The model that glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) take a direct transport route to the apical membrane of epithelial cells has recently been challenged. In this issue, Paladino et al. (p. 1023) and Hua et al. (p. 1035) show that the original view nevertheless holds. This closes a chapter in the winding story of GPI-AP trafficking but opens another phase, as the controversy has stimulated the development of new methodology.
Controversy fuels trafficking of GPI-anchored proteins
Published 2006 in Journal of Cell Biology
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- Publication year
2006
- Venue
Journal of Cell Biology
- Publication date
2006-03-27
- Fields of study
Biology, Medicine
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- External record
- Source metadata
Semantic Scholar, PubMed
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