MRI free water as a biomarker for cognitive performance: Validation in the markvcid consortium

P. Maillard,Laura J. Hillmer,Hanzhang Lu,K. Arfanakis,B. Gold,Christopher E. Bauer,J. Kramer,A. Staffaroni,L. Stables,Danny J. J. Wang,S. Seshadri,C. Satizabal,A. Beiser,Mohamad Habes,M. Fornage,T. Mosley,G. Rosenberg,Baljeet Singh,Herpreet Singh,K. Schwab,R. Corriveau,K. Helmer,S. Greenberg,C. Decarli,Caprihan Arvind

Published 2023 in Alzheimer's & Dementia

ABSTRACT

Free Water (FW), a Diffusion Tensor Imaging‐based biomarker kit has been demonstrated by the MarkVCID consortium to have excellent instrumental validity1. We sought to determine its clinical relevance by investigating association of FW with clinically meaningful aspects of vascular contributions to cognitive impairment and dementia (VCID) in the MarkVCID consortium cohort as well as 5 independent settings.

PUBLICATION RECORD

Publication year
2023
Venue
Alzheimer's & Dementia
Publication date
2023-06-01
Fields of study
Not labeled
Identifiers
DOI 10.1002/alz.064304
External record
Open on Semantic Scholar
Source metadata
Semantic Scholar

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