The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  American Journal of Human Genetics

• Publication date

  2002-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1086/340256PMID 11938494PMCID PMC447596
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The life cycle

  2002cited by this paper
• Eci1p uses a PTS1 to enter peroxisomes: either its own or that of a partner, Dci1p.

  2001cited by this paper
• Expression of MUL, a gene encoding a novel RBCC family ring-finger protein, in human and mouse embryogenesis.

  2001cited by this paper
• The life cycle of the peroxisome

  2001cited by this paper
• The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators.

  2001cited by this paper
• Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

  2001cited by this paper
• A Diverse Family of Proteins Containing Tumor Necrosis Factor Receptor-associated Factor Domains*

  2001influential reference
• The tripartite motif family identifies cell compartments

  2001cited by this paper
• Molecular Anatomy of the Peroxin Pex12p

  2000cited by this paper
• The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor.

  2000cited by this paper
• Regulation of Microtubule Dynamics and Myogenic Differentiation by Murf, a Striated Muscle Ring-Finger Protein

  2000cited by this paper
• The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases.

  2000cited by this paper
• The genetics of peroxisome biogenesis.

  2000influential reference
• RING for destruction?

  2000cited by this paper
• RING finger proteins: mediators of ubiquitin ligase activity.

  2000cited by this paper
• Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions.

  2000cited by this paper
• Gene encoding a new RING-B-box-Coiled-coil protein is mutated in mulibrey nanism

  2000influential reference
• RING domains: master builders of molecular scaffolds?

  2000cited by this paper
• The domains of death: evolution of the apoptosis machinery.

  1999cited by this paper
• The RING finger/B-box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans.

  1999cited by this paper
• Mulibrey nanism and Wilms tumor.

  1999cited by this paper
• Cloning and Characterization of a Novel RING Finger Protein That Interacts with Class V Myosins*

  1999cited by this paper
• Molecular genetics of peroxisomal disorders.

  1998influential reference
• Mutations in PEX10 is the cause of Zellweger peroxisome deficiency syndrome of complementation group B.

  1998cited by this paper
• Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

  1998cited by this paper
• Enlarged Peroxisomes Are Present in Oleic Acid–grown Yarrowia lipolytica Overexpressing the PEX16 Gene Encoding an Intraperoxisomal Peripheral Membrane Peroxin

  1997cited by this paper
• Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

  1997cited by this paper
• Subcellular fractionation : a practical approach

  1997cited by this paper
• The RING finger domain: a recent example of a sequence-structure family.

  1996cited by this paper
• L-lactate dehydrogenase A4- and A3B isoforms are bona fide peroxisomal enzymes in rat liver. Evidence for involvement in intraperoxisomal NADH reoxidation.

  1996cited by this paper
• Does this have a familiar RING?

  1996cited by this paper
• L-Lactate Dehydrogenase A- and AB Isoforms Are Bona Fide Peroxisomal Enzymes in Rat Liver

  1996cited by this paper
• Mulibrey nanism: three additional patients and a review of 39 patients.

  1995cited by this paper
• The N‐terminal part of TIF1, a putative mediator of the ligand‐dependent activation function (AF‐2) of nuclear receptors, is fused to B‐raf in the oncogenic protein T18.

  1995cited by this paper
• Identification of three distinct peroxisomal protein import defects in patients with peroxisome biogenesis disorders.

  1995cited by this paper
• Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders

  1995cited by this paper
• Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p

  1995cited by this paper
• Peroxisomal functions in Mulibrey nanism

  1994cited by this paper
• A human gene responsible for Zellweger syndrome that affects peroxisome assembly.

  1992cited by this paper
• The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

  1991cited by this paper
• Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene

  1988cited by this paper
• A case of Mulibrey nanism with associated Wilms' tumor

  1980cited by this paper
• Mulibrey nanism, an autosomal recessive syndrome with pericardial constriction.

  1973cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970influential reference
• Article Functional Characterization of the Opitz Syndrome Gene Product (midin): Evidence for Homodimerization and Association with Microtubules throughout the Cell Cycle

  year unknowncited by this paper

• TRIM37-mediated stabilization of PEX5 via monoubiquitination attenuates oxidative stress and demyelination in multiple sclerosis insights from EAE and LPC-induced experimental models

  2025cites this paper
• From Human to Mouse and Back: Genetic and Genomic Ta(i)les of Islet Dysfunction in Type 2 Diabetes.

  2025cites this paper
• TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization

  2025cites this paper
• Mesoscale regulation of microtubule-organizing centers by the E3 ligase TRIM37

  2025cites this paper
• A proteomic study of the downregulation of TRIM37 on chondrocytes: Implications for the MULIBREY syndrome.

  2024cites this paper
• Mesoscale regulation of MTOCs by the E3 ligase TRIM37

  2024cites this paper
• Skeletal Phenotype in Mulibrey Nanism, A Monogenic Skeletal Dysplasia With Fibrous Dysplasia

  2024cites this paper
• TRIM37 interacts with EZH2 to epigenetically suppress PTCH1 and regulate stemness in glioma stem cells through sonic hedgehog pathway

  2024cites this paper
• TRIM37 employs peptide motif recognition and substrate-dependent oligomerization to prevent ectopic spindle pole assembly

  2024cites this paper
• The TRIM37 variants in Mulibrey nanism patients paralyze follicular helper T cell differentiation

  2023cites this paper
• Liver pathology and biochemistry in patients with mutations in TRIM37 gene (Mulibrey nanism)

  2022cites this paper
• TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin

  2021cites this paper
• TRIM37 overexpression is associated with chemoresistance in hepatocellular carcinoma via activating the AKT signaling pathway

  2021cites this paper
• Autophagy Regulation by Crosstalk between miRNAs and Ubiquitination System

  2021cites this paper
• TRIM37: a critical orchestrator of centrosome function

  2021cites this paper
• Neurodevelopmental Disorders (NDD) Caused by Genomic Alterations of the Ubiquitin-Proteasome System (UPS): the Possible Contribution of Immune Dysregulation to Disease Pathogenesis

  2021cites this paper
• Wilms tumor with Mulibrey Nanism: A case report and review of literature

  2021cites this paper
• TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity

  2021cites this paper
• Circular RNA circRNA_101996 promoted cervical cancer development by regulating miR‐1236‐3p/TRIM37 axis

  2021cites this paper
• Transcriptomic profiling of peroxisome-related genes reveals a novel prognostic signature in hepatocellular carcinoma

  2020cites this paper
• TRIM37 is highly expressed during mitosis in CHON-002 chondrocytes cell line and is regulated by miR-223.

  2020cites this paper
• Proteostasis and Disease: From Basic Mechanisms to Clinics

  2020cites this paper
• TRIM E3 Ubiquitin Ligases in Rare Genetic Disorders.

  2020cites this paper
• TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin stability

  2020cites this paper
• Peroxisomal Disorders

  2019cites this paper
• Silencing TRIM37 inhibits the proliferation and migration of non-small cell lung cancer cells

  2018cites this paper
• An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.

  2018cites this paper
• Premature ovarian insufficiency and early depletion of the ovarian reserve in the monogenic Mulibrey nanism disorder

  2018cites this paper
• TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import

  2017influential citation
• Renal findings in patients with Mulibrey nanism

  2017cites this paper
• Knockdown of Tripartite Motif-Containing Protein 37 (TRIM37) Inhibits the Proliferation and Tumorigenesis in Colorectal Cancer Cells.

  2017cites this paper
• TRIM37 promotes tumor cell proliferation and drug resistance in pediatric osteosarcoma

  2017cites this paper
• E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to Degeneration

  2017cites this paper
• TRIM37 promotes epithelial-mesenchymal transition in colorectal cancer

  2017cites this paper
• [Hereditary peroxisomal diseases].

  2016cites this paper
• Trim37-deficient mice recapitulate several features of the multi-organ disorder Mulibrey nanism

  2016cites this paper
• The peroxisomal receptor dislocation pathway: to the exportomer and beyond.

  2014cites this paper
• Cloning and expression analysis of a MATH-domain gene BnaMT-1 in Brassica napus : Cloning and expression analysis of a MATH-domain gene BnaMT-1 in Brassica napus

  2013cites this paper
• Refractory congestive heart failure following delayed pericardectomy in a 12-year-old child with Mulibrey nanism due to a novel mutation in TRIM37

  2013cites this paper
• The exportomer: the peroxisomal receptor export machinery

  2013cites this paper
• TRIM/RBCC Proteins

  2013cites this paper
• Discovering regulators of centriole biogenesis through siRNA-based functional genomics in human cells.

  2013cites this paper
• Genetic Predisposition and Genetic Susceptibility

  2012cites this paper
• The tripartite motif: structure and function.

  2012cites this paper
• Mulibrey nanism: Characterization of hypogonadism, infertility and tumors

  2012cites this paper
• Characterization of Hypogonadism , Infertility and Tumors

  2012cites this paper
• PML nuclear bodies and other TRIM-defined subcellular compartments.

  2012cites this paper
• Testicular failure and male infertility in the monogenic Mulibrey nanism disorder.

  2011cites this paper
• TRIM37 (tripartite motif-containing 37)

  2011cites this paper
• Review and hypothesis: Syndromes with severe intrauterine growth restriction and very short stature—Are they related to the epigenetic mechanism(s) of fetal survival involved in the developmental origins of adult health and disease?

  2010cites this paper
• High frequency of tumours in Mulibrey nanism

  2009cites this paper
• Gynecological tumors in Mulibrey nanism and role for RING finger protein TRIM37 in the pathogenesis of ovarian fibrothecomas

  2009cites this paper
• Novel insights into the localization and functions of tripartite motif-containing 22.

  2008cites this paper
• Growth and Growth Hormone Therapy in Subjects With Mulibrey Nanism

  2007cites this paper
• Phylogeny of the TRAF/MATH domain.

  2007cites this paper
• Tissue expression of the mulibrey nanism-associated Trim37 protein in embryonic and adult mouse tissues

  2006cites this paper
• Subclassification of the RBCC/TRIM Superfamily Reveals a Novel Motif Necessary for Microtubule Binding*

  2006cites this paper
• Characterization of the TRIM37 gene and mutations underlying mulibrey nanism

  2006influential citation
• Biochemical and Cell Biological Studies of TRIM37 Defective in Mulibrey Nanism

  2006cites this paper
• Characterisation of the mulibrey nanism-associated TRIM37 gene: transcription initiation, promoter region and alternative splicing.

  2006cites this paper
• Wilms’ tumor and novel TRIM37 mutations in an Australian patient with mulibrey nanism

  2006cites this paper
• TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase.

  2005cites this paper
• TRIM/RBCC, a novel class of ‘single protein RING finger’ E3 ubiquitin ligases

  2005cites this paper
• Insulin resistance syndrome in subjects with mutated RING finger protein TRIM37.

  2005influential citation
• Novel mutations in the TRIM37 gene in Mulibrey Nanism

  2004influential citation
• Failure of sexual maturation in Mulibrey nanism.

  2004cites this paper
• Metabolic and molecular basis of peroxisomal disorders: A review

  2004cites this paper
• CORRECTION

  2004cites this paper
• A novel splice site mutation in the TRIM37 gene causes mulibrey nanism in a Turkish family with phenotypic heterogeneity

  2003cites this paper
• The Finnish disease heritage III: the individual diseases

  2003cites this paper
• Mulibrey Heart Disease: Clinical Manifestations, Long-Term Course, and Results of Pericardiectomy in a Series of 49 Patients Born Before 1985

  2003cites this paper
• Detailed gene copy number and RNA expression analysis of the 17q12–23 region in primary breast cancers

  2003cites this paper
• DFNA49, a novel locus for autosomal dominant non-syndromic hearing loss, maps proximal to DFNA7/DFNM1 region on chromosome 1q21-q23

  2003cites this paper
• Mulibrey nanism--a novel peroxisomal disorder.

  2003cites this paper
• Atlas of Genetics and Cytogenetics in Oncology and Haematology

  2002cites this paper
• Trim 37-deficient mice recapitulate several features of the multi-organ disorder

  year unknowncites this paper