Synthetic microbial community (SynCom) biosensors are a promising technology for detecting and responding to environmental cues and target molecules. SynCom biosensors use engineered microorganisms to create a more complex and diverse sensing system, enabling them to respond to stimuli with enhanced sensitivity and accuracy. Here, we give a definition of SynCom biosensors, outline their construction workflow, and discuss current biosensing technology. We also highlight the challenges and future for developing and optimizing SynCom biosensors and the potential applications in agriculture and food management, biotherapeutic development, home sensing, urban and environmental monitoring, and the One Health foundation. We believe SynCom biosensors could be used in a real-time and remote-controlled manner to sense the chaos of constantly dynamic environments.
Perspective on the development of synthetic microbial community (SynCom) biosensors.
Jing Yuan,Kankan Zhao,Xiangfeng Tan,Ran Xue,Yuan Zeng,C. Ratti,P. Trivedi
Published 2023 in Trends in Biotechnology
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- Publication year
2023
- Venue
Trends in Biotechnology
- Publication date
2023-05-01
- Fields of study
Agricultural and Food Sciences, Biology, Engineering, Environmental Science, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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