013cites this paper
• Multiscale mechanobiology: mechanics at the molecular, cellular, and tissue levels

  2013cites this paper
• Konnektivität molekularer Domänen bei der kraftinduzierten Entfaltung einzelner Biomoleküle

  2012cites this paper
• Mesoscopic models for DNA stretching under force: New results and comparison with experiments

  2012cites this paper
• Direct measurement of the interaction force between immunostimulatory CpG–DNA and TLR9 fusion protein

  2012cites this paper
• Modulation der DNA-Mechanik durch Methylierung und Transkriptionsfaktoren

  2012cites this paper
• Quantifying how DNA stretches, melts and changes twist under tension

  2011cites this paper
• Single-Molecule Cut and Paste

  2011cites this paper
• On the structure and stretching of microhydrated DNA.

  2011cites this paper
• DNA Conformational Variations Induced by Stretching 3'5'-Termini Studied by Molecular Dynamics Simulations

  2011cites this paper
• On the role of London dispersion forces in biomolecular structure determination.

  2011cites this paper
• DNA structural changes under different stretching methods studied by molecular dynamics simulations.

  2010cites this paper
• DNA overstretched state: S-DNA form or force-induced melting? Comment on "Biophysical characterization of DNA binding from single molecule force measurements" by Mark C. Williams et al.

  2010cites this paper
• Stretched DNA investigated using molecular-dynamics and quantum-mechanical calculations.

  2010cites this paper
• Force Spectroscopy on Cells

  2010cites this paper
• Modeling the early stage of DNA sequence recognition within RecA nucleoprotein filaments

  2010cites this paper
• Study of force induced melting of dsDNA as a function of length and conformation

  2010cites this paper
• DNA stretching as a probe for nucleic acid interactions: Reply to Comments on "Biophysical characterization of DNA binding from single molecule force measurements" by Kathy R. Chaurasiya, Thayaparan Paramanathan, Micah J. McCauley, Mark C. Williams.

  2010cites this paper
• Optical tweezers experiments resolve distinct modes of DNA-protein binding.

  2009cites this paper
• Extracting Kinetic and Stationary Distribution Information from Short MD Trajectories via a Collection of Surrogate Diffusion Models.

  2009cites this paper
• Force-driven separation of short double-stranded DNA.

  2009cites this paper
• Structural basis of pathway-dependent force profiles in stretched DNA.

  2009cites this paper
• Quantifying DNA melting transitions using single-molecule force spectroscopy

  2009cites this paper
• Nanoscale manipulation and studies of individual biomolecules and DNA-based nanostructures

  2009cites this paper
• Deforming DNA: from physics to biology.

  2009cites this paper
• The structure of DNA overstretched from the 5′5′ ends differs from the structure of DNA overstretched from the 3′3′ ends

  2009cites this paper
• Overstretching of a 30 bp DNA duplex studied with steered molecular dynamics simulation: Effects of structural defects on structure and force-extension relation

  2009cites this paper
• Kraftspektroskopie an molekularen und supramolekularen biologischen Strukturen

  2008cites this paper
• Numerical Methods for Modeling Atomistic Trajectories with Diffusion SDEs

  2008cites this paper
• Supplementary Material Cytosine Methylation Alters Dna Mechanical Properties

  year unknowncites this paper