CLPTM1L is a GPI-anchoring pathway component targeted by HCMV

Inbal Kol,Ahmed Rishiq,Mevaseret Cohen,S. Kahlon,Ophir Pick,Liat Dassa,Natan Stein,Y. Bar-On,D. Wolf,Einat Seidel,O. Mandelboim

Published 2023 in Journal of Cell Biology

ABSTRACT

Kol et al. identify CLPTM1L as a novel component of the GPI-anchoring pathway and show that it is targeted by HCMV. This discovery sheds light on basic aspects of cell biology, as well as on the sophistication with which viruses manipulate the immune response.

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