von Willebrand factor biosynthesis and partitioning between constitutive and regulated pathways of secretion after thrombin stimulation.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Blood

• Publication date

  1989-02-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1182/BLOOD.V73.3.706.706PMID 2783866
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An improved method for mRNA isolation and characterization of in vitro translation products by Western blotting.

  1987cited by this paper
• Perturbation of cultured human vascular endothelial cells by phorbol ester or thrombin alters the cellular von Willebrand factor distribution

  1987cited by this paper
• Topology and order of formation of interchain disulfide bonds in von Willebrand factor.

  1987cited by this paper
• Inducible secretion of large, biologically potent von Willebrand factor multimers.

  1986cited by this paper
• Molecular cloning of cDNA for human von Willebrand factor: authentication by a new method.

  1985cited by this paper
• Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization.

  1985cited by this paper
• Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA.

  1985cited by this paper
• Biosynthesis of von Willebrand protein by human endothelial cells: processing steps and their intracellular localization

  1984cited by this paper
• Platelet interaction with rabbit subendothelium in von Willebrand's disease: altered thrombus formation distinct from defective platelet adhesion.

  1984cited by this paper
• Nicotinic receptor stimulation activates enkephalin release and biosynthesis in adrenal chromaffin cells

  1984cited by this paper
• Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells.

  1984cited by this paper
• Alternative modes of enkephalin biosynthesis regulation by reserpine and cyclic AMP in cultured chromaffin cells.

  1984cited by this paper
• The effect of calcium on the secretion of factor VIII-related antigen by cultured human endothelial cells.

  1983cited by this paper
• Thrombin-mediated release of factor VIII antigen from human umbilical vein endothelial cells in culture.

  1982cited by this paper
• Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells

  1982cited by this paper
• Effects of thrombin on the integrity of monolayers of cultured human endothelial cells.

  1982cited by this paper
• Multimeric composition of factor VIII/von Willebrand factor following administration of DDAVP: implications for pathophysiology and therapy of von Willebrand's disease subtypes.

  1982cited by this paper
• Eukaryotic transcriptional regulation and chromatin-associated protein phosphorylation by cyclic AMP.

  1982cited by this paper
• Activation of phospholipases A2 and C in pig aortic endothelial cells synthesizing prostacyclin.

  1982cited by this paper
• Influence Of High Molecular Weight Factor VIII On The Expression Of Factor VIII Procoagulant Activity

  1981cited by this paper
• Variant von Willebrand's disease: characterization of two subtypes by analysis of multimeric composition of factor VIII/von Willebrand factor in plasma and platelets.

  1980cited by this paper
• Translational control of proinsulin synthesis by glucose

  1980cited by this paper
• Primary cultures of chromaffin cells: molecular mechanisms for the induction of tyrosine hydroxylase mediated by 8-Br-cyclic AMP.

  1979cited by this paper
• Human blood platelet adhesion to artery subendothelium is mediated by factor VIII–Von Willebrand factor bound to the subendothelium

  1979cited by this paper
• Stimulation of endothelial cell prostacyclin production by thrombin, trypsin, and the ionophore A 23187.

  1978cited by this paper
• Synthesis of factor VIII antigen by cultured guinea pig megakaryocytes.

  1977cited by this paper
• HUMAN VASCULAR ENDOTHELIAL CELLS IN CULTURE

  1974cited by this paper
• Ultrastructural studies on the platelet plug formation in bleeding time wounds from normal individuals and patients with von Willebrand's disease.

  1974cited by this paper
• Decreased adhesion of platelets to subendothelium in von Willebrand's disease.

  1974cited by this paper
• Synthesis of antihemophilic factor antigen by cultured human endothelial cells.

  1973cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Extracellular vesicles, hyperadhesive von willebrand factor, and outcomes of gastric cancer: a clinical observational study

  2023cites this paper
• ADAMTS13 protease or lack of von Willebrand factor protects irradiation and melanoma‐induced thrombotic microangiopathy in zebrafish

  2022cites this paper
• Diverse activities of von Willebrand factor in traumatic brain injury and associated coagulopathy

  2020cites this paper
• The Current Understanding of Molecular Pathogenesis of Quantitative von Willebrand Disease, Types 1 and 3

  2020cites this paper
• Pharmacokinetics, pharmacodynamics and safety of aptamers

  2018cites this paper
• Therapeutic targets in sickle cell disease

  2017cites this paper
• Dynamics of von Willebrand factor reactivity in sickle cell disease during vaso‐occlusive crisis and steady state

  2017cites this paper
• Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

  2017cites this paper
• Mutations in the D'D3 region of VWF traditionally associated with type 1 VWD lead to quantitative and qualitative deficiencies of VWF.

  2016cites this paper
• Lifecycle of Weibel-Palade bodies

  2016cites this paper
• Histones link inflammation and thrombosis through the induction of Weibel–Palade body exocytosis

  2016cites this paper
• Performance Related Factors Are the Main Determinants of the von Willebrand Factor Response to Exhaustive Physical Exercise

  2014cites this paper
• Genetic Ablation of Adamts13 Gene Dramatically Accelerates the Formation of Early Atherosclerosis in a Murine Model

  2012cites this paper
• Atherothrombosis in von Willebrand Disease: An Analysis of the Literature and Implications for Clinical Management

  2012cites this paper
• von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein

  2011cites this paper
• VEGF non-angiogenic functions in adult organ homeostasis: therapeutic implications

  2011cites this paper
• [State of the endothelium and hemostasis in acute leukemia].

  2011cites this paper
• Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease*

  2011cites this paper
• Von Willebrand Factor Structure and Function

  2011cites this paper
• Structure-function relationships of von Willebrand factor

  2009cites this paper
• Immunocytochemical localization of the urotensin-II receptor, UT, to rat and human tissues: relevance to function.

  2008cites this paper
• Induction of intracellular signalling in human endothelial cells by the hyaluronan-binding protease involves two distinct pathways

  2006cites this paper
• Functional and immunocytochemical evidence for a role of ghrelin and des-octanoyl ghrelin in the regulation of vascular tone in man.

  2006cites this paper
• Predictors of the rise in vWF after ST elevation myocardial infarction: implications for treatment strategies and clinical outcome: An ENTIRE-TIMI 23 substudy.

  2005cites this paper
• Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells.

  2005cites this paper
• How to Roll an Endothelial Cigar: The Biogenesis of Weibel‐Palade Bodies

  2004cites this paper
• Critical role of the vascular endothelial cell in health and disease: a review article

  2004cites this paper
• The role of cellular stress during cold ischaemic and reperfusion injury

  2002cites this paper
• Weibel‐Palade Body Membrane Proteins Exhibit Differential Trafficking After Exocytosis in Endothelial Cells

  2000cites this paper
• In vivo regulation of von willebrand factor synthesis: von Willebrand factor production in endothelial cells after lung transplantation between normal pigs and von Willebrand factor-deficient pigs.

  1999cites this paper
• Secretory pathways in endothelin synthesis

  1999cites this paper
• von Willebrand factor does not influence atherogenesis in arteries subjected to altered shear stress.

  1998cites this paper
• Shear Stress von Willebrand Factor Does Not Influence Atherogenesis in Arteries Subjected to Altered

  1998cites this paper
• Evidence using immunoelectron microscopy for regulated and constitutive pathways in the transport and release of endothelin.

  1998cites this paper
• Evidence of a local mechanism for desmopressin-induced tissue-type plasminogen activator release in human forearm.

  1998cites this paper
• Induction of fibrinogen biosynthesis and secretion from cultured pulmonary epithelial cells.

  1997cites this paper
• Thrombin modulates vectorial secretion of extracellular matrix proteins in cultured endothelial cells.

  1997cites this paper
• Regulated exocytosis in vascular endothelial cells can be triggered by intracellular guanine nucleotides and requires a hydrophobic, thiol-sensitive component. Studies of regulated von Willebrand factor secretion from digitonin permeabilized endothelial cells.

  1997cites this paper
• Sympathoadrenal Activation and Muscarinic Receptor Stimulation Induce Acute Release of Tissue-Type Plasminogen Activator but not von Willebrand Factor across the Human Forearm

  1997cites this paper
• Aberrant vascularity and von Willebrand factor distribution in inflamed synovial membrane.

  1996cites this paper
• Hypothyroidism and von Willebrand factor.

  1995cites this paper
• Studies on the acute release of tissue-type plasminogen activator from human endothelial cells in vitro and in rats in vivo: evidence for a dynamic storage pool.

  1995cites this paper
• Morphological alterations in endothelial cells associated with the release of von Willebrand factor after thrombin generation in vivo.

  1994cites this paper
• Heparin Enhances Endothelial Cell von Willebrand Factor Content by Growth Factor Dependent Mechanisms

  1994cites this paper
• Vascular wall von Willebrand factor in human diabetic retinopathy.

  1994cites this paper
• The control of production and release of haemostatic factors in the endothelial cell.

  1993cites this paper
• Von Willebrand Factor and P-Selectin Targeting to and Release from Endothelial Cell-Specific Storage Granules

  1993cites this paper
• von Willebrand Factor Biosynthesis and Processing a

  1991cites this paper
• Tumor-secreted vascular permeability factor increases cytosolic Ca2+ and von Willebrand factor release in human endothelial cells.

  1991cites this paper
• Regulated secretion in vascular endothelium.

  1991cites this paper
• Cell biology of von Willebrand factor.

  1990cites this paper
• von Willebrand disease.

  1990cites this paper