Small family, big impact: RNL helper NLRs and their importance in plant innate immunity

Plants evolved a sophisticated, receptor-based, innate immune system. Cell surface localized pattern recognition (PRR) and intracellular nucleotide-binding leucine-rich repeat (NLR) receptors detect pathogen-associated molecular patterns or pathogen-derived effector molecules, respectively, and induce a range of common immune responses. These include Ca 2+ fluxes, reactive oxygen species production, and mitogen-activated protein kinase activation [1]. Recent studies have demonstrated an interdependency and mutual potentiation of the 2 receptor systems [2,3]. Based on their N-terminal domains and their phylogeny, NLRs are clas-sified in coiled-coil (CC) domain, Toll-like/interleukin-1 receptor resistance (TIR) domain, and RESISTANCE

• Publication year

  2023

• Venue

  PLoS Pathogens

• Publication date

  2023-04-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1371/journal.ppat.1011315PMID 37079491PMCID 10118176
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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