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Biobanks: The unmet need in heart failure management.

G. Manzi,M. Mariani,D. Filomena,R. Poscia,P. Severino,A. Iaconelli,Tommaso Recchioni,R. Madonna,C. Vizza,R. Badagliacca

Published 2023 in Vascular pharmacology

ABSTRACT

Heart failure (HF) represents a major health and economic issue, with increasing morbidity and mortality in spite of novel therapeutic weapons. The disappointing results of HF management may be due to the current therapeutic approach based on the paradigm "one fits all", that cannot apply to a complex and multifaceted syndrome as HF. At this regard, the European Union is developing policies to move from reductionism to precision medicine, in order to identify specific disease biomarkers and develop targeted therapeutic strategies. The institution of biobanks may represent the game changer in HF scenario, providing a collection of human biological materials with the related medical and epidemiological data fueling the development of personalized therapeutic approach and fostering current and/or future research projects.

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