Combination of caspase transfer using the human telomerase reverse transcriptase promoter and conventional therapies for malignant glioma cells.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  International Journal of Oncology

• Publication date

  2004-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/IJO.25.1.57PMID 15201989
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inhibition of telomerase activity in malignant glioma cells correlates with their sensitivity to temozolomide

  2003cited by this paper
• Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells.

  2003cited by this paper
• Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor.

  2003cited by this paper
• Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of the expression of cyclin-dependent kinase inhibitors, and autophagy.

  2003cited by this paper
• Down-regulation of telomerase activity in malignant glioma cells by p27KIP1.

  2003cited by this paper
• Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain

  2002cited by this paper
• Caspase-independent cell deaths.

  2002cited by this paper
• Radiotherapy for newly diagnosed malignant glioma in adults: a systematic review.

  2002cited by this paper
• Caspase-8 Gene Therapy Using the Human Telomerase Reverse Transcriptase Promoter for Malignant Glioma Cells

  2002cited by this paper
• Biodegradable polymer implants to treat brain tumors.

  2001cited by this paper
• p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells.

  2001cited by this paper
• Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter.

  2001cited by this paper
• A Novel Telomerase-Specific Gene Therapy: Gene Transfer of Caspase-8 Utilizing the Human Telomerase Catalytic Subunit Gene Promoter

  2000cited by this paper
• Adenovirus-Mediated Transfer of Caspase-8 Augments Cell Death in Gliomas: Implication for Gene Therapy

  2000cited by this paper
• Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells.

  1999cited by this paper
• The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter.

  1999cited by this paper
• Cell-killing by paclitaxel in a metastatic murine melanoma cell line is mediated by extensive telomere erosion with no decrease in telomerase activity.

  1999cited by this paper
• Attenuation of WAF1/Cip1 expression by an antisense adenovirus expression vector sensitizes glioblastoma cells to apoptosis induced by chemotherapeutic agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin.

  1999cited by this paper
• Telomerase activity as a measure for monitoring radiocurability of tumor cells

  1999cited by this paper
• Generation of Constitutively Active Recombinant Caspases-3 and -6 by Rearrangement of Their Subunits*

  1998cited by this paper
• Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation

  1998cited by this paper
• Retroviral transfer of CPP32beta gene into malignant gliomas in vitro and in vivo.

  1998cited by this paper
• Proliferation, migration and invasion of human glioma cells exposed to paclitaxel (Taxol) in vitro.

  1997cited by this paper
• Involvement of p53 and WAF1/CIP1 in gamma-irradiation-induced apoptosis of retinoblastoma cells.

  1997cited by this paper
• Decline in telomerase activity as a measure of tumor cell killing by antineoplastic agents in vitro.

  1997cited by this paper
• A survey of telomerase activity in human cancer.

  1997cited by this paper
• Adenovirus‐mediated p53 gene transfer suppresses growth of human glioblastoma cells in vitro and in vivo

  1996cited by this paper
• Human ICE/CED-3 protease nomenclature.

  1996cited by this paper
• Phase II study of paclitaxel in patients with recurrent malignant glioma.

  1996cited by this paper
• FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

  1996cited by this paper
• Apoptosis in the pathogenesis and treatment of disease

  1995cited by this paper
• Interleukin-1 beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells.

  1995cited by this paper
• Activation of telomerase in a human tumor.

  1994cited by this paper
• Temozolomide: a new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumours.

  1993cited by this paper
• Brain Tumor Working Group Report on the 9th International Conference on Brain Tumor Research and Therapy

  1993cited by this paper
• Intra-arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous system.

  1984cited by this paper
• A phase I study of intracarotid artery infusion of cis-Diamminedichloroplatinum(II) in patients with recurrent malignant intracerebral tumors.

  1982cited by this paper

• Brain-targeted, drug-loaded solid lipid nanoparticles against glioblastoma cells in culture.

  2021cites this paper
• nm23‐H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice

  2013cites this paper
• Eukaryotic expression vectors bearing genes encoding cytotoxic proteins for cancer gene therapy.

  2012cites this paper
• Proteases as therapeutics.

  2011cites this paper
• Mechanism of thalidomide to enhance cytotoxicity of temozolomide in U251-MG glioma cells in vitro.

  2009cites this paper
• The sensitization of glioma cells to cisplatin and tamoxifen by the use of catechin

  2009cites this paper
• Enhanced suicide gene therapy using a tumor-specific promoter in combination with cisplatin.

  2009cites this paper
• Molecular strategies for the treatment of malignant glioma—genes, viruses, and vaccines

  2008cites this paper
• Telomerase-specific oncolytic virotherapy for human hepatocellular carcinoma.

  2008cites this paper
• Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers

  2008cites this paper
• Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway

  2008cites this paper
• Targeting Telomerase: Therapeutic Options for Cancer Treatment

  2008cites this paper
• New anti-proliferative agent, MK615, from Japanese apricot "Prunus mume" induces striking autophagy in colon cancer cells in vitro.

  2007cites this paper
• Telomerase activity and hTERT mRNA expression in glial tumors.

  2006cites this paper
• Survival prediction in patients with glioblastoma multiforme by human telomerase genetic variation.

  2006cites this paper
• Methods of Determining Apoptosis in Neuro-Oncology

  2006cites this paper
• Radiogenic Therapy: Novel Approaches for Enhancing Tumor Radiosensitivity

  2005cites this paper
• Telomerase-dependent gene therapy.

  2005cites this paper
• Caspases: potential targets for regulating cell death

  2004cites this paper